MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS

Detalhes bibliográficos
Autor(a) principal: Frugis, Marcos Onofre
Data de Publicação: 2022
Outros Autores: Ribas, Carmen Australia Paredes Marcondes, Malafaia, Osvaldo
Tipo de documento: preprint
Idioma: por
Título da fonte: SciELO Preprints
Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/4130
Resumo: Background: Colorectal cancer (CRC) is among the most common malignancies worldwide. Colonoscopy is the exam of choice for the prevention of CRC due to its great diagnostic and mainly therapeutic capacity in the face of adenomatous lesions. Objective: To analyze the prevalence and the macroscopic and histological characteristics 2 of polypoid rectal lesions resected with endoscopic techniques and to assess whether endoscopic therapy is safe and efficient in the treatment of lesions located in the rectum. Method: Retrospective observational study with analysis of medical records of all patients undergoing resection of rectal polyps. Results: 123 patients with rectal lesions were evaluated, 59 men and 64 women and the mean age was 56 years. All were submitted to endoscopic resection, with polypectomy in 70% and wide mucosectomy in 30%. Complete colonoscopy with removal of the entire rectal lesion occurred in 91%, and in 5% the preparation was inadequate, and precarious clinical conditions were impeditive factors, and in 4% surgical treatment was indicated because it was an infiltrative lesion with central ulceration. The histological evaluation showed adenomas in 3.25%, hyperplastic in 7.32% and hamartoma in 0.81%, low-grade dysplasia was identified in 34.96%, and high-grade dysplasia in 51.22%, adenocarcinoma in 1.63% and 0.81% being one of the cases classified as erosion. Conclusion: Polyps in the rectum are common, occurring in 37% of colonoscopies. Adenomas with dysplasia were the most common. Therapeutic colonoscopy proved to be a safe and efficient method for the complete treatment of rectal lesions
id SCI-1_8ce5aeeb12e7ef424b0c50a004907e8f
oai_identifier_str oai:ops.preprints.scielo.org:preprint/4130
network_acronym_str SCI-1
network_name_str SciELO Preprints
repository_id_str
spelling MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONSANÁLISE MACROSCÓPICA E HISTOLÓGICA DE LESÕES RETAIS RESSECADAS ENDOSCOPICAMENTECâncer colorretalAdenomaMucosectomiaDisplasiaPólipoColorectal cancerAdenomaMucosectomyDysplasiaPolypBackground: Colorectal cancer (CRC) is among the most common malignancies worldwide. Colonoscopy is the exam of choice for the prevention of CRC due to its great diagnostic and mainly therapeutic capacity in the face of adenomatous lesions. Objective: To analyze the prevalence and the macroscopic and histological characteristics 2 of polypoid rectal lesions resected with endoscopic techniques and to assess whether endoscopic therapy is safe and efficient in the treatment of lesions located in the rectum. Method: Retrospective observational study with analysis of medical records of all patients undergoing resection of rectal polyps. Results: 123 patients with rectal lesions were evaluated, 59 men and 64 women and the mean age was 56 years. All were submitted to endoscopic resection, with polypectomy in 70% and wide mucosectomy in 30%. Complete colonoscopy with removal of the entire rectal lesion occurred in 91%, and in 5% the preparation was inadequate, and precarious clinical conditions were impeditive factors, and in 4% surgical treatment was indicated because it was an infiltrative lesion with central ulceration. The histological evaluation showed adenomas in 3.25%, hyperplastic in 7.32% and hamartoma in 0.81%, low-grade dysplasia was identified in 34.96%, and high-grade dysplasia in 51.22%, adenocarcinoma in 1.63% and 0.81% being one of the cases classified as erosion. Conclusion: Polyps in the rectum are common, occurring in 37% of colonoscopies. Adenomas with dysplasia were the most common. Therapeutic colonoscopy proved to be a safe and efficient method for the complete treatment of rectal lesionsRacional: O câncer colorretal (CCR) está entre as neoplasias malignas mais comuns em todo mundo. A colonoscopia é o exame de escolha para a prevenção do CCR devido sua grande capacidade diagnóstica e principalmente terapêutica frente às lesões adenomatosas. Objetivo: Analisar a prevalência e as características macroscópicas e histológicas de lesões polipoides retais, ressecadas com técnicas endoscópicas e avaliar se a terapêutica endoscópica é segura e eficiente no tratamento de lesões localizadas no reto. Método: Estudo retrospectivo observacional com análise de prontuário de todos pacientes submetidos a ressecção de pólipos retais. Resultados: Foram avaliados 123 portadores de lesões retais, sendo 59 homens e 64 mulheres e a faixa etária média foi 56 anos. Todos foram submetidos à ressecção endoscópica, sendo que em 70% realizou-se polipectomia e em 30% mucosectomia ampla. Colonoscopia completa com retirada de toda lesão retal ocorreu em 91%, sendo que em 5% o preparo foi inadequado, e condições clínicas precárias foram fatores impeditivos, e em 4% indicou-se tratamento cirúrgico por ser lesão infiltrativa e com ulceração central. A avaliação histológica evidenciou adenomas em 3,25%, hiperplásicos em 7,32% e hamartoma em 0,81%, displasia de baixo grau foi identificado em 34,96%, e displasia de alto grau em 51,22%, adenocarcinoma em 1,63% e 0,81% sendo um dos casos classificado como erosão. Conclusão: Pólipos no reto são comuns, ocorrendo em 37% das colonoscopias. Os adenomas com displasia foram os mais comuns. A colonoscopia terapêutica se mostrou método seguro e eficiente para o tratamento completo das lesões retaisSciELO PreprintsSciELO PreprintsSciELO Preprints2022-05-16info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/413010.1590/SciELOPreprints.4130porhttps://preprints.scielo.org/index.php/scielo/article/view/4130/7809Copyright (c) 2022 Marcos Onofre Frugis, Carmen Australia Paredes Marcondes Ribas, Osvaldo Malafaiahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFrugis, Marcos OnofreRibas, Carmen Australia Paredes MarcondesMalafaia, Osvaldoreponame:SciELO Preprintsinstname:SciELOinstacron:SCI2022-05-16T16:11:30Zoai:ops.preprints.scielo.org:preprint/4130Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2022-05-16T16:11:30SciELO Preprints - SciELOfalse
dc.title.none.fl_str_mv MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
ANÁLISE MACROSCÓPICA E HISTOLÓGICA DE LESÕES RETAIS RESSECADAS ENDOSCOPICAMENTE
title MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
spellingShingle MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
Frugis, Marcos Onofre
Câncer colorretal
Adenoma
Mucosectomia
Displasia
Pólipo
Colorectal cancer
Adenoma
Mucosectomy
Dysplasia
Polyp
title_short MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
title_full MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
title_fullStr MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
title_full_unstemmed MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
title_sort MACROSCOPIC AND HISTOLOGICAL ANALYSIS OF ENDOSCOPICALLY RESECTED RECTAL LESIONS
author Frugis, Marcos Onofre
author_facet Frugis, Marcos Onofre
Ribas, Carmen Australia Paredes Marcondes
Malafaia, Osvaldo
author_role author
author2 Ribas, Carmen Australia Paredes Marcondes
Malafaia, Osvaldo
author2_role author
author
dc.contributor.author.fl_str_mv Frugis, Marcos Onofre
Ribas, Carmen Australia Paredes Marcondes
Malafaia, Osvaldo
dc.subject.por.fl_str_mv Câncer colorretal
Adenoma
Mucosectomia
Displasia
Pólipo
Colorectal cancer
Adenoma
Mucosectomy
Dysplasia
Polyp
topic Câncer colorretal
Adenoma
Mucosectomia
Displasia
Pólipo
Colorectal cancer
Adenoma
Mucosectomy
Dysplasia
Polyp
description Background: Colorectal cancer (CRC) is among the most common malignancies worldwide. Colonoscopy is the exam of choice for the prevention of CRC due to its great diagnostic and mainly therapeutic capacity in the face of adenomatous lesions. Objective: To analyze the prevalence and the macroscopic and histological characteristics 2 of polypoid rectal lesions resected with endoscopic techniques and to assess whether endoscopic therapy is safe and efficient in the treatment of lesions located in the rectum. Method: Retrospective observational study with analysis of medical records of all patients undergoing resection of rectal polyps. Results: 123 patients with rectal lesions were evaluated, 59 men and 64 women and the mean age was 56 years. All were submitted to endoscopic resection, with polypectomy in 70% and wide mucosectomy in 30%. Complete colonoscopy with removal of the entire rectal lesion occurred in 91%, and in 5% the preparation was inadequate, and precarious clinical conditions were impeditive factors, and in 4% surgical treatment was indicated because it was an infiltrative lesion with central ulceration. The histological evaluation showed adenomas in 3.25%, hyperplastic in 7.32% and hamartoma in 0.81%, low-grade dysplasia was identified in 34.96%, and high-grade dysplasia in 51.22%, adenocarcinoma in 1.63% and 0.81% being one of the cases classified as erosion. Conclusion: Polyps in the rectum are common, occurring in 37% of colonoscopies. Adenomas with dysplasia were the most common. Therapeutic colonoscopy proved to be a safe and efficient method for the complete treatment of rectal lesions
publishDate 2022
dc.date.none.fl_str_mv 2022-05-16
dc.type.driver.fl_str_mv info:eu-repo/semantics/preprint
info:eu-repo/semantics/publishedVersion
format preprint
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://preprints.scielo.org/index.php/scielo/preprint/view/4130
10.1590/SciELOPreprints.4130
url https://preprints.scielo.org/index.php/scielo/preprint/view/4130
identifier_str_mv 10.1590/SciELOPreprints.4130
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://preprints.scielo.org/index.php/scielo/article/view/4130/7809
dc.rights.driver.fl_str_mv Copyright (c) 2022 Marcos Onofre Frugis, Carmen Australia Paredes Marcondes Ribas, Osvaldo Malafaia
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Marcos Onofre Frugis, Carmen Australia Paredes Marcondes Ribas, Osvaldo Malafaia
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
dc.source.none.fl_str_mv reponame:SciELO Preprints
instname:SciELO
instacron:SCI
instname_str SciELO
instacron_str SCI
institution SCI
reponame_str SciELO Preprints
collection SciELO Preprints
repository.name.fl_str_mv SciELO Preprints - SciELO
repository.mail.fl_str_mv scielo.submission@scielo.org
_version_ 1797047828513554432