Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service

Detalhes bibliográficos
Autor(a) principal: Mourato,Felipe Alves
Data de Publicação: 2014
Outros Autores: Villachan,Lúcia Roberta R., Mattos,Sandra da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Paulista de Pediatria (Ed. Português. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822014000200159
Resumo: OBJECTIVE:To determine the frequence and profile of congenital heart defects in Down syndrome patients referred to a pediatric cardiologic center, considering the age of referral, gender, type of heart disease diagnosed by transthoracic echocardiography and its association with pulmonary hypertension at the initial diagnosis.METHODS:Cross-sectional study with retrospective data collection of 138 patients with Down syndrome from a total of 17,873 records. Descriptive analysis of the data was performed, using Epi-Info version 7.RESULTS: Among the 138 patients with Down syndrome, females prevailed (56.1%) and 112 (81.2%) were diagnosed with congenital heart disease. The most common lesion was ostium secundum atrial septal defect, present in 51.8%, followed by atrioventricular septal defect, in 46.4%. Ventricular septal defects were present in 27.7%, while tetralogy of Fallot represented 6.3% of the cases. Other cardiac malformations corresponded to 12.5%. Pulmonary hypertension was associated with 37.5% of the heart diseases. Only 35.5% of the patients were referred before six months of age.CONCLUSIONS: The low percentage of referral until six months of age highlights the need for a better tracking of patients with Down syndrome in the context of congenital heart disease, due to the high frequency and progression of pulmonary hypertension.
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spelling Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology servicehypertension, pulmonaryheart defects, congenitalDown syndromeOBJECTIVE:To determine the frequence and profile of congenital heart defects in Down syndrome patients referred to a pediatric cardiologic center, considering the age of referral, gender, type of heart disease diagnosed by transthoracic echocardiography and its association with pulmonary hypertension at the initial diagnosis.METHODS:Cross-sectional study with retrospective data collection of 138 patients with Down syndrome from a total of 17,873 records. Descriptive analysis of the data was performed, using Epi-Info version 7.RESULTS: Among the 138 patients with Down syndrome, females prevailed (56.1%) and 112 (81.2%) were diagnosed with congenital heart disease. The most common lesion was ostium secundum atrial septal defect, present in 51.8%, followed by atrioventricular septal defect, in 46.4%. Ventricular septal defects were present in 27.7%, while tetralogy of Fallot represented 6.3% of the cases. Other cardiac malformations corresponded to 12.5%. Pulmonary hypertension was associated with 37.5% of the heart diseases. Only 35.5% of the patients were referred before six months of age.CONCLUSIONS: The low percentage of referral until six months of age highlights the need for a better tracking of patients with Down syndrome in the context of congenital heart disease, due to the high frequency and progression of pulmonary hypertension.Sociedade de Pediatria de São Paulo2014-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822014000200159Revista Paulista de Pediatria v.32 n.2 2014reponame:Revista Paulista de Pediatria (Ed. Português. Online)instname:Sociedade de Pediatria de São Paulo (SPSP)instacron:SPSP10.1590/0103-0582201432218913info:eu-repo/semantics/openAccessMourato,Felipe AlvesVillachan,Lúcia Roberta R.Mattos,Sandra da Silvaeng2015-09-01T00:00:00Zoai:scielo:S0103-05822014000200159Revistahttps://www.rpped.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.phppediatria@spsp.org.br||rpp@spsp.org.br1984-04620103-0582opendoar:2015-09-01T00:00Revista Paulista de Pediatria (Ed. Português. Online) - Sociedade de Pediatria de São Paulo (SPSP)false
dc.title.none.fl_str_mv Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
title Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
spellingShingle Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
Mourato,Felipe Alves
hypertension, pulmonary
heart defects, congenital
Down syndrome
title_short Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
title_full Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
title_fullStr Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
title_full_unstemmed Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
title_sort Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service
author Mourato,Felipe Alves
author_facet Mourato,Felipe Alves
Villachan,Lúcia Roberta R.
Mattos,Sandra da Silva
author_role author
author2 Villachan,Lúcia Roberta R.
Mattos,Sandra da Silva
author2_role author
author
dc.contributor.author.fl_str_mv Mourato,Felipe Alves
Villachan,Lúcia Roberta R.
Mattos,Sandra da Silva
dc.subject.por.fl_str_mv hypertension, pulmonary
heart defects, congenital
Down syndrome
topic hypertension, pulmonary
heart defects, congenital
Down syndrome
description OBJECTIVE:To determine the frequence and profile of congenital heart defects in Down syndrome patients referred to a pediatric cardiologic center, considering the age of referral, gender, type of heart disease diagnosed by transthoracic echocardiography and its association with pulmonary hypertension at the initial diagnosis.METHODS:Cross-sectional study with retrospective data collection of 138 patients with Down syndrome from a total of 17,873 records. Descriptive analysis of the data was performed, using Epi-Info version 7.RESULTS: Among the 138 patients with Down syndrome, females prevailed (56.1%) and 112 (81.2%) were diagnosed with congenital heart disease. The most common lesion was ostium secundum atrial septal defect, present in 51.8%, followed by atrioventricular septal defect, in 46.4%. Ventricular septal defects were present in 27.7%, while tetralogy of Fallot represented 6.3% of the cases. Other cardiac malformations corresponded to 12.5%. Pulmonary hypertension was associated with 37.5% of the heart diseases. Only 35.5% of the patients were referred before six months of age.CONCLUSIONS: The low percentage of referral until six months of age highlights the need for a better tracking of patients with Down syndrome in the context of congenital heart disease, due to the high frequency and progression of pulmonary hypertension.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822014000200159
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0103-0582201432218913
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade de Pediatria de São Paulo
publisher.none.fl_str_mv Sociedade de Pediatria de São Paulo
dc.source.none.fl_str_mv Revista Paulista de Pediatria v.32 n.2 2014
reponame:Revista Paulista de Pediatria (Ed. Português. Online)
instname:Sociedade de Pediatria de São Paulo (SPSP)
instacron:SPSP
instname_str Sociedade de Pediatria de São Paulo (SPSP)
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reponame_str Revista Paulista de Pediatria (Ed. Português. Online)
collection Revista Paulista de Pediatria (Ed. Português. Online)
repository.name.fl_str_mv Revista Paulista de Pediatria (Ed. Português. Online) - Sociedade de Pediatria de São Paulo (SPSP)
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