Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2005 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Brazilian Archives of Biology and Technology |
| Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000200007 |
Resumo: | The antiulcer activity of a hydro-ethanolic extract prepared from the stems of Kielmeyera coriacea Mart. (Guttiferae) was evaluated in rats employing the ethanol-acid, acute stress and Indomethacin models to induce experimental gastric ulcers. Treatment with K coriacea hydro-ethanolic extract provided significant antiulcer protection in the ethanol-acid and Indomethacin models, but not in the acute stress model. These results suggested that the K coriacea hydro-ethanolic extract increased resistance to necrotizing agents, providing a direct, protective effect on the gastric mucosa. |
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Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriaceaAcute stressanti-ulcer activityethanol-acidIndomethacinKielmeyera coriacea Mart. (Guttiferae)The antiulcer activity of a hydro-ethanolic extract prepared from the stems of Kielmeyera coriacea Mart. (Guttiferae) was evaluated in rats employing the ethanol-acid, acute stress and Indomethacin models to induce experimental gastric ulcers. Treatment with K coriacea hydro-ethanolic extract provided significant antiulcer protection in the ethanol-acid and Indomethacin models, but not in the acute stress model. These results suggested that the K coriacea hydro-ethanolic extract increased resistance to necrotizing agents, providing a direct, protective effect on the gastric mucosa.Instituto de Tecnologia do Paraná - Tecpar2005-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000200007Brazilian Archives of Biology and Technology v.48 n.2 2005reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132005000200007info:eu-repo/semantics/openAccessGoulart,Yara Cavalcante FortesSela,Vania RamosObici,SimoniMartins,Juliana Vanessa ColomboOtobone,FernandaCortez,Diogenes AparicioAudi,Elisabeth Aparecidaeng2005-04-26T00:00:00Zoai:scielo:S1516-89132005000200007Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2005-04-26T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
| dc.title.none.fl_str_mv |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea |
| title |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea |
| spellingShingle |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea Goulart,Yara Cavalcante Fortes Acute stress anti-ulcer activity ethanol-acid Indomethacin Kielmeyera coriacea Mart. (Guttiferae) |
| title_short |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea |
| title_full |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea |
| title_fullStr |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea |
| title_full_unstemmed |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea |
| title_sort |
Evaluation of gastric anti-ulcer activity in a hydro-ethanolic extract from Kielmeyera coriacea |
| author |
Goulart,Yara Cavalcante Fortes |
| author_facet |
Goulart,Yara Cavalcante Fortes Sela,Vania Ramos Obici,Simoni Martins,Juliana Vanessa Colombo Otobone,Fernanda Cortez,Diogenes Aparicio Audi,Elisabeth Aparecida |
| author_role |
author |
| author2 |
Sela,Vania Ramos Obici,Simoni Martins,Juliana Vanessa Colombo Otobone,Fernanda Cortez,Diogenes Aparicio Audi,Elisabeth Aparecida |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Goulart,Yara Cavalcante Fortes Sela,Vania Ramos Obici,Simoni Martins,Juliana Vanessa Colombo Otobone,Fernanda Cortez,Diogenes Aparicio Audi,Elisabeth Aparecida |
| dc.subject.por.fl_str_mv |
Acute stress anti-ulcer activity ethanol-acid Indomethacin Kielmeyera coriacea Mart. (Guttiferae) |
| topic |
Acute stress anti-ulcer activity ethanol-acid Indomethacin Kielmeyera coriacea Mart. (Guttiferae) |
| description |
The antiulcer activity of a hydro-ethanolic extract prepared from the stems of Kielmeyera coriacea Mart. (Guttiferae) was evaluated in rats employing the ethanol-acid, acute stress and Indomethacin models to induce experimental gastric ulcers. Treatment with K coriacea hydro-ethanolic extract provided significant antiulcer protection in the ethanol-acid and Indomethacin models, but not in the acute stress model. These results suggested that the K coriacea hydro-ethanolic extract increased resistance to necrotizing agents, providing a direct, protective effect on the gastric mucosa. |
| publishDate |
2005 |
| dc.date.none.fl_str_mv |
2005-03-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000200007 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000200007 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1590/S1516-89132005000200007 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
text/html |
| dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
| publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
| dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.48 n.2 2005 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
| instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
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TECPAR |
| institution |
TECPAR |
| reponame_str |
Brazilian Archives of Biology and Technology |
| collection |
Brazilian Archives of Biology and Technology |
| repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
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babt@tecpar.br||babt@tecpar.br |
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1750318270239473664 |