FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020
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Data de Publicação: | 2024 |
Outros Autores: | , , |
Tipo de documento: | preprint |
Idioma: | spa |
Título da fonte: | SciELO Preprints |
Texto Completo: | https://preprints.scielo.org/index.php/scielo/preprint/view/8326 |
Resumo: | Introduction: Chronic Kidney Disease (CKD) involves a progressive deterioration in kidney function, affecting the ability to filter metabolic waste. Factors such as age, family history, ethnicity, sex, and unhealthy habits may contribute to progression to stage 5 (CKD-5). Methodology: Retrospective observational study analyzed patients with hypertension, diabetes, morbid obesity, dyslipidemia and CKD in Valle del Cauca from 2018 to 2020. Cases with CKD-5, previous dialysis, and significant changes were excluded. A census was used as a sampling method, consolidating quarterly data in 12 databases. The analysis addressed sociodemographic and clinical factors, evaluating associations with binary logistic regression, and the study was ethically approved. Results: In a cohort of 57,643 patients with CKD stages 1 to 4, the majority began follow-up in stages 2 and 3. The prevalent comorbidities were hypertension, overweight and obesity. The incidence of CKD-5 was 6 new cases per 1000 patients, being higher in the population aged 30 to 44 years, male, non-ethnic, not belonging to vulnerable groups and residing in certain municipalities. Factors such as uncontrolled blood pressure, lack of specific medication and follow-up in advanced renal stages were significantly associated with the incidence of CKD stage 5. In addition, a direct relationship was observed between the advancement of renal stage and the increase in creatinine in the blood, albumin in urine, total cholesterol and HDL cholesterol. Patients who advanced to stage 5 showed significantly higher levels of blood creatinine, albuminuria, total cholesterol, and LDL cholesterol compared to those who remained in stage 4 or lower. |
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FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020FACTORES ASOCIADOS A LA ERC-5 EN PACIENTES DE UNA EPS DEL VALLE DEL CAUCA 2018-2020Insuficiencia Renal CrónicaDiabetes mellitusHipertensiónFallo Renal CrónicoDiálisisFactores de RiesgoChronic Renal DiseaseHypertensionDiabetes MellitusKidney FailureChronicDialysisRisk FactorsIntroduction: Chronic Kidney Disease (CKD) involves a progressive deterioration in kidney function, affecting the ability to filter metabolic waste. Factors such as age, family history, ethnicity, sex, and unhealthy habits may contribute to progression to stage 5 (CKD-5). Methodology: Retrospective observational study analyzed patients with hypertension, diabetes, morbid obesity, dyslipidemia and CKD in Valle del Cauca from 2018 to 2020. Cases with CKD-5, previous dialysis, and significant changes were excluded. A census was used as a sampling method, consolidating quarterly data in 12 databases. The analysis addressed sociodemographic and clinical factors, evaluating associations with binary logistic regression, and the study was ethically approved. Results: In a cohort of 57,643 patients with CKD stages 1 to 4, the majority began follow-up in stages 2 and 3. The prevalent comorbidities were hypertension, overweight and obesity. The incidence of CKD-5 was 6 new cases per 1000 patients, being higher in the population aged 30 to 44 years, male, non-ethnic, not belonging to vulnerable groups and residing in certain municipalities. Factors such as uncontrolled blood pressure, lack of specific medication and follow-up in advanced renal stages were significantly associated with the incidence of CKD stage 5. In addition, a direct relationship was observed between the advancement of renal stage and the increase in creatinine in the blood, albumin in urine, total cholesterol and HDL cholesterol. Patients who advanced to stage 5 showed significantly higher levels of blood creatinine, albuminuria, total cholesterol, and LDL cholesterol compared to those who remained in stage 4 or lower.Introducción: La Enfermedad Renal Crónica (ERC) implica un deterioro progresivo en la función renal, afectando la capacidad de filtrar desechos metabólicos. Factores como edad, antecedentes familiares, etnia, sexo, y hábitos poco saludables pueden contribuir a la progresión hacia el estadio 5 (ERC-5). Metodología: Estudio observacional retrospectivo analizó pacientes con hipertensión, diabetes, obesidad mórbida, dislipidemia y ERC en el Valle del Cauca de 2018 a 2020. Se excluyeron casos con ERC-5, diálisis previa, y cambios significativos. Se utilizó un censo como método de muestreo, consolidando datos trimestrales en 12 bases. El análisis abordó factores sociodemográficos y clínicos, evaluando asociaciones con regresión logística binaria, y el estudio fue éticamente aprobado. Resultados: En una cohorte de 57,643 pacientes con ERC estadios 1 a 4, la mayoría inició el seguimiento en estadios 2 y 3. Las comorbilidades prevalentes fueron hipertensión, sobrepeso y obesidad. La incidencia de ERC-5 fue de 6 casos nuevos por cada 1000 pacientes, siendo mayor en población de 30 a 44 años, sexo masculino, no étnica, no perteneciente a grupos vulnerables y residente en ciertos municipios. Factores como la presión arterial no controlada, falta de medicación específica y seguimiento en estadios renales avanzados se asociaron significativamente con la incidencia de ERC estadio 5. Además, se observó una relación directa entre el avance de estadio renal y el incremento de creatinina en sangre, albumina en orina, colesterol total y colesterol HDL. Los pacientes que avanzaron a estadio 5 mostraron niveles significativamente superiores de creatinina en sangre, albuminuria, colesterol total y colesterol LDL en comparación con los que permanecieron en fase 4 o inferior.SciELO PreprintsSciELO PreprintsSciELO Preprints2024-04-22info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/832610.1590/SciELOPreprints.8326spahttps://preprints.scielo.org/index.php/scielo/article/view/8326/15706Copyright (c) 2024 Lilia Ruth Montaño Candelo, Janier Eduardo Miranda Ardila, Lizeth Daniela Volverás Ceron, Simon Andres Giraldo Oliveroshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCandelo, Lilia Ruth MontañoArdila, Janier Eduardo MirandaCeron, Lizeth Daniela VolverásOliveros, Simon Andres Giraldoreponame:SciELO Preprintsinstname:Scientific Electronic Library Online (SCIELO)instacron:SCI2024-04-06T18:36:55Zoai:ops.preprints.scielo.org:preprint/8326Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2024-04-06T18:36:55SciELO Preprints - Scientific Electronic Library Online (SCIELO)false |
dc.title.none.fl_str_mv |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 FACTORES ASOCIADOS A LA ERC-5 EN PACIENTES DE UNA EPS DEL VALLE DEL CAUCA 2018-2020 |
title |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 |
spellingShingle |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 Candelo, Lilia Ruth Montaño Insuficiencia Renal Crónica Diabetes mellitus Hipertensión Fallo Renal Crónico Diálisis Factores de Riesgo Chronic Renal Disease Hypertension Diabetes Mellitus Kidney Failure Chronic Dialysis Risk Factors |
title_short |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 |
title_full |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 |
title_fullStr |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 |
title_full_unstemmed |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 |
title_sort |
FACTORS ASSOCIATED WITH ERC-5 IN PATIENTS OF AN EPS IN VALLE DEL CAUCA 2018-2020 |
author |
Candelo, Lilia Ruth Montaño |
author_facet |
Candelo, Lilia Ruth Montaño Ardila, Janier Eduardo Miranda Ceron, Lizeth Daniela Volverás Oliveros, Simon Andres Giraldo |
author_role |
author |
author2 |
Ardila, Janier Eduardo Miranda Ceron, Lizeth Daniela Volverás Oliveros, Simon Andres Giraldo |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Candelo, Lilia Ruth Montaño Ardila, Janier Eduardo Miranda Ceron, Lizeth Daniela Volverás Oliveros, Simon Andres Giraldo |
dc.subject.por.fl_str_mv |
Insuficiencia Renal Crónica Diabetes mellitus Hipertensión Fallo Renal Crónico Diálisis Factores de Riesgo Chronic Renal Disease Hypertension Diabetes Mellitus Kidney Failure Chronic Dialysis Risk Factors |
topic |
Insuficiencia Renal Crónica Diabetes mellitus Hipertensión Fallo Renal Crónico Diálisis Factores de Riesgo Chronic Renal Disease Hypertension Diabetes Mellitus Kidney Failure Chronic Dialysis Risk Factors |
description |
Introduction: Chronic Kidney Disease (CKD) involves a progressive deterioration in kidney function, affecting the ability to filter metabolic waste. Factors such as age, family history, ethnicity, sex, and unhealthy habits may contribute to progression to stage 5 (CKD-5). Methodology: Retrospective observational study analyzed patients with hypertension, diabetes, morbid obesity, dyslipidemia and CKD in Valle del Cauca from 2018 to 2020. Cases with CKD-5, previous dialysis, and significant changes were excluded. A census was used as a sampling method, consolidating quarterly data in 12 databases. The analysis addressed sociodemographic and clinical factors, evaluating associations with binary logistic regression, and the study was ethically approved. Results: In a cohort of 57,643 patients with CKD stages 1 to 4, the majority began follow-up in stages 2 and 3. The prevalent comorbidities were hypertension, overweight and obesity. The incidence of CKD-5 was 6 new cases per 1000 patients, being higher in the population aged 30 to 44 years, male, non-ethnic, not belonging to vulnerable groups and residing in certain municipalities. Factors such as uncontrolled blood pressure, lack of specific medication and follow-up in advanced renal stages were significantly associated with the incidence of CKD stage 5. In addition, a direct relationship was observed between the advancement of renal stage and the increase in creatinine in the blood, albumin in urine, total cholesterol and HDL cholesterol. Patients who advanced to stage 5 showed significantly higher levels of blood creatinine, albuminuria, total cholesterol, and LDL cholesterol compared to those who remained in stage 4 or lower. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-04-22 |
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preprint |
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https://preprints.scielo.org/index.php/scielo/preprint/view/8326 10.1590/SciELOPreprints.8326 |
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https://preprints.scielo.org/index.php/scielo/preprint/view/8326 |
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10.1590/SciELOPreprints.8326 |
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https://preprints.scielo.org/index.php/scielo/article/view/8326/15706 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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