Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFSCAR |
Texto Completo: | https://repositorio.ufscar.br/handle/ufscar/5322 |
Resumo: | Background: Sickle Cell Disease (SCD) is characterized by a genetic mutation in beta hemoglobin chain, causing dysfunctions in the body, such as pulmonary function and functional capacity. Objective: To assessment the changes in pulmonary function and functional capacity in patients with sickle cell disease, as well as identify the relationship between these variables. Methods: Descriptive transversal study, exploratory and quantitative methodology, in which 21 subjects with sickle cell disease were evaluated (29±6 years), regarding sociodemographic, anthropometric, lung function (spirometry), respiratory (manovacuometer) and peripheral (Handgrip strength - HS) muscle strength and functional capacity (six-minute walk test - 6MWT). Proceeded to statistical analysis using the Shapiro-Wilk test, Paired t Student, Wilcoxon, Pearson and Spearman correlation (p<0.05). Results: It was observed changes in pulmonary function in 47.6% of subjects, 42.8% had a restrictive ventilatory pattern (RVP) and 4.8% had mixed ventilatory pattern. Maximal inspiratory pressure (MIP) presented predicted value below for women (obtained: 64±13cmH2O/ predicted: 93±2cmH2O) and maximum expiratory pressure (MEP), HS and distance walked during 6MWT had values below of predicted for men (obtained values: 103±27cmH2O; 39±7Kgf; 447±62m and predicted values: 143±5cmH2O; 45±1Kgf; 731±61m, respectively) and women (obtained values: 64±17cmH2O; 27±7Kgf; 405±71m and predicted values: 94±2cmH2O; 33±1Kgf; 683±30m, respectively). Positive correlations was observed of maximum voluntary ventilation (MVV) with MEP (r = 0.4; p=0.046) and body mass index (BMI) (r = 0.6; p=0.003); and HS with MIP (r = 0.7; p=0.001), MEP (r = 0.6; p=0.002), MVV (r = 0.5; p=0.015), distance walked in 6MWT (r = 0.4; p=0.038) and BMI (r=0.6; p=0.004). Conclusion: DF promoted changes in lung function and functional capacity, which predominated a RVP and reduced tolerance to physical exertion. In addition, these variables correlated with each other. |
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Ohara, Daniela GonçalvesJamami, Mauríciohttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=E463020http://lattes.cnpq.br/9253801829027802cca78b21-d268-45fa-a97c-1d030291fbbe2016-06-02T20:19:22Z2014-02-282016-06-02T20:19:22Z2014-02-20OHARA, Daniela Gonçalves. Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme. 2014. 53 f. Dissertação (Mestrado em Ciências Biológicas) - Universidade Federal de São Carlos, São Carlos, 2014.https://repositorio.ufscar.br/handle/ufscar/5322Background: Sickle Cell Disease (SCD) is characterized by a genetic mutation in beta hemoglobin chain, causing dysfunctions in the body, such as pulmonary function and functional capacity. Objective: To assessment the changes in pulmonary function and functional capacity in patients with sickle cell disease, as well as identify the relationship between these variables. Methods: Descriptive transversal study, exploratory and quantitative methodology, in which 21 subjects with sickle cell disease were evaluated (29±6 years), regarding sociodemographic, anthropometric, lung function (spirometry), respiratory (manovacuometer) and peripheral (Handgrip strength - HS) muscle strength and functional capacity (six-minute walk test - 6MWT). Proceeded to statistical analysis using the Shapiro-Wilk test, Paired t Student, Wilcoxon, Pearson and Spearman correlation (p<0.05). Results: It was observed changes in pulmonary function in 47.6% of subjects, 42.8% had a restrictive ventilatory pattern (RVP) and 4.8% had mixed ventilatory pattern. Maximal inspiratory pressure (MIP) presented predicted value below for women (obtained: 64±13cmH2O/ predicted: 93±2cmH2O) and maximum expiratory pressure (MEP), HS and distance walked during 6MWT had values below of predicted for men (obtained values: 103±27cmH2O; 39±7Kgf; 447±62m and predicted values: 143±5cmH2O; 45±1Kgf; 731±61m, respectively) and women (obtained values: 64±17cmH2O; 27±7Kgf; 405±71m and predicted values: 94±2cmH2O; 33±1Kgf; 683±30m, respectively). Positive correlations was observed of maximum voluntary ventilation (MVV) with MEP (r = 0.4; p=0.046) and body mass index (BMI) (r = 0.6; p=0.003); and HS with MIP (r = 0.7; p=0.001), MEP (r = 0.6; p=0.002), MVV (r = 0.5; p=0.015), distance walked in 6MWT (r = 0.4; p=0.038) and BMI (r=0.6; p=0.004). Conclusion: DF promoted changes in lung function and functional capacity, which predominated a RVP and reduced tolerance to physical exertion. In addition, these variables correlated with each other.Contextualização: A Doença Falciforme (DF) caracteriza-se por mutação genética na cadeia beta da hemoglobina, gerando disfunções no organismo, como comprometimento da função pulmonar e da capacidade funcional. Objetivos: Avaliar as alterações da função pulmonar e da capacidade funcional de indivíduos com DF, assim como identificar a relação entre essas variáveis. Métodos: Estudo descritivo, transversal, de caráter exploratório e metodologia quantitativa, no qual foram avaliados 21 indivíduos com DF (29±6 anos), segundo aspectos sociodemográficos, antropométricos, função pulmonar (espirometria), força muscular respiratória (manovacuometria) e periférica (força de preensão palmar - FPP) e capacidade funcional (teste de caminhada de seis minutos - TC6). Procedeu-se à análise estatística com os testes Shapiro-Wilk, t de Student pareado, Wilcoxon, correlação de Pearson e Spearman (p<0,05). Resultados: Observou-se alteração da função pulmonar em 47,6% dos indivíduos, sendo 42,8% com padrão ventilatório restritivo (PVR) e 4,8% padrão ventilatório misto. A pressão inspiratória máxima (PImáx) apresentou valor abaixo do previsto somente para as mulheres (obtido: 64±13cmH2O/ previsto: 93±2cmH2O), enquanto a pressão expiratória máxima (PEmáx), a FPP e a distância percorrida no TC6 apresentaram valores abaixo do previsto tanto para homens (valores obtidos: 103±27cmH2O; 39±7Kgf; 447±62m e valores previstos: 143±5cmH2O; 45±1Kgf; 731±61m, respectivamente) quanto para as mulheres (valores obtidos: 64±17cmH2O; 27±7Kgf; 405±71m e valores previstos: 94±2cmH2O; 33±1Kgf; 683±30m, respectivamente). Observaram-se correlações positivas da ventilação voluntária máxima (VVM) com a PEmáx (r=0,4; p=0,046) e índice de massa corporal (IMC) (r=0,6; p=0,003); e da FPP com a PImáx (r=0,7; p=0,001), PEmáx (r=0,6; p=0,002), VVM (r=0,5; p=0,015), distância percorrida no TC6 (r=0,4; p=0,038) e IMC (r=0,6; p=0,004). Conclusão: A DF promoveu alterações na função pulmonar e na capacidade funcional, havendo predominância do PVR e redução da tolerância aos esforços físicos. Além disso, essas variáveis apresentaram correlação entre si.Financiadora de Estudos e Projetosapplication/pdfporUniversidade Federal de São CarlosPrograma de Pós-Graduação em Fisioterapia - PPGFtUFSCarBRFisioterapiaAnemia falciformeTestes da função respiratóriaEspirometriaTeste de caminhadaSickle cell anemiaPhysical therapy specialtyRespiratory function testsSpirometryWalkingCIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONALFunção pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciformeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-1-1bd0cbb98-978e-41d4-acd9-a1acaba0dedainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSCARinstname:Universidade Federal de São Carlos (UFSCAR)instacron:UFSCARORIGINAL5746.pdfapplication/pdf1041939https://repositorio.ufscar.br/bitstream/ufscar/5322/1/5746.pdfb8d3091d836cd0fc85f86f1628bc4e8cMD51TEXT5746.pdf.txt5746.pdf.txtExtracted texttext/plain0https://repositorio.ufscar.br/bitstream/ufscar/5322/2/5746.pdf.txtd41d8cd98f00b204e9800998ecf8427eMD52THUMBNAIL5746.pdf.jpg5746.pdf.jpgIM Thumbnailimage/jpeg5372https://repositorio.ufscar.br/bitstream/ufscar/5322/3/5746.pdf.jpgdbaca627c34e55f3d21ccb3d35f49248MD53ufscar/53222023-09-18 18:31:35.915oai:repositorio.ufscar.br:ufscar/5322Repositório InstitucionalPUBhttps://repositorio.ufscar.br/oai/requestopendoar:43222023-09-18T18:31:35Repositório Institucional da UFSCAR - Universidade Federal de São Carlos (UFSCAR)false |
dc.title.por.fl_str_mv |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme |
title |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme |
spellingShingle |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme Ohara, Daniela Gonçalves Fisioterapia Anemia falciforme Testes da função respiratória Espirometria Teste de caminhada Sickle cell anemia Physical therapy specialty Respiratory function tests Spirometry Walking CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL |
title_short |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme |
title_full |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme |
title_fullStr |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme |
title_full_unstemmed |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme |
title_sort |
Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme |
author |
Ohara, Daniela Gonçalves |
author_facet |
Ohara, Daniela Gonçalves |
author_role |
author |
dc.contributor.authorlattes.por.fl_str_mv |
http://lattes.cnpq.br/9253801829027802 |
dc.contributor.author.fl_str_mv |
Ohara, Daniela Gonçalves |
dc.contributor.advisor1.fl_str_mv |
Jamami, Maurício |
dc.contributor.advisor1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=E463020 |
dc.contributor.authorID.fl_str_mv |
cca78b21-d268-45fa-a97c-1d030291fbbe |
contributor_str_mv |
Jamami, Maurício |
dc.subject.por.fl_str_mv |
Fisioterapia Anemia falciforme Testes da função respiratória Espirometria Teste de caminhada |
topic |
Fisioterapia Anemia falciforme Testes da função respiratória Espirometria Teste de caminhada Sickle cell anemia Physical therapy specialty Respiratory function tests Spirometry Walking CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL |
dc.subject.eng.fl_str_mv |
Sickle cell anemia Physical therapy specialty Respiratory function tests Spirometry Walking |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL |
description |
Background: Sickle Cell Disease (SCD) is characterized by a genetic mutation in beta hemoglobin chain, causing dysfunctions in the body, such as pulmonary function and functional capacity. Objective: To assessment the changes in pulmonary function and functional capacity in patients with sickle cell disease, as well as identify the relationship between these variables. Methods: Descriptive transversal study, exploratory and quantitative methodology, in which 21 subjects with sickle cell disease were evaluated (29±6 years), regarding sociodemographic, anthropometric, lung function (spirometry), respiratory (manovacuometer) and peripheral (Handgrip strength - HS) muscle strength and functional capacity (six-minute walk test - 6MWT). Proceeded to statistical analysis using the Shapiro-Wilk test, Paired t Student, Wilcoxon, Pearson and Spearman correlation (p<0.05). Results: It was observed changes in pulmonary function in 47.6% of subjects, 42.8% had a restrictive ventilatory pattern (RVP) and 4.8% had mixed ventilatory pattern. Maximal inspiratory pressure (MIP) presented predicted value below for women (obtained: 64±13cmH2O/ predicted: 93±2cmH2O) and maximum expiratory pressure (MEP), HS and distance walked during 6MWT had values below of predicted for men (obtained values: 103±27cmH2O; 39±7Kgf; 447±62m and predicted values: 143±5cmH2O; 45±1Kgf; 731±61m, respectively) and women (obtained values: 64±17cmH2O; 27±7Kgf; 405±71m and predicted values: 94±2cmH2O; 33±1Kgf; 683±30m, respectively). Positive correlations was observed of maximum voluntary ventilation (MVV) with MEP (r = 0.4; p=0.046) and body mass index (BMI) (r = 0.6; p=0.003); and HS with MIP (r = 0.7; p=0.001), MEP (r = 0.6; p=0.002), MVV (r = 0.5; p=0.015), distance walked in 6MWT (r = 0.4; p=0.038) and BMI (r=0.6; p=0.004). Conclusion: DF promoted changes in lung function and functional capacity, which predominated a RVP and reduced tolerance to physical exertion. In addition, these variables correlated with each other. |
publishDate |
2014 |
dc.date.available.fl_str_mv |
2014-02-28 2016-06-02T20:19:22Z |
dc.date.issued.fl_str_mv |
2014-02-20 |
dc.date.accessioned.fl_str_mv |
2016-06-02T20:19:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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masterThesis |
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dc.identifier.citation.fl_str_mv |
OHARA, Daniela Gonçalves. Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme. 2014. 53 f. Dissertação (Mestrado em Ciências Biológicas) - Universidade Federal de São Carlos, São Carlos, 2014. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufscar.br/handle/ufscar/5322 |
identifier_str_mv |
OHARA, Daniela Gonçalves. Função pulmonar e teste de caminhada de seis minutos em indivíduos com doença falciforme. 2014. 53 f. Dissertação (Mestrado em Ciências Biológicas) - Universidade Federal de São Carlos, São Carlos, 2014. |
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https://repositorio.ufscar.br/handle/ufscar/5322 |
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Universidade Federal de São Carlos |
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