Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly

Detalhes bibliográficos
Autor(a) principal: Soares, Cristiane Regina
Data de Publicação: 2024
Outros Autores: Okuno, Meiry Fernanda Pinto
Tipo de documento: preprint
Idioma: por
Título da fonte: SciELO Preprints
Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/7840
Resumo: Objective: to associate polypharmacy and medication classes with the risk of falls in the elderly. Method: cross-sectional and quantitative study, carried out in a Specialty Medical Outpatient Clinic in the city of São Paulo – SP, with 117 elderly people, from March to November 2019. Data collection was carried out by fully transcribing the prescriptions into an individual form and the Downton Falls Risk Scale. To compare the risk of falls with polypharmacy and medication classes, the Mann-Whitney and Chi-Square tests were used. In all comparative analyzes a significance level of 5% and a confidence interval of 95% were used. Results: The risk of falls showed a significant correlation with the number of medications, an average of 5.8 per day (p<0.0001) and the medication classes, antihypertensives (p<0.0001), oral antidiabetics (p=0.027), diuretics (p<0.0001) and antidepressants (p=0.042). Conclusion and implications for practice: therefore, the importance of evaluating factors related to the increased risk of falls is highlighted, for subsequent planning and implementation of strategies to deal with adverse reactions and the measures to be taken to ensure the effectiveness and safety of drug treatment.
id SCI-1_7bed9dff5f4c13dd9d976b5db99efcec
oai_identifier_str oai:ops.preprints.scielo.org:preprint/7840
network_acronym_str SCI-1
network_name_str SciELO Preprints
repository_id_str
spelling Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderlyImpacto da polifarmácia e o uso de medicamentos associados ao risco de quedas de idososAcidentes por quedasEnvelhecimentoPolimedicaçãoSaúde do idosoAccidental FallsAgingPolypharmacyHealth of the elderlyObjective: to associate polypharmacy and medication classes with the risk of falls in the elderly. Method: cross-sectional and quantitative study, carried out in a Specialty Medical Outpatient Clinic in the city of São Paulo – SP, with 117 elderly people, from March to November 2019. Data collection was carried out by fully transcribing the prescriptions into an individual form and the Downton Falls Risk Scale. To compare the risk of falls with polypharmacy and medication classes, the Mann-Whitney and Chi-Square tests were used. In all comparative analyzes a significance level of 5% and a confidence interval of 95% were used. Results: The risk of falls showed a significant correlation with the number of medications, an average of 5.8 per day (p<0.0001) and the medication classes, antihypertensives (p<0.0001), oral antidiabetics (p=0.027), diuretics (p<0.0001) and antidepressants (p=0.042). Conclusion and implications for practice: therefore, the importance of evaluating factors related to the increased risk of falls is highlighted, for subsequent planning and implementation of strategies to deal with adverse reactions and the measures to be taken to ensure the effectiveness and safety of drug treatment.Objetivo: associar a polifarmácia e as classes medicamentosas com o risco de quedas em idosos. Método: estudo transversal e quantitativo, realizado em um Ambulatório Médico de Especialidades na cidade de São Paulo – SP, com 117 idosos, no período de março a novembro de 2019. A coleta dos dados foi realizada pela transcrição integral dos receituários para um formulário individual e pela Escala de Risco de Quedas de Downton. Para comparar o risco de quedas com a polimedicação e as classes medicamentosas foram utilizados os testes de Mann-Whitney e o Qui-Quadrado. Em todas as análises comparativas foi utilizado um nível de significância de 5% e intervalo de confiança de 95%. Resultados: O risco de quedas apresentou correlação significativa com o número de medicamentos, média de 5,8 ao dia (p<0,0001) e as classes medicamentosas, os anti-hipertensivos (p<0,0001), os antidiabéticos orais (p=0,027), os diuréticos (p<0,0001) e os antidepressivos (p=0,042). Conclusão e implicações para a prática: portanto, ressalta-se a importância da avaliação dos fatores relacionados ao aumento do risco de quedas, para posterior realização de um planejamento e implementação de estratégias no cuidado das reações adversas e nas medidas a serem tomadas para garantir a efetividade e segurança do tratamento medicamentoso.SciELO PreprintsSciELO PreprintsSciELO Preprints2024-01-10info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/784010.1590/SciELOPreprints.7840porhttps://preprints.scielo.org/index.php/scielo/article/view/7840/14674Copyright (c) 2024 Cristiane Regina Soares, Meiry Fernanda Pinto Okunohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSoares, Cristiane ReginaOkuno, Meiry Fernanda Pintoreponame:SciELO Preprintsinstname:Scientific Electronic Library Online (SCIELO)instacron:SCI2024-01-05T00:40:45Zoai:ops.preprints.scielo.org:preprint/7840Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2024-01-05T00:40:45SciELO Preprints - Scientific Electronic Library Online (SCIELO)false
dc.title.none.fl_str_mv Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
Impacto da polifarmácia e o uso de medicamentos associados ao risco de quedas de idosos
title Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
spellingShingle Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
Soares, Cristiane Regina
Acidentes por quedas
Envelhecimento
Polimedicação
Saúde do idoso
Accidental Falls
Aging
Polypharmacy
Health of the elderly
title_short Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
title_full Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
title_fullStr Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
title_full_unstemmed Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
title_sort Impact of polypharmacy and the use of medicines associated with the risk of falls in the elderly
author Soares, Cristiane Regina
author_facet Soares, Cristiane Regina
Okuno, Meiry Fernanda Pinto
author_role author
author2 Okuno, Meiry Fernanda Pinto
author2_role author
dc.contributor.author.fl_str_mv Soares, Cristiane Regina
Okuno, Meiry Fernanda Pinto
dc.subject.por.fl_str_mv Acidentes por quedas
Envelhecimento
Polimedicação
Saúde do idoso
Accidental Falls
Aging
Polypharmacy
Health of the elderly
topic Acidentes por quedas
Envelhecimento
Polimedicação
Saúde do idoso
Accidental Falls
Aging
Polypharmacy
Health of the elderly
description Objective: to associate polypharmacy and medication classes with the risk of falls in the elderly. Method: cross-sectional and quantitative study, carried out in a Specialty Medical Outpatient Clinic in the city of São Paulo – SP, with 117 elderly people, from March to November 2019. Data collection was carried out by fully transcribing the prescriptions into an individual form and the Downton Falls Risk Scale. To compare the risk of falls with polypharmacy and medication classes, the Mann-Whitney and Chi-Square tests were used. In all comparative analyzes a significance level of 5% and a confidence interval of 95% were used. Results: The risk of falls showed a significant correlation with the number of medications, an average of 5.8 per day (p<0.0001) and the medication classes, antihypertensives (p<0.0001), oral antidiabetics (p=0.027), diuretics (p<0.0001) and antidepressants (p=0.042). Conclusion and implications for practice: therefore, the importance of evaluating factors related to the increased risk of falls is highlighted, for subsequent planning and implementation of strategies to deal with adverse reactions and the measures to be taken to ensure the effectiveness and safety of drug treatment.
publishDate 2024
dc.date.none.fl_str_mv 2024-01-10
dc.type.driver.fl_str_mv info:eu-repo/semantics/preprint
info:eu-repo/semantics/publishedVersion
format preprint
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://preprints.scielo.org/index.php/scielo/preprint/view/7840
10.1590/SciELOPreprints.7840
url https://preprints.scielo.org/index.php/scielo/preprint/view/7840
identifier_str_mv 10.1590/SciELOPreprints.7840
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://preprints.scielo.org/index.php/scielo/article/view/7840/14674
dc.rights.driver.fl_str_mv Copyright (c) 2024 Cristiane Regina Soares, Meiry Fernanda Pinto Okuno
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2024 Cristiane Regina Soares, Meiry Fernanda Pinto Okuno
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
dc.source.none.fl_str_mv reponame:SciELO Preprints
instname:Scientific Electronic Library Online (SCIELO)
instacron:SCI
instname_str Scientific Electronic Library Online (SCIELO)
instacron_str SCI
institution SCI
reponame_str SciELO Preprints
collection SciELO Preprints
repository.name.fl_str_mv SciELO Preprints - Scientific Electronic Library Online (SCIELO)
repository.mail.fl_str_mv scielo.submission@scielo.org
_version_ 1797047814723731456

Registros relacionados