Impressão 3D do PLA para aplicações biomédicas

Detalhes bibliográficos
Autor(a) principal: Duarte, Fernando Biancardi
Data de Publicação: 2022
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da UFSCAR
Texto Completo: https://repositorio.ufscar.br/handle/ufscar/16253
Resumo: Currently, additive manufacturing (AM) machines, popularly known as 3D printers, can already be found in the most diverse environments around the world, from industrial facilities, homes, offices, service providers, academic institutions to government and military institutions, including the International Space Station (ISS). In recent years has been an increase in the number of plastics being developed for use in AM, opening space for the advancement of materials to be applied in the medical and biotechnological sector, proving to be a great alternative for the future. One of the techniques used in AM is Fused Deposition Modeling (FDM), where a polymer filament is introduced into the printer and then heated and melted to later be deposited on a construction surface, allowing the fabrication of objects in 3 dimensions. In this sense, the use of biomaterials for medical application built from AM technologies becomes an alternative. Therefore, the objective of this work was to carry out a literature review on the main advances and challenges in the areas of tissue engineering and regenerative medicine, through the manufacture of devices using biopolymers, through the additive manufacturing process. For this, the methodology was based on the Systematic Literature Review protocol, through the definition of the database to be explored, the research themes, the strings used for the search and the temporal delimitation of the research. As a result, it was possible to analyze the progress of the study on the subject, with the volume of publications increasing each year. In addition, it was also possible to verify the most promising polymers, considering the relations between their properties and applications, as well as the main challenges for practical application in a viable way.
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spelling Duarte, Fernando BiancardiMarini, Julianohttp://lattes.cnpq.br/453361025504765460850d4c-433b-414a-8f34-ed0141fa191f2022-06-08T19:32:16Z2022-06-08T19:32:16Z2022-04-20DUARTE, Fernando Biancardi. Impressão 3D do PLA para aplicações biomédicas. 2022. Trabalho de Conclusão de Curso (Graduação em Engenharia de Materiais) – Universidade Federal de São Carlos, São Carlos, 2022. Disponível em: https://repositorio.ufscar.br/handle/ufscar/16253.https://repositorio.ufscar.br/handle/ufscar/16253Currently, additive manufacturing (AM) machines, popularly known as 3D printers, can already be found in the most diverse environments around the world, from industrial facilities, homes, offices, service providers, academic institutions to government and military institutions, including the International Space Station (ISS). In recent years has been an increase in the number of plastics being developed for use in AM, opening space for the advancement of materials to be applied in the medical and biotechnological sector, proving to be a great alternative for the future. One of the techniques used in AM is Fused Deposition Modeling (FDM), where a polymer filament is introduced into the printer and then heated and melted to later be deposited on a construction surface, allowing the fabrication of objects in 3 dimensions. In this sense, the use of biomaterials for medical application built from AM technologies becomes an alternative. Therefore, the objective of this work was to carry out a literature review on the main advances and challenges in the areas of tissue engineering and regenerative medicine, through the manufacture of devices using biopolymers, through the additive manufacturing process. For this, the methodology was based on the Systematic Literature Review protocol, through the definition of the database to be explored, the research themes, the strings used for the search and the temporal delimitation of the research. As a result, it was possible to analyze the progress of the study on the subject, with the volume of publications increasing each year. In addition, it was also possible to verify the most promising polymers, considering the relations between their properties and applications, as well as the main challenges for practical application in a viable way.Atualmente, as máquinas de manufatura aditiva (AM), popularmente conhecidas como impressoras 3D, já podem ser encontradas nos mais diversos ambientes em todo o mundo, desde instalações industriais, casas, escritórios, prestadores de serviços, instituições acadêmicas até instituições governamentais e militares, incluindo a Estação Espacial Internacional (ISS). Nos últimos anos houve um aumento no número de plásticos sendo desenvolvidos para o uso na AM, abrindo espaço para o avanço de materiais a serem aplicados no setor médico e biotecnológico, mostrando-se como uma grande alternativa para o futuro. Uma das técnicas utilizadas na AM é a modelagem por deposição de fundido (FDM), onde um filamento de polímero é introduzido na impressora e então aquecido e fundido para posteriormente ser depositado em uma superfície de construção, permitindo a fabricação de objetos em 3 dimensões. Neste sentido, a utilização de biomateriais para aplicação médica construídos a partir de tecnologias de AM, se tornam uma alternativa. Portanto, o objetivo deste trabalho foi realizar uma revisão bibliográfica sobre os principais avanços e desafios nas áreas de engenharia de tecidos e medicina regenerativa, por meio da fabricação de dispositivos utilizando biopolímeros, através do processo de manufatura aditiva. Para isto, a metodologia foi baseada no protocolo de Revisão Bibliográfica Sistemática, por meio da definição da base de dados a ser explorada, dos temas da pesquisa, das strings utilizadas para a busca e da delimitação temporal da pesquisa. Como resultados, foi possível analisar o avanço do estudo sobre o tema, com o volume de publicações crescente a cada ano. Além disso, também foi possível constatar os polímeros mais promissores, considerando a relação entre suas propriedades e aplicações, bem como os principais desafios para a aplicação prática de maneira viável.Não recebi financiamentoporUniversidade Federal de São CarlosCâmpus São CarlosEngenharia de Materiais - EMaUFSCarAttribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessEngenharia de tecidosImpressão 3DBiopolímerosPolímeros biocompatíveisPLAPLGATissue engineering3D printingBiopolymersBiocompatible polymersENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOSENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOS::POLIMEROS, APLICACOESImpressão 3D do PLA para aplicações biomédicas3D printing of PLA for biomedical applicationsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesis60060063f6b8be-2951-461f-ad9a-61bf65052b40reponame:Repositório Institucional da UFSCARinstname:Universidade Federal de São Carlos (UFSCAR)instacron:UFSCARORIGINALFernando Biancardi Duarte.pdfFernando Biancardi Duarte.pdfapplication/pdf735634https://repositorio.ufscar.br/bitstream/ufscar/16253/1/Fernando%20Biancardi%20Duarte.pdf79dbfa889ed469e2a161b691ebc29d40MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8811https://repositorio.ufscar.br/bitstream/ufscar/16253/2/license_rdfe39d27027a6cc9cb039ad269a5db8e34MD52TEXTFernando Biancardi Duarte.pdf.txtFernando Biancardi Duarte.pdf.txtExtracted texttext/plain47772https://repositorio.ufscar.br/bitstream/ufscar/16253/3/Fernando%20Biancardi%20Duarte.pdf.txte18977168aece6aeb2b7c6170d1c6b46MD53THUMBNAILFernando Biancardi Duarte.pdf.jpgFernando Biancardi Duarte.pdf.jpgIM Thumbnailimage/jpeg6270https://repositorio.ufscar.br/bitstream/ufscar/16253/4/Fernando%20Biancardi%20Duarte.pdf.jpgae3c4c28c60e2f8172f733a307a866e5MD54ufscar/162532023-09-18 18:32:19.873oai:repositorio.ufscar.br:ufscar/16253Repositório InstitucionalPUBhttps://repositorio.ufscar.br/oai/requestopendoar:43222023-09-18T18:32:19Repositório Institucional da UFSCAR - Universidade Federal de São Carlos (UFSCAR)false
dc.title.por.fl_str_mv Impressão 3D do PLA para aplicações biomédicas
dc.title.alternative.eng.fl_str_mv 3D printing of PLA for biomedical applications
title Impressão 3D do PLA para aplicações biomédicas
spellingShingle Impressão 3D do PLA para aplicações biomédicas
Duarte, Fernando Biancardi
Engenharia de tecidos
Impressão 3D
Biopolímeros
Polímeros biocompatíveis
PLA
PLGA
Tissue engineering
3D printing
Biopolymers
Biocompatible polymers
ENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOS
ENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOS::POLIMEROS, APLICACOES
title_short Impressão 3D do PLA para aplicações biomédicas
title_full Impressão 3D do PLA para aplicações biomédicas
title_fullStr Impressão 3D do PLA para aplicações biomédicas
title_full_unstemmed Impressão 3D do PLA para aplicações biomédicas
title_sort Impressão 3D do PLA para aplicações biomédicas
author Duarte, Fernando Biancardi
author_facet Duarte, Fernando Biancardi
author_role author
dc.contributor.author.fl_str_mv Duarte, Fernando Biancardi
dc.contributor.advisor1.fl_str_mv Marini, Juliano
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/4533610255047654
dc.contributor.authorID.fl_str_mv 60850d4c-433b-414a-8f34-ed0141fa191f
contributor_str_mv Marini, Juliano
dc.subject.por.fl_str_mv Engenharia de tecidos
Impressão 3D
Biopolímeros
Polímeros biocompatíveis
PLA
PLGA
topic Engenharia de tecidos
Impressão 3D
Biopolímeros
Polímeros biocompatíveis
PLA
PLGA
Tissue engineering
3D printing
Biopolymers
Biocompatible polymers
ENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOS
ENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOS::POLIMEROS, APLICACOES
dc.subject.eng.fl_str_mv Tissue engineering
3D printing
Biopolymers
Biocompatible polymers
dc.subject.cnpq.fl_str_mv ENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOS
ENGENHARIAS::ENGENHARIA DE MATERIAIS E METALURGICA::MATERIAIS NAO METALICOS::POLIMEROS, APLICACOES
description Currently, additive manufacturing (AM) machines, popularly known as 3D printers, can already be found in the most diverse environments around the world, from industrial facilities, homes, offices, service providers, academic institutions to government and military institutions, including the International Space Station (ISS). In recent years has been an increase in the number of plastics being developed for use in AM, opening space for the advancement of materials to be applied in the medical and biotechnological sector, proving to be a great alternative for the future. One of the techniques used in AM is Fused Deposition Modeling (FDM), where a polymer filament is introduced into the printer and then heated and melted to later be deposited on a construction surface, allowing the fabrication of objects in 3 dimensions. In this sense, the use of biomaterials for medical application built from AM technologies becomes an alternative. Therefore, the objective of this work was to carry out a literature review on the main advances and challenges in the areas of tissue engineering and regenerative medicine, through the manufacture of devices using biopolymers, through the additive manufacturing process. For this, the methodology was based on the Systematic Literature Review protocol, through the definition of the database to be explored, the research themes, the strings used for the search and the temporal delimitation of the research. As a result, it was possible to analyze the progress of the study on the subject, with the volume of publications increasing each year. In addition, it was also possible to verify the most promising polymers, considering the relations between their properties and applications, as well as the main challenges for practical application in a viable way.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-06-08T19:32:16Z
dc.date.available.fl_str_mv 2022-06-08T19:32:16Z
dc.date.issued.fl_str_mv 2022-04-20
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dc.identifier.citation.fl_str_mv DUARTE, Fernando Biancardi. Impressão 3D do PLA para aplicações biomédicas. 2022. Trabalho de Conclusão de Curso (Graduação em Engenharia de Materiais) – Universidade Federal de São Carlos, São Carlos, 2022. Disponível em: https://repositorio.ufscar.br/handle/ufscar/16253.
dc.identifier.uri.fl_str_mv https://repositorio.ufscar.br/handle/ufscar/16253
identifier_str_mv DUARTE, Fernando Biancardi. Impressão 3D do PLA para aplicações biomédicas. 2022. Trabalho de Conclusão de Curso (Graduação em Engenharia de Materiais) – Universidade Federal de São Carlos, São Carlos, 2022. Disponível em: https://repositorio.ufscar.br/handle/ufscar/16253.
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Câmpus São Carlos
Engenharia de Materiais - EMa
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Câmpus São Carlos
Engenharia de Materiais - EMa
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