Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents

Detalhes bibliográficos
Autor(a) principal: Clemente,Ana Paula Grotti
Data de Publicação: 2016
Outros Autores: Dal Molin Netto,Bárbara, Carvalho-Ferreira,Joana Pereira de, Campos,Raquel Munhoz da Silveira, Ganen,Aline de Piano, Tock,Lian, Mello,Marco Túlio de, Dâmaso,Ana Raimunda
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Paulista de Pediatria (Ed. Português. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822016000100047
Resumo: Abstract Objective: To assess the relationship between the degree of waist circumference (WC) and nonalcoholic fatty liver disease (NAFLD) in obese adolescents of both genders, analyzed according to quartiles of WC. Methods: Cross-sectional study that involved 247 obese adolescents aged 12–19 years. Mean values of the nutritional parameters and serum analyses were compared with the groups using the independent t-test. Pearson correlation coefficient was used to determine the relationship of the parameters studied. Chi-square test for trend was used to determine the relationship between the prevalence of the NAFLD and WC quartile by gender. Results: NAFLD were presented in 60% of the study participants. Obese adolescents in the 3rd and 4th quartiles of WC presented higher prevalence of NAFLD when compared with that in the 1st quartile in both genders. The NAFLD patients had significantly higher values for body weight, BMI (body mass index), BAZ-score (BMI-for-age z-scores), total fat (% and kg), WC, visceral fat, insulin, insulin resistance index (HOMA-IR), aspartate aminotransferase and alanine aminotransferase, when compared with non-NAFLD obese adolescents. Conclusions: In conclusion, the results presented here suggest that an increase in WC can reliably predict the risk of NAFLD in obese adolescents. This is a low cost and easy-to-use tool that can help in screening in adolescents.
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spelling Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescentsAspartate aminotransferaseAlanine aminotransferaseAbdominal fatAdolescentsAbstract Objective: To assess the relationship between the degree of waist circumference (WC) and nonalcoholic fatty liver disease (NAFLD) in obese adolescents of both genders, analyzed according to quartiles of WC. Methods: Cross-sectional study that involved 247 obese adolescents aged 12–19 years. Mean values of the nutritional parameters and serum analyses were compared with the groups using the independent t-test. Pearson correlation coefficient was used to determine the relationship of the parameters studied. Chi-square test for trend was used to determine the relationship between the prevalence of the NAFLD and WC quartile by gender. Results: NAFLD were presented in 60% of the study participants. Obese adolescents in the 3rd and 4th quartiles of WC presented higher prevalence of NAFLD when compared with that in the 1st quartile in both genders. The NAFLD patients had significantly higher values for body weight, BMI (body mass index), BAZ-score (BMI-for-age z-scores), total fat (% and kg), WC, visceral fat, insulin, insulin resistance index (HOMA-IR), aspartate aminotransferase and alanine aminotransferase, when compared with non-NAFLD obese adolescents. Conclusions: In conclusion, the results presented here suggest that an increase in WC can reliably predict the risk of NAFLD in obese adolescents. This is a low cost and easy-to-use tool that can help in screening in adolescents.Sociedade de Pediatria de São Paulo2016-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822016000100047Revista Paulista de Pediatria v.34 n.1 2016reponame:Revista Paulista de Pediatria (Ed. Português. Online)instname:Sociedade de Pediatria de São Paulo (SPSP)instacron:SPSP10.1016/j.rppede.2015.10.004info:eu-repo/semantics/openAccessClemente,Ana Paula GrottiDal Molin Netto,BárbaraCarvalho-Ferreira,Joana Pereira deCampos,Raquel Munhoz da SilveiraGanen,Aline de PianoTock,LianMello,Marco Túlio deDâmaso,Ana Raimundaeng2018-04-03T00:00:00Zoai:scielo:S0103-05822016000100047Revistahttps://www.rpped.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.phppediatria@spsp.org.br||rpp@spsp.org.br1984-04620103-0582opendoar:2018-04-03T00:00Revista Paulista de Pediatria (Ed. Português. Online) - Sociedade de Pediatria de São Paulo (SPSP)false
dc.title.none.fl_str_mv Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
title Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
spellingShingle Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
Clemente,Ana Paula Grotti
Aspartate aminotransferase
Alanine aminotransferase
Abdominal fat
Adolescents
title_short Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
title_full Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
title_fullStr Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
title_full_unstemmed Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
title_sort Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents
author Clemente,Ana Paula Grotti
author_facet Clemente,Ana Paula Grotti
Dal Molin Netto,Bárbara
Carvalho-Ferreira,Joana Pereira de
Campos,Raquel Munhoz da Silveira
Ganen,Aline de Piano
Tock,Lian
Mello,Marco Túlio de
Dâmaso,Ana Raimunda
author_role author
author2 Dal Molin Netto,Bárbara
Carvalho-Ferreira,Joana Pereira de
Campos,Raquel Munhoz da Silveira
Ganen,Aline de Piano
Tock,Lian
Mello,Marco Túlio de
Dâmaso,Ana Raimunda
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Clemente,Ana Paula Grotti
Dal Molin Netto,Bárbara
Carvalho-Ferreira,Joana Pereira de
Campos,Raquel Munhoz da Silveira
Ganen,Aline de Piano
Tock,Lian
Mello,Marco Túlio de
Dâmaso,Ana Raimunda
dc.subject.por.fl_str_mv Aspartate aminotransferase
Alanine aminotransferase
Abdominal fat
Adolescents
topic Aspartate aminotransferase
Alanine aminotransferase
Abdominal fat
Adolescents
description Abstract Objective: To assess the relationship between the degree of waist circumference (WC) and nonalcoholic fatty liver disease (NAFLD) in obese adolescents of both genders, analyzed according to quartiles of WC. Methods: Cross-sectional study that involved 247 obese adolescents aged 12–19 years. Mean values of the nutritional parameters and serum analyses were compared with the groups using the independent t-test. Pearson correlation coefficient was used to determine the relationship of the parameters studied. Chi-square test for trend was used to determine the relationship between the prevalence of the NAFLD and WC quartile by gender. Results: NAFLD were presented in 60% of the study participants. Obese adolescents in the 3rd and 4th quartiles of WC presented higher prevalence of NAFLD when compared with that in the 1st quartile in both genders. The NAFLD patients had significantly higher values for body weight, BMI (body mass index), BAZ-score (BMI-for-age z-scores), total fat (% and kg), WC, visceral fat, insulin, insulin resistance index (HOMA-IR), aspartate aminotransferase and alanine aminotransferase, when compared with non-NAFLD obese adolescents. Conclusions: In conclusion, the results presented here suggest that an increase in WC can reliably predict the risk of NAFLD in obese adolescents. This is a low cost and easy-to-use tool that can help in screening in adolescents.
publishDate 2016
dc.date.none.fl_str_mv 2016-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822016000100047
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822016000100047
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.rppede.2015.10.004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade de Pediatria de São Paulo
publisher.none.fl_str_mv Sociedade de Pediatria de São Paulo
dc.source.none.fl_str_mv Revista Paulista de Pediatria v.34 n.1 2016
reponame:Revista Paulista de Pediatria (Ed. Português. Online)
instname:Sociedade de Pediatria de São Paulo (SPSP)
instacron:SPSP
instname_str Sociedade de Pediatria de São Paulo (SPSP)
instacron_str SPSP
institution SPSP
reponame_str Revista Paulista de Pediatria (Ed. Português. Online)
collection Revista Paulista de Pediatria (Ed. Português. Online)
repository.name.fl_str_mv Revista Paulista de Pediatria (Ed. Português. Online) - Sociedade de Pediatria de São Paulo (SPSP)
repository.mail.fl_str_mv pediatria@spsp.org.br||rpp@spsp.org.br
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