Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000300005 |
Resumo: | This study aimed to evaluate the anti-inflammatory and repair effects of the ethanolic extract and ointment of Equisetum pyramidale on the skin lesions of rats induced to diabetes. After the induction of diabetes with alloxan, a surgical procedure was performed on the back of each rat. Then, they were separated into treatment groups: G1 ethanol extract of E. pyramidale; G2-ointment (extract of E. pyramidale 80g + 20g of vaseline:lanolin 1:1); G3 control (vehicle vaseline:lanolin 1:1); and G4-no treatment during 3, 7 and 14 days. The samples were embedded in paraffin and stained with hematoxylin-eosin for histological analysis. The findings showed that the use of ethanolic extract as well as the ointment decreased the inflammatory cells at the site of inflammation, resulting a faster healing, with less crusting and lower amount of secretion in comparison to the control group. Therapy with topical herbal was an effective method in the inflammatory process of tissue repair, contributing to a faster and more organized tissue re-epithelialization. |
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Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic ratsDiabetesskin lesionsmedicinal plantsanti-inflammatory activityreepithelialization tissueThis study aimed to evaluate the anti-inflammatory and repair effects of the ethanolic extract and ointment of Equisetum pyramidale on the skin lesions of rats induced to diabetes. After the induction of diabetes with alloxan, a surgical procedure was performed on the back of each rat. Then, they were separated into treatment groups: G1 ethanol extract of E. pyramidale; G2-ointment (extract of E. pyramidale 80g + 20g of vaseline:lanolin 1:1); G3 control (vehicle vaseline:lanolin 1:1); and G4-no treatment during 3, 7 and 14 days. The samples were embedded in paraffin and stained with hematoxylin-eosin for histological analysis. The findings showed that the use of ethanolic extract as well as the ointment decreased the inflammatory cells at the site of inflammation, resulting a faster healing, with less crusting and lower amount of secretion in comparison to the control group. Therapy with topical herbal was an effective method in the inflammatory process of tissue repair, contributing to a faster and more organized tissue re-epithelialization.Instituto de Tecnologia do Paraná - Tecpar2013-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000300005Brazilian Archives of Biology and Technology v.56 n.3 2013reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132013000300005info:eu-repo/semantics/openAccessCorrêa,Andréia Cristina LopesHans Filho,GuinterDourado,Doroty MesquitaMatias,RosemarySilva,Iandara Schettert daSarragiotto,Maria Helenaeng2013-07-12T00:00:00Zoai:scielo:S1516-89132013000300005Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2013-07-12T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats |
title |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats |
spellingShingle |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats Corrêa,Andréia Cristina Lopes Diabetes skin lesions medicinal plants anti-inflammatory activity reepithelialization tissue |
title_short |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats |
title_full |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats |
title_fullStr |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats |
title_full_unstemmed |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats |
title_sort |
Healing effect of the ointment made of Equisetum pyramidale in the treatment of cutaneous lesions in diabetic rats |
author |
Corrêa,Andréia Cristina Lopes |
author_facet |
Corrêa,Andréia Cristina Lopes Hans Filho,Guinter Dourado,Doroty Mesquita Matias,Rosemary Silva,Iandara Schettert da Sarragiotto,Maria Helena |
author_role |
author |
author2 |
Hans Filho,Guinter Dourado,Doroty Mesquita Matias,Rosemary Silva,Iandara Schettert da Sarragiotto,Maria Helena |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Corrêa,Andréia Cristina Lopes Hans Filho,Guinter Dourado,Doroty Mesquita Matias,Rosemary Silva,Iandara Schettert da Sarragiotto,Maria Helena |
dc.subject.por.fl_str_mv |
Diabetes skin lesions medicinal plants anti-inflammatory activity reepithelialization tissue |
topic |
Diabetes skin lesions medicinal plants anti-inflammatory activity reepithelialization tissue |
description |
This study aimed to evaluate the anti-inflammatory and repair effects of the ethanolic extract and ointment of Equisetum pyramidale on the skin lesions of rats induced to diabetes. After the induction of diabetes with alloxan, a surgical procedure was performed on the back of each rat. Then, they were separated into treatment groups: G1 ethanol extract of E. pyramidale; G2-ointment (extract of E. pyramidale 80g + 20g of vaseline:lanolin 1:1); G3 control (vehicle vaseline:lanolin 1:1); and G4-no treatment during 3, 7 and 14 days. The samples were embedded in paraffin and stained with hematoxylin-eosin for histological analysis. The findings showed that the use of ethanolic extract as well as the ointment decreased the inflammatory cells at the site of inflammation, resulting a faster healing, with less crusting and lower amount of secretion in comparison to the control group. Therapy with topical herbal was an effective method in the inflammatory process of tissue repair, contributing to a faster and more organized tissue re-epithelialization. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000300005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000300005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132013000300005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.56 n.3 2013 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318275645931520 |