Value of genomics in breeding objectives for beef cattle

Detalhes bibliográficos
Autor(a) principal: MacNeil,Michael D.
Data de Publicação: 2016
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016001200794
Resumo: ABSTRACT The objective of this research was to discern the contribution of genomic information to multiple-trait breeding objectives and thus understand the economic value of that information. True genetic values were simulated for each of n, possibly correlated, traits. These true genetic values, combined with uncorrelated random noise, resulted in both genomic and phenotypic estimated breeding values, EBVg and EBVp, respectively. The separate EBV were then merged (blended) as a function of their respective accuracies to produce a unified EBV for each of the n traits. Finally, for each simulated animal (N = 10000), the sum of products of economic weights and EBV was calculated to predict the economic value (net merit) of the individual. Accuracies of the EBV for the individual traits and net merit were calculated as correlations between predicted and true values. Predicted responses to selection for individual traits included in the breeding objectives were enhanced from 9% to 76% with the greatest benefit accorded to those economically relevant traits that are recorded after selection decisions are made at one year of age, measured less frequently in national cattle evaluation, or often predicted using information from indicator traits. Combining the EBV to predict net merit for terminal and maternal breeding objectives resulted in predicted increases in selection response due to incorporation of genomic information of 27% and 57%, respectively. The results are interpreted to suggest that the economic benefit to be derived from selection based on a multiple-trait economic breeding objective, which is predicted using genomically enhanced EBV, can substantially exceed the present day cost of genotyping the candidates for selection.
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spelling Value of genomics in breeding objectives for beef cattleanimal breedingassisted selectiongenetic gainproduction systemABSTRACT The objective of this research was to discern the contribution of genomic information to multiple-trait breeding objectives and thus understand the economic value of that information. True genetic values were simulated for each of n, possibly correlated, traits. These true genetic values, combined with uncorrelated random noise, resulted in both genomic and phenotypic estimated breeding values, EBVg and EBVp, respectively. The separate EBV were then merged (blended) as a function of their respective accuracies to produce a unified EBV for each of the n traits. Finally, for each simulated animal (N = 10000), the sum of products of economic weights and EBV was calculated to predict the economic value (net merit) of the individual. Accuracies of the EBV for the individual traits and net merit were calculated as correlations between predicted and true values. Predicted responses to selection for individual traits included in the breeding objectives were enhanced from 9% to 76% with the greatest benefit accorded to those economically relevant traits that are recorded after selection decisions are made at one year of age, measured less frequently in national cattle evaluation, or often predicted using information from indicator traits. Combining the EBV to predict net merit for terminal and maternal breeding objectives resulted in predicted increases in selection response due to incorporation of genomic information of 27% and 57%, respectively. The results are interpreted to suggest that the economic benefit to be derived from selection based on a multiple-trait economic breeding objective, which is predicted using genomically enhanced EBV, can substantially exceed the present day cost of genotyping the candidates for selection.Sociedade Brasileira de Zootecnia2016-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016001200794Revista Brasileira de Zootecnia v.45 n.12 2016reponame:Revista Brasileira de Zootecnia (Online)instname:Sociedade Brasileira de Zootecnia (SBZ)instacron:SBZ10.1590/s1806-92902016001200010info:eu-repo/semantics/openAccessMacNeil,Michael D.eng2017-01-13T00:00:00Zoai:scielo:S1516-35982016001200794Revistahttps://www.rbz.org.br/pt-br/https://old.scielo.br/oai/scielo-oai.php||bz@sbz.org.br|| secretariarbz@sbz.org.br1806-92901516-3598opendoar:2017-01-13T00:00Revista Brasileira de Zootecnia (Online) - Sociedade Brasileira de Zootecnia (SBZ)false
dc.title.none.fl_str_mv Value of genomics in breeding objectives for beef cattle
title Value of genomics in breeding objectives for beef cattle
spellingShingle Value of genomics in breeding objectives for beef cattle
MacNeil,Michael D.
animal breeding
assisted selection
genetic gain
production system
title_short Value of genomics in breeding objectives for beef cattle
title_full Value of genomics in breeding objectives for beef cattle
title_fullStr Value of genomics in breeding objectives for beef cattle
title_full_unstemmed Value of genomics in breeding objectives for beef cattle
title_sort Value of genomics in breeding objectives for beef cattle
author MacNeil,Michael D.
author_facet MacNeil,Michael D.
author_role author
dc.contributor.author.fl_str_mv MacNeil,Michael D.
dc.subject.por.fl_str_mv animal breeding
assisted selection
genetic gain
production system
topic animal breeding
assisted selection
genetic gain
production system
description ABSTRACT The objective of this research was to discern the contribution of genomic information to multiple-trait breeding objectives and thus understand the economic value of that information. True genetic values were simulated for each of n, possibly correlated, traits. These true genetic values, combined with uncorrelated random noise, resulted in both genomic and phenotypic estimated breeding values, EBVg and EBVp, respectively. The separate EBV were then merged (blended) as a function of their respective accuracies to produce a unified EBV for each of the n traits. Finally, for each simulated animal (N = 10000), the sum of products of economic weights and EBV was calculated to predict the economic value (net merit) of the individual. Accuracies of the EBV for the individual traits and net merit were calculated as correlations between predicted and true values. Predicted responses to selection for individual traits included in the breeding objectives were enhanced from 9% to 76% with the greatest benefit accorded to those economically relevant traits that are recorded after selection decisions are made at one year of age, measured less frequently in national cattle evaluation, or often predicted using information from indicator traits. Combining the EBV to predict net merit for terminal and maternal breeding objectives resulted in predicted increases in selection response due to incorporation of genomic information of 27% and 57%, respectively. The results are interpreted to suggest that the economic benefit to be derived from selection based on a multiple-trait economic breeding objective, which is predicted using genomically enhanced EBV, can substantially exceed the present day cost of genotyping the candidates for selection.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016001200794
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016001200794
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s1806-92902016001200010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Zootecnia
publisher.none.fl_str_mv Sociedade Brasileira de Zootecnia
dc.source.none.fl_str_mv Revista Brasileira de Zootecnia v.45 n.12 2016
reponame:Revista Brasileira de Zootecnia (Online)
instname:Sociedade Brasileira de Zootecnia (SBZ)
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instacron_str SBZ
institution SBZ
reponame_str Revista Brasileira de Zootecnia (Online)
collection Revista Brasileira de Zootecnia (Online)
repository.name.fl_str_mv Revista Brasileira de Zootecnia (Online) - Sociedade Brasileira de Zootecnia (SBZ)
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