Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae)
Autor(a) principal: | |
---|---|
Data de Publicação: | 2006 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFSCAR |
Texto Completo: | https://repositorio.ufscar.br/handle/ufscar/6083 |
Resumo: | This work describes the results of the search for insecticidal compounds from the Meliaceae family. The samples assayed against fall armyworm Spodoptera frugiperda were the hexane, methanol and hydromethanol extracts of twigs, leaves, seeds, aril and exocarp of T. catigua; twigs, leaves, fruits, seeds, aril and exocarp of T. claussenii and twigs, leaves and fruits of T. elegans. The hexane and methanol extracts of leaves, hexane of twigs and methanol of fruits from T. claussenii showed to possess the higher insecticidal activity against S. frugiperda. Nevertheless, the hexane and methanol extracts of fruits from T. elegans showed the highest rate of larval mortality (100 %). The hydromethanol extract of T. elegans showed moderate insecticidal activity and also showed growth inhibition and antifeedant activities. The active extracts were fractionated and the chemical study led to isolation of 20 compounds, including limonoids, triterpenes, coumarins, steroids and one sesquiterpene. From the hexane extract of leaves from T. claussenii were isolated the steroids β-sitosterol, stigmasterol, campesterol and sitostenone; the triterpenoids α-amyrin, β-amyrin, lupeol, lupenone, in addition to the cycloartane triterpene 24-methylen-26- hydroxycicloartan-3-on and sesquiterpene criptomeridiol. From the methanol extract of leaves of T. claussenii were isolated the steroids 24-methylen-3 β,4 β,22 α- trihydroxy-colesterol and 3- β-O- β-D-glucopyranosilsitosterol. From the methanol extract of fruits from T. elegans were isolated the coumarins 6,7- dimethoxycoumarin, 6-methoxy-7-hydroxycoumarin e 7-hydroxycoumarin. The same coumarins and the steroids were also isolated from the hexane extract of fruits from T. elegans. The limonoids cedrelone and 11 β-methoxycedrelone were isolated from the hexane extract of aril from T. catigua. Limonoids methylangolensate together with the photogedunin epimeric mixture were isolated from the methanol extract of aril from T. catigua. This is first report of the isolation of limonoids from T. catigua. Triterpens isolated from Cedrela fissilis and limonoids isolated from Cipadessa fruticosa (Meliaceae) were tested against S. frugiperda. Among them odoratol showed the best results (insecticidal activity, growth inhibition and antifeedant). Febrifugin A showed the highest rate of mortality of total cycle (at 50 mg kg-1) of 73.3%. |
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Matos, Andréia PereiraFernandes, João Batistahttp://genos.cnpq.br:12010/dwlattes/owa/prc_imp_cv_int?f_cod=K4787151T1http://lattes.cnpq.br/615520294008769674c28e41-e1bd-4f35-8d1e-5f0950983f092016-06-02T20:34:05Z2007-08-012016-06-02T20:34:05Z2006-05-15MATOS, Andréia Pereira. Search of insecticidal compounds - study of species from the genus Trichilia (Meliaceae). 2006. 194 f. Tese (Doutorado em Ciências Exatas e da Terra) - Universidade Federal de São Carlos, São Carlos, 2006.https://repositorio.ufscar.br/handle/ufscar/6083This work describes the results of the search for insecticidal compounds from the Meliaceae family. The samples assayed against fall armyworm Spodoptera frugiperda were the hexane, methanol and hydromethanol extracts of twigs, leaves, seeds, aril and exocarp of T. catigua; twigs, leaves, fruits, seeds, aril and exocarp of T. claussenii and twigs, leaves and fruits of T. elegans. The hexane and methanol extracts of leaves, hexane of twigs and methanol of fruits from T. claussenii showed to possess the higher insecticidal activity against S. frugiperda. Nevertheless, the hexane and methanol extracts of fruits from T. elegans showed the highest rate of larval mortality (100 %). The hydromethanol extract of T. elegans showed moderate insecticidal activity and also showed growth inhibition and antifeedant activities. The active extracts were fractionated and the chemical study led to isolation of 20 compounds, including limonoids, triterpenes, coumarins, steroids and one sesquiterpene. From the hexane extract of leaves from T. claussenii were isolated the steroids β-sitosterol, stigmasterol, campesterol and sitostenone; the triterpenoids α-amyrin, β-amyrin, lupeol, lupenone, in addition to the cycloartane triterpene 24-methylen-26- hydroxycicloartan-3-on and sesquiterpene criptomeridiol. From the methanol extract of leaves of T. claussenii were isolated the steroids 24-methylen-3 β,4 β,22 α- trihydroxy-colesterol and 3- β-O- β-D-glucopyranosilsitosterol. From the methanol extract of fruits from T. elegans were isolated the coumarins 6,7- dimethoxycoumarin, 6-methoxy-7-hydroxycoumarin e 7-hydroxycoumarin. The same coumarins and the steroids were also isolated from the hexane extract of fruits from T. elegans. The limonoids cedrelone and 11 β-methoxycedrelone were isolated from the hexane extract of aril from T. catigua. Limonoids methylangolensate together with the photogedunin epimeric mixture were isolated from the methanol extract of aril from T. catigua. This is first report of the isolation of limonoids from T. catigua. Triterpens isolated from Cedrela fissilis and limonoids isolated from Cipadessa fruticosa (Meliaceae) were tested against S. frugiperda. Among them odoratol showed the best results (insecticidal activity, growth inhibition and antifeedant). Febrifugin A showed the highest rate of mortality of total cycle (at 50 mg kg-1) of 73.3%.Este trabalho apresenta os resultados obtidos dos ensaios biológicos dos extratos hexânico, metanólico e hidrometanólico de ramos, folhas, sementes, arilo e exocarpo de T. catigua; ramos, folhas, frutos, sementes, arilo e exocarpo de T. claussenii e ramos, folhas e sementes de T. elegans sobre à lagarta-do-cartucho do milho Spodoptera frugiperda. Os extratos hexânico e metanólico de folhas, hexânico de ramos e metanólico de frutos de T. claussenii apresentaram alta atividade inseticida frente a S. frugiperda. No entanto, os extratos hexânico e metanólico de frutos de T. elegans causaram a mais alta taxa de mortalidade larval (100 %), já o extrato hidrometanólico apresentou atividade inseticida moderada e mostrou-se inibidor de crescimento e da alimentação. Os extratos ativos foram fracionados e o estudo químico levou ao isolamento de 20 metabólitos, incluindo limonóides, triterpenos, cumarinas, esteróides e um sesquiterpeno. Do extrato hexânico de folhas de T. claussenii foram isolados os esteróides β-sitosterol, estigmasterol, campesterol, sitostenona e os triterpenóides α-amirina, β-amirina, lupeol, lupenona, além do triterpeno do tipo cicloartano 24-metileno-26-hidroxicicloartan-3-ona e do sesquiterpeno criptomeridiol. Do extrato metanólico de folhas de T. claussenii foram isolados somente os esteróides 24-metileno-3 β,4 β,22 α-triidroxi-colesterol e - β-O- β-Dglucopiranosil sitosterol. Ao se fracionar o extrato metanólico de frutos de T. elegans foram isoladas as cumarinas 6,7-dimetoxicumarina, 6-metoxi-7- hidroxicumarina e 7-hidroxicumarina. As mesmas cumarinas e os esteróides foram novamente isolados do extrato hexânico de frutos de T. elegans. Os limonóides cedrelona e 11β-metoxicedrelona foram isolados do extrato hexânico do arilo de T. catigua. Além destes limonóides, o angolensato de metila e a mistura epimérica de fotogedunina foram isolados do extrato metanólico do arilo de T. catigua. Este é o primeiro relato do isolamento de limonóides de T. catigua. Triterpenóides isolados de Cedrela fissilis e limonóides isolados de Cipadessa fruticosa (Meliaceae) foram ensaiados frente a S. frugiperda. Dentre os triterpenóides testados, o odoratol apresentou os melhores resultados (atividade inseticida, inibidor de crescimento e inibidor de alimentação). A febrifugina A causou a mais alta taxa de mortalidade do ciclo total (a 50 mg kg-1) de 73,3%.application/pdfporUniversidade Federal de São CarlosPrograma de Pós-Graduação em Química - PPGQUFSCarBRProdutos naturaisTrichiliaInseticidas vegetaisSpodoptera frugiperdaMeliaceaeCIENCIAS EXATAS E DA TERRA::QUIMICABusca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae)Search of insecticidal compounds: study of species from the genus Trichilia (Meliaceae)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis-1-1f08d89b4-2b31-4e90-9be7-b86a7c15645cinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSCARinstname:Universidade Federal de São Carlos (UFSCAR)instacron:UFSCARORIGINALTeseAPM.pdfapplication/pdf3545061https://repositorio.ufscar.br/bitstream/ufscar/6083/1/TeseAPM.pdf5ef30df4bdf3fc845cd85984795b7e0cMD51THUMBNAILTeseAPM.pdf.jpgTeseAPM.pdf.jpgIM Thumbnailimage/jpeg8434https://repositorio.ufscar.br/bitstream/ufscar/6083/2/TeseAPM.pdf.jpg6b899f644e95c81095713e3e94d3a017MD52ufscar/60832023-09-18 18:31:10.57oai:repositorio.ufscar.br:ufscar/6083Repositório InstitucionalPUBhttps://repositorio.ufscar.br/oai/requestopendoar:43222023-09-18T18:31:10Repositório Institucional da UFSCAR - Universidade Federal de São Carlos (UFSCAR)false |
dc.title.por.fl_str_mv |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) |
dc.title.alternative.eng.fl_str_mv |
Search of insecticidal compounds: study of species from the genus Trichilia (Meliaceae) |
title |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) |
spellingShingle |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) Matos, Andréia Pereira Produtos naturais Trichilia Inseticidas vegetais Spodoptera frugiperda Meliaceae CIENCIAS EXATAS E DA TERRA::QUIMICA |
title_short |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) |
title_full |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) |
title_fullStr |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) |
title_full_unstemmed |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) |
title_sort |
Busca de compostos inseticidas: estudo de espécies do gênero Trichilia (Meliaceae) |
author |
Matos, Andréia Pereira |
author_facet |
Matos, Andréia Pereira |
author_role |
author |
dc.contributor.authorlattes.por.fl_str_mv |
http://lattes.cnpq.br/6155202940087696 |
dc.contributor.author.fl_str_mv |
Matos, Andréia Pereira |
dc.contributor.advisor1.fl_str_mv |
Fernandes, João Batista |
dc.contributor.advisor1Lattes.fl_str_mv |
http://genos.cnpq.br:12010/dwlattes/owa/prc_imp_cv_int?f_cod=K4787151T1 |
dc.contributor.authorID.fl_str_mv |
74c28e41-e1bd-4f35-8d1e-5f0950983f09 |
contributor_str_mv |
Fernandes, João Batista |
dc.subject.por.fl_str_mv |
Produtos naturais Trichilia Inseticidas vegetais Spodoptera frugiperda Meliaceae |
topic |
Produtos naturais Trichilia Inseticidas vegetais Spodoptera frugiperda Meliaceae CIENCIAS EXATAS E DA TERRA::QUIMICA |
dc.subject.cnpq.fl_str_mv |
CIENCIAS EXATAS E DA TERRA::QUIMICA |
description |
This work describes the results of the search for insecticidal compounds from the Meliaceae family. The samples assayed against fall armyworm Spodoptera frugiperda were the hexane, methanol and hydromethanol extracts of twigs, leaves, seeds, aril and exocarp of T. catigua; twigs, leaves, fruits, seeds, aril and exocarp of T. claussenii and twigs, leaves and fruits of T. elegans. The hexane and methanol extracts of leaves, hexane of twigs and methanol of fruits from T. claussenii showed to possess the higher insecticidal activity against S. frugiperda. Nevertheless, the hexane and methanol extracts of fruits from T. elegans showed the highest rate of larval mortality (100 %). The hydromethanol extract of T. elegans showed moderate insecticidal activity and also showed growth inhibition and antifeedant activities. The active extracts were fractionated and the chemical study led to isolation of 20 compounds, including limonoids, triterpenes, coumarins, steroids and one sesquiterpene. From the hexane extract of leaves from T. claussenii were isolated the steroids β-sitosterol, stigmasterol, campesterol and sitostenone; the triterpenoids α-amyrin, β-amyrin, lupeol, lupenone, in addition to the cycloartane triterpene 24-methylen-26- hydroxycicloartan-3-on and sesquiterpene criptomeridiol. From the methanol extract of leaves of T. claussenii were isolated the steroids 24-methylen-3 β,4 β,22 α- trihydroxy-colesterol and 3- β-O- β-D-glucopyranosilsitosterol. From the methanol extract of fruits from T. elegans were isolated the coumarins 6,7- dimethoxycoumarin, 6-methoxy-7-hydroxycoumarin e 7-hydroxycoumarin. The same coumarins and the steroids were also isolated from the hexane extract of fruits from T. elegans. The limonoids cedrelone and 11 β-methoxycedrelone were isolated from the hexane extract of aril from T. catigua. Limonoids methylangolensate together with the photogedunin epimeric mixture were isolated from the methanol extract of aril from T. catigua. This is first report of the isolation of limonoids from T. catigua. Triterpens isolated from Cedrela fissilis and limonoids isolated from Cipadessa fruticosa (Meliaceae) were tested against S. frugiperda. Among them odoratol showed the best results (insecticidal activity, growth inhibition and antifeedant). Febrifugin A showed the highest rate of mortality of total cycle (at 50 mg kg-1) of 73.3%. |
publishDate |
2006 |
dc.date.issued.fl_str_mv |
2006-05-15 |
dc.date.available.fl_str_mv |
2007-08-01 2016-06-02T20:34:05Z |
dc.date.accessioned.fl_str_mv |
2016-06-02T20:34:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MATOS, Andréia Pereira. Search of insecticidal compounds - study of species from the genus Trichilia (Meliaceae). 2006. 194 f. Tese (Doutorado em Ciências Exatas e da Terra) - Universidade Federal de São Carlos, São Carlos, 2006. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufscar.br/handle/ufscar/6083 |
identifier_str_mv |
MATOS, Andréia Pereira. Search of insecticidal compounds - study of species from the genus Trichilia (Meliaceae). 2006. 194 f. Tese (Doutorado em Ciências Exatas e da Terra) - Universidade Federal de São Carlos, São Carlos, 2006. |
url |
https://repositorio.ufscar.br/handle/ufscar/6083 |
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por |
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openAccess |
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Universidade Federal de São Carlos |
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Programa de Pós-Graduação em Química - PPGQ |
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UFSCar |
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BR |
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Universidade Federal de São Carlos |
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