Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis

Detalhes bibliográficos
Autor(a) principal: Gayoso,Carla Wanderley
Data de Publicação: 2006
Outros Autores: Lima,Edeltrudes de Oliveira, Souza,Evandro Leite de, Cechinel Filho,Valdir, Trajano,Vinícius Nogueira, Pereira,Fillipe de Oliveira, Lima,Igara Oliveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500016
Resumo: This study aimed to analyze the effectiveness of maleimides as inhibitors on the growth of fungal strains isolated from onychomycosis by the solid medium diffusion procedure. The results showed a promising antifungical activity of the assayed maleimides with formation of fungal growth inhibition halos oscillating between diameter 10 and 23mm. MIC was 100µg/mL for 3,4-dichloro-N-phenyl-methyl-maleimide and 3,4-dichloro-N-phenyl-propil-maleimide and 200µg/mL for 3,4-dichloro-N-phenyl-maleimide, 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-buthyl-maleimide.
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spelling Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosisOnychomycosisfungimaleimidesantifungical activityThis study aimed to analyze the effectiveness of maleimides as inhibitors on the growth of fungal strains isolated from onychomycosis by the solid medium diffusion procedure. The results showed a promising antifungical activity of the assayed maleimides with formation of fungal growth inhibition halos oscillating between diameter 10 and 23mm. MIC was 100µg/mL for 3,4-dichloro-N-phenyl-methyl-maleimide and 3,4-dichloro-N-phenyl-propil-maleimide and 200µg/mL for 3,4-dichloro-N-phenyl-maleimide, 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-buthyl-maleimide.Instituto de Tecnologia do Paraná - Tecpar2006-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500016Brazilian Archives of Biology and Technology v.49 n.4 2006reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132006000500016info:eu-repo/semantics/openAccessGayoso,Carla WanderleyLima,Edeltrudes de OliveiraSouza,Evandro Leite deCechinel Filho,ValdirTrajano,Vinícius NogueiraPereira,Fillipe de OliveiraLima,Igara Oliveiraeng2006-08-30T00:00:00Zoai:scielo:S1516-89132006000500016Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2006-08-30T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
title Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
spellingShingle Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
Gayoso,Carla Wanderley
Onychomycosis
fungi
maleimides
antifungical activity
title_short Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
title_full Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
title_fullStr Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
title_full_unstemmed Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
title_sort Antimicrobial effectiveness of maleimides on fungal strains isolated from onychomycosis
author Gayoso,Carla Wanderley
author_facet Gayoso,Carla Wanderley
Lima,Edeltrudes de Oliveira
Souza,Evandro Leite de
Cechinel Filho,Valdir
Trajano,Vinícius Nogueira
Pereira,Fillipe de Oliveira
Lima,Igara Oliveira
author_role author
author2 Lima,Edeltrudes de Oliveira
Souza,Evandro Leite de
Cechinel Filho,Valdir
Trajano,Vinícius Nogueira
Pereira,Fillipe de Oliveira
Lima,Igara Oliveira
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gayoso,Carla Wanderley
Lima,Edeltrudes de Oliveira
Souza,Evandro Leite de
Cechinel Filho,Valdir
Trajano,Vinícius Nogueira
Pereira,Fillipe de Oliveira
Lima,Igara Oliveira
dc.subject.por.fl_str_mv Onychomycosis
fungi
maleimides
antifungical activity
topic Onychomycosis
fungi
maleimides
antifungical activity
description This study aimed to analyze the effectiveness of maleimides as inhibitors on the growth of fungal strains isolated from onychomycosis by the solid medium diffusion procedure. The results showed a promising antifungical activity of the assayed maleimides with formation of fungal growth inhibition halos oscillating between diameter 10 and 23mm. MIC was 100µg/mL for 3,4-dichloro-N-phenyl-methyl-maleimide and 3,4-dichloro-N-phenyl-propil-maleimide and 200µg/mL for 3,4-dichloro-N-phenyl-maleimide, 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-buthyl-maleimide.
publishDate 2006
dc.date.none.fl_str_mv 2006-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500016
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132006000500016
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.49 n.4 2006
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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