FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020

Detalhes bibliográficos
Autor(a) principal: Candelo, Lilia Ruth Montaño
Data de Publicação: 2024
Outros Autores: Ardila, Janier Eduardo Miranda, Ceron, Lizeth Daniela Volverás, Oliveros, Simon Andres Giraldo
Tipo de documento: preprint
Idioma: spa
Título da fonte: SciELO Preprints
Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/8326
Resumo: Introduction: Chronic Kidney Disease (CKD) involves a progressive deterioration in kidney function, affecting the ability to filter metabolic waste. Factors such as age, family history, ethnicity, sex, and unhealthy habits may contribute to progression to stage 5 (CKD-5). Methodology: Retrospective observational study analyzed patients with hypertension, diabetes, morbid obesity, dyslipidemia and CKD in Valle del Cauca from 2018 to 2020. Cases with CKD-5, previous dialysis, and significant changes were excluded. A census was used as a sampling method, consolidating quarterly data in 12 databases. The analysis addressed sociodemographic and clinical factors, evaluating associations with binary logistic regression, and the study was ethically approved. Results: In a cohort of 57,643 patients with CKD stages 1 to 4, the majority began follow-up in stages 2 and 3. The prevalent comorbidities were hypertension, overweight and obesity. The incidence of CKD-5 was 6 new cases per 1000 patients, being higher in the population aged 30 to 44 years, male, non-ethnic, not belonging to vulnerable groups and residing in certain municipalities. Factors such as uncontrolled blood pressure, lack of specific medication and follow-up in advanced renal stages were significantly associated with the incidence of CKD stage 5. In addition, a direct relationship was observed between the advancement of renal stage and the increase in creatinine in the blood, albumin in urine, total cholesterol and HDL cholesterol. Patients who advanced to stage 5 showed significantly higher levels of blood creatinine, albuminuria, total cholesterol, and LDL cholesterol compared to those who remained in stage 4 or lower.
id SCI-1_d770fd7ca2b70c0551f42defce6bce4d
oai_identifier_str oai:ops.preprints.scielo.org:preprint/8326
network_acronym_str SCI-1
network_name_str SciELO Preprints
repository_id_str
spelling FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020FACTORES ASOCIADOS A LA ERC-5 EN PACIENTES DE UNA EPS DEL VALLE DEL CAUCA 2018-2020Insuficiencia Renal CrónicaDiabetes mellitusHipertensiónFallo Renal CrónicoDiálisisFactores de RiesgoChronic Renal DiseaseHypertensionDiabetes MellitusKidney FailureChronicDialysisRisk FactorsIntroduction: Chronic Kidney Disease (CKD) involves a progressive deterioration in kidney function, affecting the ability to filter metabolic waste. Factors such as age, family history, ethnicity, sex, and unhealthy habits may contribute to progression to stage 5 (CKD-5). Methodology: Retrospective observational study analyzed patients with hypertension, diabetes, morbid obesity, dyslipidemia and CKD in Valle del Cauca from 2018 to 2020. Cases with CKD-5, previous dialysis, and significant changes were excluded. A census was used as a sampling method, consolidating quarterly data in 12 databases. The analysis addressed sociodemographic and clinical factors, evaluating associations with binary logistic regression, and the study was ethically approved. Results: In a cohort of 57,643 patients with CKD stages 1 to 4, the majority began follow-up in stages 2 and 3. The prevalent comorbidities were hypertension, overweight and obesity. The incidence of CKD-5 was 6 new cases per 1000 patients, being higher in the population aged 30 to 44 years, male, non-ethnic, not belonging to vulnerable groups and residing in certain municipalities. Factors such as uncontrolled blood pressure, lack of specific medication and follow-up in advanced renal stages were significantly associated with the incidence of CKD stage 5. In addition, a direct relationship was observed between the advancement of renal stage and the increase in creatinine in the blood, albumin in urine, total cholesterol and HDL cholesterol. Patients who advanced to stage 5 showed significantly higher levels of blood creatinine, albuminuria, total cholesterol, and LDL cholesterol compared to those who remained in stage 4 or lower.Introducción: La Enfermedad Renal Crónica (ERC) implica un deterioro progresivo en la función renal, afectando la capacidad de filtrar desechos metabólicos. Factores como edad, antecedentes familiares, etnia, sexo, y hábitos poco saludables pueden contribuir a la progresión hacia el estadio 5 (ERC-5). Metodología: Estudio observacional retrospectivo analizó pacientes con hipertensión, diabetes, obesidad mórbida, dislipidemia y ERC en el Valle del Cauca de 2018 a 2020. Se excluyeron casos con ERC-5, diálisis previa, y cambios significativos. Se utilizó un censo como método de muestreo, consolidando datos trimestrales en 12 bases. El análisis abordó factores sociodemográficos y clínicos, evaluando asociaciones con regresión logística binaria, y el estudio fue éticamente aprobado. Resultados: En una cohorte de 57,643 pacientes con ERC estadios 1 a 4, la mayoría inició el seguimiento en estadios 2 y 3. Las comorbilidades prevalentes fueron hipertensión, sobrepeso y obesidad. La incidencia de ERC-5 fue de 6 casos nuevos por cada 1000 pacientes, siendo mayor en población de 30 a 44 años, sexo masculino, no étnica, no perteneciente a grupos vulnerables y residente en ciertos municipios. Factores como la presión arterial no controlada, falta de medicación específica y seguimiento en estadios renales avanzados se asociaron significativamente con la incidencia de ERC estadio 5. Además, se observó una relación directa entre el avance de estadio renal y el incremento de creatinina en sangre, albumina en orina, colesterol total y colesterol HDL. Los pacientes que avanzaron a estadio 5 mostraron niveles significativamente superiores de creatinina en sangre, albuminuria, colesterol total y colesterol LDL en comparación con los que permanecieron en fase 4 o inferior.SciELO PreprintsSciELO PreprintsSciELO Preprints2024-04-22info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/832610.1590/SciELOPreprints.8326spahttps://preprints.scielo.org/index.php/scielo/article/view/8326/15706Copyright (c) 2024 Lilia Ruth Montaño Candelo, Janier Eduardo Miranda Ardila, Lizeth Daniela Volverás Ceron, Simon Andres Giraldo Oliveroshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCandelo, Lilia Ruth MontañoArdila, Janier Eduardo MirandaCeron, Lizeth Daniela VolverásOliveros, Simon Andres Giraldoreponame:SciELO Preprintsinstname:Scientific Electronic Library Online (SCIELO)instacron:SCI2024-04-06T18:36:55Zoai:ops.preprints.scielo.org:preprint/8326Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2024-04-06T18:36:55SciELO Preprints - Scientific Electronic Library Online (SCIELO)false
dc.title.none.fl_str_mv FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
FACTORES ASOCIADOS A LA ERC-5 EN PACIENTES DE UNA EPS DEL VALLE DEL CAUCA 2018-2020
title FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
spellingShingle FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
Candelo, Lilia Ruth Montaño
Insuficiencia Renal Crónica
Diabetes mellitus
Hipertensión
Fallo Renal Crónico
Diálisis
Factores de Riesgo
Chronic Renal Disease
Hypertension
Diabetes Mellitus
Kidney Failure
Chronic
Dialysis
Risk Factors
title_short FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
title_full FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
title_fullStr FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
title_full_unstemmed FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
title_sort FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
author Candelo, Lilia Ruth Montaño
author_facet Candelo, Lilia Ruth Montaño
Ardila, Janier Eduardo Miranda
Ceron, Lizeth Daniela Volverás
Oliveros, Simon Andres Giraldo
author_role author
author2 Ardila, Janier Eduardo Miranda
Ceron, Lizeth Daniela Volverás
Oliveros, Simon Andres Giraldo
author2_role author
author
author
dc.contributor.author.fl_str_mv Candelo, Lilia Ruth Montaño
Ardila, Janier Eduardo Miranda
Ceron, Lizeth Daniela Volverás
Oliveros, Simon Andres Giraldo
dc.subject.por.fl_str_mv Insuficiencia Renal Crónica
Diabetes mellitus
Hipertensión
Fallo Renal Crónico
Diálisis
Factores de Riesgo
Chronic Renal Disease
Hypertension
Diabetes Mellitus
Kidney Failure
Chronic
Dialysis
Risk Factors
topic Insuficiencia Renal Crónica
Diabetes mellitus
Hipertensión
Fallo Renal Crónico
Diálisis
Factores de Riesgo
Chronic Renal Disease
Hypertension
Diabetes Mellitus
Kidney Failure
Chronic
Dialysis
Risk Factors
description Introduction: Chronic Kidney Disease (CKD) involves a progressive deterioration in kidney function, affecting the ability to filter metabolic waste. Factors such as age, family history, ethnicity, sex, and unhealthy habits may contribute to progression to stage 5 (CKD-5). Methodology: Retrospective observational study analyzed patients with hypertension, diabetes, morbid obesity, dyslipidemia and CKD in Valle del Cauca from 2018 to 2020. Cases with CKD-5, previous dialysis, and significant changes were excluded. A census was used as a sampling method, consolidating quarterly data in 12 databases. The analysis addressed sociodemographic and clinical factors, evaluating associations with binary logistic regression, and the study was ethically approved. Results: In a cohort of 57,643 patients with CKD stages 1 to 4, the majority began follow-up in stages 2 and 3. The prevalent comorbidities were hypertension, overweight and obesity. The incidence of CKD-5 was 6 new cases per 1000 patients, being higher in the population aged 30 to 44 years, male, non-ethnic, not belonging to vulnerable groups and residing in certain municipalities. Factors such as uncontrolled blood pressure, lack of specific medication and follow-up in advanced renal stages were significantly associated with the incidence of CKD stage 5. In addition, a direct relationship was observed between the advancement of renal stage and the increase in creatinine in the blood, albumin in urine, total cholesterol and HDL cholesterol. Patients who advanced to stage 5 showed significantly higher levels of blood creatinine, albuminuria, total cholesterol, and LDL cholesterol compared to those who remained in stage 4 or lower.
publishDate 2024
dc.date.none.fl_str_mv 2024-04-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/preprint
info:eu-repo/semantics/publishedVersion
format preprint
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://preprints.scielo.org/index.php/scielo/preprint/view/8326
10.1590/SciELOPreprints.8326
url https://preprints.scielo.org/index.php/scielo/preprint/view/8326
identifier_str_mv 10.1590/SciELOPreprints.8326
dc.language.iso.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://preprints.scielo.org/index.php/scielo/article/view/8326/15706
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
publisher.none.fl_str_mv SciELO Preprints
SciELO Preprints
SciELO Preprints
dc.source.none.fl_str_mv reponame:SciELO Preprints
instname:Scientific Electronic Library Online (SCIELO)
instacron:SCI
instname_str Scientific Electronic Library Online (SCIELO)
instacron_str SCI
institution SCI
reponame_str SciELO Preprints
collection SciELO Preprints
repository.name.fl_str_mv SciELO Preprints - Scientific Electronic Library Online (SCIELO)
repository.mail.fl_str_mv scielo.submission@scielo.org
_version_ 1797047815382237184