Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina

Detalhes bibliográficos
Autor(a) principal: Vasconcelos, Giovani L.
Data de Publicação: 2020
Outros Autores: Duarte-Filho, Gerson C., Brum, Arthur A., Ospina, Raydonal, Almeida, Francisco A. G., Macêdo, Antônio M. S.
Tipo de documento: preprint
Idioma: por
Título da fonte: SciELO Preprints
Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/690
Resumo: Introduction: The Covid-19 pandemic is one of the biggest public health crises the world has ever faced. In this context, it is important to have effective models to describe the different stages of the epidemic’s evolution in order to guide the authorities in taking appropriate measures to fight the disease. Objective: To present an analysis of epidemic curves of Covid-19 based on phenomenological growth models, with applications to the curves for the cumulative numbers of confirmed cases of infection by the novel coronavirus (Sars-Cov-2) and deaths attributed to the disease (Covid-19) caused by the virus, for the Brazilian cities of Recife and Teresina. Methods: The Richards generalized model and the generalized growth model were used to make the numerical fits of the respective empirical curves. Results: The models used described very well the empirical curves against which they were tested. In particular, the generalized Richards model was able to identify the appearance of the inflexion point in the cumulative curves, which in turn represents the peak of the respective daily curves. A brief discussion is also presented on the relationship between the fitting parameters obtained from the model and the mitigation measures adopted in each of the municipalities considered. Conclusions: The generalized Richards model proved to be very effective in describing epidemic curves of Covid-19 and estimating important epidemiological parameters, such as the time of the peak of the curve for daily cases and deaths, thus allowing a practical and efficient monitoring of the epidemic evolution.
id SCI-1_d1eead52e9052815f28c4031b6599e52
oai_identifier_str oai:ops.preprints.scielo.org:preprint/690
network_acronym_str SCI-1
network_name_str SciELO Preprints
repository_id_str
spelling Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and TeresinaAnálise de curvas epidêmicas da Covid-19 via modelos generalizados de crescimento: Estudo de caso para as cidades de Recife e TeresinaCovid-19Modelos epidemiológicosPolíticas de saúde públicaModelos de crescimentoCOVID-19Epidemiological modelsGrowth modelPublic health policiesIntroduction: The Covid-19 pandemic is one of the biggest public health crises the world has ever faced. In this context, it is important to have effective models to describe the different stages of the epidemic’s evolution in order to guide the authorities in taking appropriate measures to fight the disease. Objective: To present an analysis of epidemic curves of Covid-19 based on phenomenological growth models, with applications to the curves for the cumulative numbers of confirmed cases of infection by the novel coronavirus (Sars-Cov-2) and deaths attributed to the disease (Covid-19) caused by the virus, for the Brazilian cities of Recife and Teresina. Methods: The Richards generalized model and the generalized growth model were used to make the numerical fits of the respective empirical curves. Results: The models used described very well the empirical curves against which they were tested. In particular, the generalized Richards model was able to identify the appearance of the inflexion point in the cumulative curves, which in turn represents the peak of the respective daily curves. A brief discussion is also presented on the relationship between the fitting parameters obtained from the model and the mitigation measures adopted in each of the municipalities considered. Conclusions: The generalized Richards model proved to be very effective in describing epidemic curves of Covid-19 and estimating important epidemiological parameters, such as the time of the peak of the curve for daily cases and deaths, thus allowing a practical and efficient monitoring of the epidemic evolution.Introdução: A pandemia da Covid-19 é uma das maiores crises de saúde pública que o mundo já enfrentou. Nesse contexto, é importante ter modelos eficazes para descrever os diferentes estágios da evolução da epidemia, a fim de orientar as autoridades competen- tes na adoção de políticas públicas para o enfrentamento da mesma. Objetivo: Apresentar uma análise de curvas epidêmicas com base em modelos fenomenológicos de crescimento, tomando como exemplo as curvas acumuladas de casos confirmados de infecção pelo novo coronavírus (Sars-Cov-2) e de óbitos atribuídos à doença (Covid-19) causada pelo vírus, para as cidades do Recife e Teresina. Métodos: Foram utilizados o modelo generalizado de Richards e o modelo de crescimento generalizado para fazer o ajuste numérico das respectivas curvas empíricas. Resultados: Verificou-se que os modelos utilizados descrevem muito bem as curvas empíricas em que foram testados. Em particular, o modelo generalizado de Richards é capaz de identificar com razoável confiabilidade o surgimento do ponto de infle- xão nas curvas acumuladas, o qual corresponde ao ponto de máximo das respectivas curvas diárias. Apresenta-se ainda uma breve discussão sobre a relação entre os parâmetros obtidos no ajuste do modelo e as medidas de mitigação adotadas para retardar a propagação da Covid-19 em cada um dos municípios considerados. Conclusões: O modelo generalizado de Richards mostrou-se bastante eficaz para descrever curvas epidêmicas da Covid-19 e es- timar parâmetros epidemiológicos importantes, como o pico das curvas de casos e óbitos diários, permitindo assim realizar de modo prático e eficiente o monitoramento da evolução da epidemia.SciELO PreprintsSciELO PreprintsSciELO Preprints2020-06-03info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/69010.1590/SciELOPreprints.690porhttps://preprints.scielo.org/index.php/scielo/article/view/690/905Copyright (c) 2020 Giovani L. Vasconcelos, Gerson C. Duarte-Filho, Arthur A. Brum, Raydonal Ospina, Francisco A. G. Almeida, Antônio M. S. Macêdohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessVasconcelos, Giovani L.Duarte-Filho, Gerson C. Brum, Arthur A. Ospina, RaydonalAlmeida, Francisco A. G. Macêdo, Antônio M. S. reponame:SciELO Preprintsinstname:SciELOinstacron:SCI2020-06-02T03:37:56Zoai:ops.preprints.scielo.org:preprint/690Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2020-06-02T03:37:56SciELO Preprints - SciELOfalse
dc.title.none.fl_str_mv Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
Análise de curvas epidêmicas da Covid-19 via modelos generalizados de crescimento: Estudo de caso para as cidades de Recife e Teresina
title Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
spellingShingle Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
Vasconcelos, Giovani L.
Covid-19
Modelos epidemiológicos
Políticas de saúde pública
Modelos de crescimento
COVID-19
Epidemiological models
Growth model
Public health policies
title_short Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
title_full Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
title_fullStr Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
title_full_unstemmed Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
title_sort Analysis of Covid-19 epidemic curves via generalized growth models: Case study for the cities of Recife and Teresina
author Vasconcelos, Giovani L.
author_facet Vasconcelos, Giovani L.
Duarte-Filho, Gerson C.
Brum, Arthur A.
Ospina, Raydonal
Almeida, Francisco A. G.
Macêdo, Antônio M. S.
author_role author
author2 Duarte-Filho, Gerson C.
Brum, Arthur A.
Ospina, Raydonal
Almeida, Francisco A. G.
Macêdo, Antônio M. S.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Vasconcelos, Giovani L.
Duarte-Filho, Gerson C.
Brum, Arthur A.
Ospina, Raydonal
Almeida, Francisco A. G.
Macêdo, Antônio M. S.
dc.subject.por.fl_str_mv Covid-19
Modelos epidemiológicos
Políticas de saúde pública
Modelos de crescimento
COVID-19
Epidemiological models
Growth model
Public health policies
topic Covid-19
Modelos epidemiológicos
Políticas de saúde pública
Modelos de crescimento
COVID-19
Epidemiological models
Growth model
Public health policies
description Introduction: The Covid-19 pandemic is one of the biggest public health crises the world has ever faced. In this context, it is important to have effective models to describe the different stages of the epidemic’s evolution in order to guide the authorities in taking appropriate measures to fight the disease. Objective: To present an analysis of epidemic curves of Covid-19 based on phenomenological growth models, with applications to the curves for the cumulative numbers of confirmed cases of infection by the novel coronavirus (Sars-Cov-2) and deaths attributed to the disease (Covid-19) caused by the virus, for the Brazilian cities of Recife and Teresina. Methods: The Richards generalized model and the generalized growth model were used to make the numerical fits of the respective empirical curves. Results: The models used described very well the empirical curves against which they were tested. In particular, the generalized Richards model was able to identify the appearance of the inflexion point in the cumulative curves, which in turn represents the peak of the respective daily curves. A brief discussion is also presented on the relationship between the fitting parameters obtained from the model and the mitigation measures adopted in each of the municipalities considered. Conclusions: The generalized Richards model proved to be very effective in describing epidemic curves of Covid-19 and estimating important epidemiological parameters, such as the time of the peak of the curve for daily cases and deaths, thus allowing a practical and efficient monitoring of the epidemic evolution.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/preprint
info:eu-repo/semantics/publishedVersion
format preprint
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://preprints.scielo.org/index.php/scielo/preprint/view/690
10.1590/SciELOPreprints.690
url https://preprints.scielo.org/index.php/scielo/preprint/view/690
identifier_str_mv 10.1590/SciELOPreprints.690
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://preprints.scielo.org/index.php/scielo/article/view/690/905
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
dc.source.none.fl_str_mv reponame:SciELO Preprints
instname:SciELO
instacron:SCI
instname_str SciELO
instacron_str SCI
institution SCI
reponame_str SciELO Preprints
collection SciELO Preprints
repository.name.fl_str_mv SciELO Preprints - SciELO
repository.mail.fl_str_mv scielo.submission@scielo.org
_version_ 1797047818500702208