Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton

Detalhes bibliográficos
Autor(a) principal: Ricardo,Kelly Fabiane Santos
Data de Publicação: 2001
Outros Autores: Oliveira,Tânia Toledo de, Nagem,Tanus Jorge, Pinto,Aloisio da Silva, Oliveira,Maria Goreti Almeida, Soares,José Francisco
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132001000300007
Resumo: Atherosclerosis is a coronary disease where deposition of lipids in the arteries leads to problems of blood circulation. The present work evaluates the action of the flavonoids morin, quercetin and nicotinic acid isolated in association on lipid metabolism in hyperlipidemic rats. Blood serum levels cholesterol, cholesterol-HDL, and triacylglycerids have been analysed following the intraperitoneal administration of the flavonoid compounds dissolved in propyleneglycol by in doses of 5mg/kg body weight. Quercetin presented the largest percentual reduction of cholesterol. The best results for cholesterol-HDL have been obtained with-nicotinic acid alone while morin-nicotinic acid combination showed the best triacylglycerols results. Results showed that flavonoids could be beneficious in the treatment of coronary diseases.
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spelling Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with tritonMorinQuercetinNicotinic AcidLipidCholesterolCholesterol-HDLTriacylglycerolsRatsHyperlipidemicAtherosclerosis is a coronary disease where deposition of lipids in the arteries leads to problems of blood circulation. The present work evaluates the action of the flavonoids morin, quercetin and nicotinic acid isolated in association on lipid metabolism in hyperlipidemic rats. Blood serum levels cholesterol, cholesterol-HDL, and triacylglycerids have been analysed following the intraperitoneal administration of the flavonoid compounds dissolved in propyleneglycol by in doses of 5mg/kg body weight. Quercetin presented the largest percentual reduction of cholesterol. The best results for cholesterol-HDL have been obtained with-nicotinic acid alone while morin-nicotinic acid combination showed the best triacylglycerols results. Results showed that flavonoids could be beneficious in the treatment of coronary diseases.Instituto de Tecnologia do Paraná - Tecpar2001-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132001000300007Brazilian Archives of Biology and Technology v.44 n.3 2001reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132001000300007info:eu-repo/semantics/openAccessRicardo,Kelly Fabiane SantosOliveira,Tânia Toledo deNagem,Tanus JorgePinto,Aloisio da SilvaOliveira,Maria Goreti AlmeidaSoares,José Franciscoeng2002-01-23T00:00:00Zoai:scielo:S1516-89132001000300007Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2002-01-23T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
title Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
spellingShingle Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
Ricardo,Kelly Fabiane Santos
Morin
Quercetin
Nicotinic Acid
Lipid
Cholesterol
Cholesterol-HDL
Triacylglycerols
Rats
Hyperlipidemic
title_short Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
title_full Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
title_fullStr Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
title_full_unstemmed Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
title_sort Effect of flavonoids morin; quercetin and nicotinic acid on lipid metabolism of rats experimentally fed with triton
author Ricardo,Kelly Fabiane Santos
author_facet Ricardo,Kelly Fabiane Santos
Oliveira,Tânia Toledo de
Nagem,Tanus Jorge
Pinto,Aloisio da Silva
Oliveira,Maria Goreti Almeida
Soares,José Francisco
author_role author
author2 Oliveira,Tânia Toledo de
Nagem,Tanus Jorge
Pinto,Aloisio da Silva
Oliveira,Maria Goreti Almeida
Soares,José Francisco
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Ricardo,Kelly Fabiane Santos
Oliveira,Tânia Toledo de
Nagem,Tanus Jorge
Pinto,Aloisio da Silva
Oliveira,Maria Goreti Almeida
Soares,José Francisco
dc.subject.por.fl_str_mv Morin
Quercetin
Nicotinic Acid
Lipid
Cholesterol
Cholesterol-HDL
Triacylglycerols
Rats
Hyperlipidemic
topic Morin
Quercetin
Nicotinic Acid
Lipid
Cholesterol
Cholesterol-HDL
Triacylglycerols
Rats
Hyperlipidemic
description Atherosclerosis is a coronary disease where deposition of lipids in the arteries leads to problems of blood circulation. The present work evaluates the action of the flavonoids morin, quercetin and nicotinic acid isolated in association on lipid metabolism in hyperlipidemic rats. Blood serum levels cholesterol, cholesterol-HDL, and triacylglycerids have been analysed following the intraperitoneal administration of the flavonoid compounds dissolved in propyleneglycol by in doses of 5mg/kg body weight. Quercetin presented the largest percentual reduction of cholesterol. The best results for cholesterol-HDL have been obtained with-nicotinic acid alone while morin-nicotinic acid combination showed the best triacylglycerols results. Results showed that flavonoids could be beneficious in the treatment of coronary diseases.
publishDate 2001
dc.date.none.fl_str_mv 2001-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132001000300007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132001000300007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132001000300007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.44 n.3 2001
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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