Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment

Detalhes bibliográficos
Autor(a) principal: Marinho, Pabliane Matias Lordelo
Data de Publicação: 2023
Outros Autores: Barbosa-Lima, Ricardo, Silva, Glebson Moura, Kameo, Simone Yuriko, Okino Sawada, Namie
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Enfermagem Atual In Derme
DOI: 10.31011/reaid-2023-v.97-n.3-art.1925
Texto Completo: https://revistaenfermagematual.com/index.php/revista/article/view/1925
Resumo: Introduction: Chemotherapy can cause adverse events in the oral cavity, such as mucosal lesions and changes in salivary flow. However, the association between these events has not been evaluated. Objective: To evaluate the association between oral mucositis and xerostomia during chemotherapy for the treatment of breast cancer. Methods: This was an observational and prospective study carried out with 140 women who underwent chemotherapy treatment for breast cancer in three cancer centers, evaluating them in two segments: in the intermediate cycle and at the end of treatment. Results: A high frequency of oral mucositis (87.5%) and xerostomia (82.9%) was observed after exposure to chemotherapy agents, but there was no significant association between both in the study segments (p >0.05 ). However, 60% simultaneously manifested oral mucositis and xerostomia in at least one segment, with a significant association of the double-hit being observed between the studied segments (p <0.001). Conclusion: Oral mucositis and xerostomia were not consistently associated in breast cancer patients during chemotherapy.
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spelling Association between oral mucositis and xerostomia during breast cancer chemotherapy treatmentAsociación entre mucositis oral y xerostomía durante el tratamiento quimioterápico del cáncer de mamaAssociação entre mucosite oral e xerostomia durante o tratamento quimioterápico do câncer de mamaSaúde BucalCâncer de MamaQuimioterapiaMucosite OralXerostomiaOral HealthBreast NeoplasmsChemotherapyOral MucositisXerostomiaSalud BucalNeoplasias de la MamaQuimioterapiaMucositis OralXerostomíaIntroduction: Chemotherapy can cause adverse events in the oral cavity, such as mucosal lesions and changes in salivary flow. However, the association between these events has not been evaluated. Objective: To evaluate the association between oral mucositis and xerostomia during chemotherapy for the treatment of breast cancer. Methods: This was an observational and prospective study carried out with 140 women who underwent chemotherapy treatment for breast cancer in three cancer centers, evaluating them in two segments: in the intermediate cycle and at the end of treatment. Results: A high frequency of oral mucositis (87.5%) and xerostomia (82.9%) was observed after exposure to chemotherapy agents, but there was no significant association between both in the study segments (p >0.05 ). However, 60% simultaneously manifested oral mucositis and xerostomia in at least one segment, with a significant association of the double-hit being observed between the studied segments (p <0.001). Conclusion: Oral mucositis and xerostomia were not consistently associated in breast cancer patients during chemotherapy.Introducción: La quimioterapia puede ocasionar eventos adversos en la cavidad bucal, como lesiones mucosas y cambios en el flujo salival. Sin embargo, la asociación entre tales eventos no ha sido evaluada. Objetivo: Evaluar la asociación entre mucositis oral y xerostomía durante la quimioterapia para el tratamiento del cáncer de mama. Métodos: Se trata de un estudio observacional y prospectivo realizado con 140 mujeres que se sometieron a tratamiento quimioterápico por cáncer de mama en tres centros oncológicos, evaluándolas en dos segmentos: en el ciclo intermedio y al final del tratamiento. Resultados: Se observó una alta frecuencia de mucositis oral (87,5%) y xerostomía (82,9%) después de la exposición a agentes quimioterápicos, pero no hubo asociación significativa entre ambas en los segmentos de estudio (p >0,05). Sin embargo, el 60% manifestó simultáneamente mucositis oral y xerostomía en al menos un segmento, observándose una asociación significativa de la doble ocurrencia entre los segmentos estudiados (p <0,001). Conclusión: La mucositis oral y la xerostomía no se asociaron consistentemente en pacientes con cáncer de mama durante la quimioterapia.Introdução: A quimioterapia pode provocar eventos adversos na cavidade bucal, como lesões na mucosa e alterações no fluxo salivar. Entretanto, a associação entre tais eventos não foi avaliada. Objetivo: Avaliar a associação entre mucosite oral e xerostomia durante a quimioterapia para o tratamento do câncer de mama. Métodos: Trata-se de um estudo observacional e prospectivo realizado com 140 mulheres que realizaram tratamento quimioterápico para o câncer de mama em três centros oncológicos, avaliando-as em dois segmentos: no ciclo intermediário e ao fim do tratamento. Resultados: Observou-se uma alta frequência de mucosite oral (87,5%) e xerostomia (82,9%) após a exposição aos agentes quimioterápicos, mas não houve uma associação significativa entre ambos nos segmentos do estudo (p >0,05). Entretanto, 60% manifestaram simultaneamente mucosite oral e xerostomia em pelo menos um segmento, sendo observada uma associação  significativa da dupla ocorrência entre os segmentos do estudado (p <0,001). Conclusão: Mucosite oral e xerostomia não estiveram consistentemente associadas em pacientes com câncer de mama durante a quimioterapia.SOBENFeE2023-08-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistaenfermagematual.com/index.php/revista/article/view/192510.31011/reaid-2023-v.97-n.3-art.1925Journal Enfermagem Atual In Derme; Vol. 97 No. 3 (2023): jul. ago. set.; e023142Revista Enfermagem Atual In Derme; v. 97 n. 3 (2023): jul. ago. set.; e0231422447-2034reponame:Revista Enfermagem Atual In Dermeinstname:Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE)instacron:SOBENFeEenghttps://revistaenfermagematual.com/index.php/revista/article/view/1925/1976https://revistaenfermagematual.com/index.php/revista/article/view/1925/1977Copyright (c) 2023 Revista Enfermagem Atual In Dermehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarinho, Pabliane Matias LordeloBarbosa-Lima, RicardoSilva, Glebson MouraKameo, Simone YurikoOkino Sawada, Namie2023-08-31T13:51:40Zoai:revistae_ojs.revistaenfermagematual.a2hosted.com:article/1925Revistahttps://revistaenfermagematual.com/index.php/revista/indexONGhttps://revistaenfermagematual.com/index.php/revista/oaikatia.simoes@gmail.com || contato@revistaenfermagematual.com.br2447-20342447-2034opendoar:2023-08-31T13:51:40Revista Enfermagem Atual In Derme - Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE)false
dc.title.none.fl_str_mv Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
Asociación entre mucositis oral y xerostomía durante el tratamiento quimioterápico del cáncer de mama
Associação entre mucosite oral e xerostomia durante o tratamento quimioterápico do câncer de mama
title Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
spellingShingle Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
Marinho, Pabliane Matias Lordelo
Saúde Bucal
Câncer de Mama
Quimioterapia
Mucosite Oral
Xerostomia
Oral Health
Breast Neoplasms
Chemotherapy
Oral Mucositis
Xerostomia
Salud Bucal
Neoplasias de la Mama
Quimioterapia
Mucositis Oral
Xerostomía
Marinho, Pabliane Matias Lordelo
Saúde Bucal
Câncer de Mama
Quimioterapia
Mucosite Oral
Xerostomia
Oral Health
Breast Neoplasms
Chemotherapy
Oral Mucositis
Xerostomia
Salud Bucal
Neoplasias de la Mama
Quimioterapia
Mucositis Oral
Xerostomía
title_short Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
title_full Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
title_fullStr Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
title_full_unstemmed Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
title_sort Association between oral mucositis and xerostomia during breast cancer chemotherapy treatment
author Marinho, Pabliane Matias Lordelo
author_facet Marinho, Pabliane Matias Lordelo
Marinho, Pabliane Matias Lordelo
Barbosa-Lima, Ricardo
Silva, Glebson Moura
Kameo, Simone Yuriko
Okino Sawada, Namie
Barbosa-Lima, Ricardo
Silva, Glebson Moura
Kameo, Simone Yuriko
Okino Sawada, Namie
author_role author
author2 Barbosa-Lima, Ricardo
Silva, Glebson Moura
Kameo, Simone Yuriko
Okino Sawada, Namie
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Marinho, Pabliane Matias Lordelo
Barbosa-Lima, Ricardo
Silva, Glebson Moura
Kameo, Simone Yuriko
Okino Sawada, Namie
dc.subject.por.fl_str_mv Saúde Bucal
Câncer de Mama
Quimioterapia
Mucosite Oral
Xerostomia
Oral Health
Breast Neoplasms
Chemotherapy
Oral Mucositis
Xerostomia
Salud Bucal
Neoplasias de la Mama
Quimioterapia
Mucositis Oral
Xerostomía
topic Saúde Bucal
Câncer de Mama
Quimioterapia
Mucosite Oral
Xerostomia
Oral Health
Breast Neoplasms
Chemotherapy
Oral Mucositis
Xerostomia
Salud Bucal
Neoplasias de la Mama
Quimioterapia
Mucositis Oral
Xerostomía
description Introduction: Chemotherapy can cause adverse events in the oral cavity, such as mucosal lesions and changes in salivary flow. However, the association between these events has not been evaluated. Objective: To evaluate the association between oral mucositis and xerostomia during chemotherapy for the treatment of breast cancer. Methods: This was an observational and prospective study carried out with 140 women who underwent chemotherapy treatment for breast cancer in three cancer centers, evaluating them in two segments: in the intermediate cycle and at the end of treatment. Results: A high frequency of oral mucositis (87.5%) and xerostomia (82.9%) was observed after exposure to chemotherapy agents, but there was no significant association between both in the study segments (p >0.05 ). However, 60% simultaneously manifested oral mucositis and xerostomia in at least one segment, with a significant association of the double-hit being observed between the studied segments (p <0.001). Conclusion: Oral mucositis and xerostomia were not consistently associated in breast cancer patients during chemotherapy.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-30
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dc.identifier.uri.fl_str_mv https://revistaenfermagematual.com/index.php/revista/article/view/1925
10.31011/reaid-2023-v.97-n.3-art.1925
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identifier_str_mv 10.31011/reaid-2023-v.97-n.3-art.1925
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaenfermagematual.com/index.php/revista/article/view/1925/1976
https://revistaenfermagematual.com/index.php/revista/article/view/1925/1977
dc.rights.driver.fl_str_mv Copyright (c) 2023 Revista Enfermagem Atual In Derme
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Revista Enfermagem Atual In Derme
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv SOBENFeE
publisher.none.fl_str_mv SOBENFeE
dc.source.none.fl_str_mv Journal Enfermagem Atual In Derme; Vol. 97 No. 3 (2023): jul. ago. set.; e023142
Revista Enfermagem Atual In Derme; v. 97 n. 3 (2023): jul. ago. set.; e023142
2447-2034
reponame:Revista Enfermagem Atual In Derme
instname:Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE)
instacron:SOBENFeE
instname_str Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE)
instacron_str SOBENFeE
institution SOBENFeE
reponame_str Revista Enfermagem Atual In Derme
collection Revista Enfermagem Atual In Derme
repository.name.fl_str_mv Revista Enfermagem Atual In Derme - Sociedade Brasileira de Enfermagem em Feridas e Estética (SOBENFeE)
repository.mail.fl_str_mv katia.simoes@gmail.com || contato@revistaenfermagematual.com.br
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dc.identifier.doi.none.fl_str_mv 10.31011/reaid-2023-v.97-n.3-art.1925

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