Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol

Detalhes bibliográficos
Autor(a) principal: Erdönmez,Demet
Data de Publicação: 2018
Outros Autores: Rad,Abbas Yousefi, Aksöz,Nilüfer
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100403
Resumo: ABSTRACT Quorum sensing system plays an active role in the regulation of pathogenicity of many microorganisms. Inhibition of pathogenicity or virulence factors will increase the success of treatment by preventing the development of antibiotic resistance. In this study, anti-quorum sensing activities of quercetin and resveratrol compounds, which have antioxidant property without damaging to host, have been determined via using biosensor bacteria: Chromobacterium violaceum ATCC 12472 and Chromobacterium violaceum CV026. As quorum sensing inhibitors, quercetin and resveratrol's cutting off the bacterial communication will prevent the treatment failures caused by the development of bacterial resistance. The development of layered drugs with antioxidant compounds such as quercetin and resveratrol will pave the way for new horizons for new therapeutic strategies.
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spelling Anti-Quorum Sensing Potential of Antioxidant Quercetin and ResveratrolAnti-quorum sensingResveratrolQuercetinAntioxidantABSTRACT Quorum sensing system plays an active role in the regulation of pathogenicity of many microorganisms. Inhibition of pathogenicity or virulence factors will increase the success of treatment by preventing the development of antibiotic resistance. In this study, anti-quorum sensing activities of quercetin and resveratrol compounds, which have antioxidant property without damaging to host, have been determined via using biosensor bacteria: Chromobacterium violaceum ATCC 12472 and Chromobacterium violaceum CV026. As quorum sensing inhibitors, quercetin and resveratrol's cutting off the bacterial communication will prevent the treatment failures caused by the development of bacterial resistance. The development of layered drugs with antioxidant compounds such as quercetin and resveratrol will pave the way for new horizons for new therapeutic strategies.Instituto de Tecnologia do Paraná - Tecpar2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100403Brazilian Archives of Biology and Technology v.61 2018reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2017160756info:eu-repo/semantics/openAccessErdönmez,DemetRad,Abbas YousefiAksöz,Nilüfereng2018-06-21T00:00:00Zoai:scielo:S1516-89132018000100403Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2018-06-21T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
title Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
spellingShingle Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
Erdönmez,Demet
Anti-quorum sensing
Resveratrol
Quercetin
Antioxidant
title_short Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
title_full Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
title_fullStr Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
title_full_unstemmed Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
title_sort Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
author Erdönmez,Demet
author_facet Erdönmez,Demet
Rad,Abbas Yousefi
Aksöz,Nilüfer
author_role author
author2 Rad,Abbas Yousefi
Aksöz,Nilüfer
author2_role author
author
dc.contributor.author.fl_str_mv Erdönmez,Demet
Rad,Abbas Yousefi
Aksöz,Nilüfer
dc.subject.por.fl_str_mv Anti-quorum sensing
Resveratrol
Quercetin
Antioxidant
topic Anti-quorum sensing
Resveratrol
Quercetin
Antioxidant
description ABSTRACT Quorum sensing system plays an active role in the regulation of pathogenicity of many microorganisms. Inhibition of pathogenicity or virulence factors will increase the success of treatment by preventing the development of antibiotic resistance. In this study, anti-quorum sensing activities of quercetin and resveratrol compounds, which have antioxidant property without damaging to host, have been determined via using biosensor bacteria: Chromobacterium violaceum ATCC 12472 and Chromobacterium violaceum CV026. As quorum sensing inhibitors, quercetin and resveratrol's cutting off the bacterial communication will prevent the treatment failures caused by the development of bacterial resistance. The development of layered drugs with antioxidant compounds such as quercetin and resveratrol will pave the way for new horizons for new therapeutic strategies.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100403
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100403
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4324-2017160756
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.61 2018
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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