Exosomes as Biomarker of Cancer
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100309 |
Resumo: | ABSTRACT Rapid advances in medicine and biotechnology resulted in the development of non-invasive diagnostic and prognostic biomarkers enabling convenient and accurate detection. Exosomes has recently emerged as non-invasive biomarker for a number of diseases including cancer. Exosomes are the small endosome originated membranous vesicles secreted in a number of biological fluids such as serum, saliva, urine, ascites, cerebrospinal fluid, etc. Exosomes contain microRNA proteins and mRNA which can be used as disease specific biomarkers. Here we reviewed recent advancement in the field of exosomes as diagnostic biomarker for cancer along with a brief overview of their biogenesis, function and isolation. |
id |
TECPAR-1_5656214755b05b43db56175c76a074ec |
---|---|
oai_identifier_str |
oai:scielo:S1516-89132018000100309 |
network_acronym_str |
TECPAR-1 |
network_name_str |
Brazilian Archives of Biology and Technology |
repository_id_str |
|
spelling |
Exosomes as Biomarker of CancerExosomeBiomarkerCancer biomarkerABSTRACT Rapid advances in medicine and biotechnology resulted in the development of non-invasive diagnostic and prognostic biomarkers enabling convenient and accurate detection. Exosomes has recently emerged as non-invasive biomarker for a number of diseases including cancer. Exosomes are the small endosome originated membranous vesicles secreted in a number of biological fluids such as serum, saliva, urine, ascites, cerebrospinal fluid, etc. Exosomes contain microRNA proteins and mRNA which can be used as disease specific biomarkers. Here we reviewed recent advancement in the field of exosomes as diagnostic biomarker for cancer along with a brief overview of their biogenesis, function and isolation.Instituto de Tecnologia do Paraná - Tecpar2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100309Brazilian Archives of Biology and Technology v.61 2018reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2018160730info:eu-repo/semantics/openAccessSumrin,AleenaMoazzam,ShumailaKhan,Aleena AhmadRamzan,IrsaBatool,ZunairaKaleem,SanaAli,MoazzamBashir,HamidBilal,Muhammadeng2018-10-04T00:00:00Zoai:scielo:S1516-89132018000100309Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2018-10-04T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Exosomes as Biomarker of Cancer |
title |
Exosomes as Biomarker of Cancer |
spellingShingle |
Exosomes as Biomarker of Cancer Sumrin,Aleena Exosome Biomarker Cancer biomarker |
title_short |
Exosomes as Biomarker of Cancer |
title_full |
Exosomes as Biomarker of Cancer |
title_fullStr |
Exosomes as Biomarker of Cancer |
title_full_unstemmed |
Exosomes as Biomarker of Cancer |
title_sort |
Exosomes as Biomarker of Cancer |
author |
Sumrin,Aleena |
author_facet |
Sumrin,Aleena Moazzam,Shumaila Khan,Aleena Ahmad Ramzan,Irsa Batool,Zunaira Kaleem,Sana Ali,Moazzam Bashir,Hamid Bilal,Muhammad |
author_role |
author |
author2 |
Moazzam,Shumaila Khan,Aleena Ahmad Ramzan,Irsa Batool,Zunaira Kaleem,Sana Ali,Moazzam Bashir,Hamid Bilal,Muhammad |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Sumrin,Aleena Moazzam,Shumaila Khan,Aleena Ahmad Ramzan,Irsa Batool,Zunaira Kaleem,Sana Ali,Moazzam Bashir,Hamid Bilal,Muhammad |
dc.subject.por.fl_str_mv |
Exosome Biomarker Cancer biomarker |
topic |
Exosome Biomarker Cancer biomarker |
description |
ABSTRACT Rapid advances in medicine and biotechnology resulted in the development of non-invasive diagnostic and prognostic biomarkers enabling convenient and accurate detection. Exosomes has recently emerged as non-invasive biomarker for a number of diseases including cancer. Exosomes are the small endosome originated membranous vesicles secreted in a number of biological fluids such as serum, saliva, urine, ascites, cerebrospinal fluid, etc. Exosomes contain microRNA proteins and mRNA which can be used as disease specific biomarkers. Here we reviewed recent advancement in the field of exosomes as diagnostic biomarker for cancer along with a brief overview of their biogenesis, function and isolation. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100309 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100309 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-4324-2018160730 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.61 2018 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318278608158720 |