Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc

Detalhes bibliográficos
Autor(a) principal: Moraes,Vanessa
Data de Publicação: 2005
Outros Autores: Marczewski,Bárbara, Dias,Carla Roberta, Osso Junior,João Alberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700007
Resumo: 99mTc has ideal nuclear properties for organ imaging in nuclear medicine, and it is obtained from the 99Mo-99mTc generator. Four different types of generators are available: chromatographic that uses 99Mo from fission of uranium; MEK solvent extraction; Tc2O7 sublimation; gel chromatographic. This work presents the preparation of gel generators of molybdenum with cerium and characterization of the gels: mass ratio between molybdenum and cerium, structure, size of particles and elution percentage of 99mTc after irradiating the gels. Eight gels were prepared at the same temperature of 50 ºC with concentrations of NaOH of 2 and 4 mol/L, mass ratio of 0.31 and 0.38 and final pH of 3.5 and 4.5. The analysis of the results proved that these gels are not adequate for preparation of the generators of 99Mo-99mTc, since the elution percentages are low, when compared with the gel of molybdenum with zirconium.
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spelling Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTcRadioisotopestechnetium-99mmolybdenum-99gel generator99mTc has ideal nuclear properties for organ imaging in nuclear medicine, and it is obtained from the 99Mo-99mTc generator. Four different types of generators are available: chromatographic that uses 99Mo from fission of uranium; MEK solvent extraction; Tc2O7 sublimation; gel chromatographic. This work presents the preparation of gel generators of molybdenum with cerium and characterization of the gels: mass ratio between molybdenum and cerium, structure, size of particles and elution percentage of 99mTc after irradiating the gels. Eight gels were prepared at the same temperature of 50 ºC with concentrations of NaOH of 2 and 4 mol/L, mass ratio of 0.31 and 0.38 and final pH of 3.5 and 4.5. The analysis of the results proved that these gels are not adequate for preparation of the generators of 99Mo-99mTc, since the elution percentages are low, when compared with the gel of molybdenum with zirconium.Instituto de Tecnologia do Paraná - Tecpar2005-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700007Brazilian Archives of Biology and Technology v.48 n.spe2 2005reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132005000700007info:eu-repo/semantics/openAccessMoraes,VanessaMarczewski,BárbaraDias,Carla RobertaOsso Junior,João Albertoeng2005-12-09T00:00:00Zoai:scielo:S1516-89132005000700007Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2005-12-09T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
title Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
spellingShingle Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
Moraes,Vanessa
Radioisotopes
technetium-99m
molybdenum-99
gel generator
title_short Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
title_full Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
title_fullStr Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
title_full_unstemmed Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
title_sort Study of gels of molybdenum with cerium in the preparation of generators of 99Mo - 99mTc
author Moraes,Vanessa
author_facet Moraes,Vanessa
Marczewski,Bárbara
Dias,Carla Roberta
Osso Junior,João Alberto
author_role author
author2 Marczewski,Bárbara
Dias,Carla Roberta
Osso Junior,João Alberto
author2_role author
author
author
dc.contributor.author.fl_str_mv Moraes,Vanessa
Marczewski,Bárbara
Dias,Carla Roberta
Osso Junior,João Alberto
dc.subject.por.fl_str_mv Radioisotopes
technetium-99m
molybdenum-99
gel generator
topic Radioisotopes
technetium-99m
molybdenum-99
gel generator
description 99mTc has ideal nuclear properties for organ imaging in nuclear medicine, and it is obtained from the 99Mo-99mTc generator. Four different types of generators are available: chromatographic that uses 99Mo from fission of uranium; MEK solvent extraction; Tc2O7 sublimation; gel chromatographic. This work presents the preparation of gel generators of molybdenum with cerium and characterization of the gels: mass ratio between molybdenum and cerium, structure, size of particles and elution percentage of 99mTc after irradiating the gels. Eight gels were prepared at the same temperature of 50 ºC with concentrations of NaOH of 2 and 4 mol/L, mass ratio of 0.31 and 0.38 and final pH of 3.5 and 4.5. The analysis of the results proved that these gels are not adequate for preparation of the generators of 99Mo-99mTc, since the elution percentages are low, when compared with the gel of molybdenum with zirconium.
publishDate 2005
dc.date.none.fl_str_mv 2005-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132005000700007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.48 n.spe2 2005
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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