Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review

Detalhes bibliográficos
Autor(a) principal: Miranda,Ana Cláudia Camargo
Data de Publicação: 2019
Outros Autores: Durante,Ana Claudia Ranucci, Fuscaldi,Leonardo Lima, Barboza,Marycel Figols de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100903
Resumo: Abstract To present optimized chromatographic systems for radiochemical purity (RCP) evaluation of 99mTc-eluate and 99mTc-radiopharmaceuticals, as well as to assess doses calibrator reliability for routine purposes in hospital radiopharmacies. RCP was determined by different systems and radioactivity was quantified by TLC-scanner, doses calibrator and gamma-counter. Suitable and optimized systems were presented for RCP analyses. No significant differences were observed between radioactivity counting devices and, thus, doses calibrator showed reliability for RCP determination in hospital radiopharmacies.
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spelling Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review99mTc-radiopharmaceuticalsRadiochemical purityAscendant chromatographyChromatographic systemDose calibratorAbstract To present optimized chromatographic systems for radiochemical purity (RCP) evaluation of 99mTc-eluate and 99mTc-radiopharmaceuticals, as well as to assess doses calibrator reliability for routine purposes in hospital radiopharmacies. RCP was determined by different systems and radioactivity was quantified by TLC-scanner, doses calibrator and gamma-counter. Suitable and optimized systems were presented for RCP analyses. No significant differences were observed between radioactivity counting devices and, thus, doses calibrator showed reliability for RCP determination in hospital radiopharmacies.Instituto de Tecnologia do Paraná - Tecpar2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100903Brazilian Archives of Biology and Technology v.62 2019reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2019180545info:eu-repo/semantics/openAccessMiranda,Ana Cláudia CamargoDurante,Ana Claudia RanucciFuscaldi,Leonardo LimaBarboza,Marycel Figols deeng2019-09-05T00:00:00Zoai:scielo:S1516-89132019000100903Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2019-09-05T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
title Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
spellingShingle Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
Miranda,Ana Cláudia Camargo
99mTc-radiopharmaceuticals
Radiochemical purity
Ascendant chromatography
Chromatographic system
Dose calibrator
title_short Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
title_full Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
title_fullStr Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
title_full_unstemmed Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
title_sort Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review
author Miranda,Ana Cláudia Camargo
author_facet Miranda,Ana Cláudia Camargo
Durante,Ana Claudia Ranucci
Fuscaldi,Leonardo Lima
Barboza,Marycel Figols de
author_role author
author2 Durante,Ana Claudia Ranucci
Fuscaldi,Leonardo Lima
Barboza,Marycel Figols de
author2_role author
author
author
dc.contributor.author.fl_str_mv Miranda,Ana Cláudia Camargo
Durante,Ana Claudia Ranucci
Fuscaldi,Leonardo Lima
Barboza,Marycel Figols de
dc.subject.por.fl_str_mv 99mTc-radiopharmaceuticals
Radiochemical purity
Ascendant chromatography
Chromatographic system
Dose calibrator
topic 99mTc-radiopharmaceuticals
Radiochemical purity
Ascendant chromatography
Chromatographic system
Dose calibrator
description Abstract To present optimized chromatographic systems for radiochemical purity (RCP) evaluation of 99mTc-eluate and 99mTc-radiopharmaceuticals, as well as to assess doses calibrator reliability for routine purposes in hospital radiopharmacies. RCP was determined by different systems and radioactivity was quantified by TLC-scanner, doses calibrator and gamma-counter. Suitable and optimized systems were presented for RCP analyses. No significant differences were observed between radioactivity counting devices and, thus, doses calibrator showed reliability for RCP determination in hospital radiopharmacies.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100903
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100903
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4324-2019180545
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.62 2019
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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