Modulation of post-coital dopaminergic tone by prior parity

Detalhes bibliográficos
Autor(a) principal: Sider,Lucia Helena
Data de Publicação: 2010
Outros Autores: Hucke,Erica Engelberg Teixeira da Silva, Felicio,Luciano Freitas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000300015
Resumo: The aim of this study was to investigate the possible effects of reproductive experience on dopaminergic profile in three different brain tissues, hypothalamus, striatum and cortex in rats on 7th-8th day of pregnancy during the light-dark shift (between 1700-1900h). Results showed that in hypothalamus, dopamine levels increased and DOPAC/DA decreased as a function of parity. In cortex, no differences were observed. In striata, the haloperidol-induced HVA and HVA/DA increases were less intense in experienced animals. These findings suggested that reproductive experience produced functional central changes during pregnancy, with different neurochemical responses depending on the brain region.
id TECPAR-1_7aa2435396563a351b5c0c26464a3c91
oai_identifier_str oai:scielo:S1516-89132010000300015
network_acronym_str TECPAR-1
network_name_str Brazilian Archives of Biology and Technology
repository_id_str
spelling Modulation of post-coital dopaminergic tone by prior parityhypothalamusstriatumcortexhaloperidolHVADOPACThe aim of this study was to investigate the possible effects of reproductive experience on dopaminergic profile in three different brain tissues, hypothalamus, striatum and cortex in rats on 7th-8th day of pregnancy during the light-dark shift (between 1700-1900h). Results showed that in hypothalamus, dopamine levels increased and DOPAC/DA decreased as a function of parity. In cortex, no differences were observed. In striata, the haloperidol-induced HVA and HVA/DA increases were less intense in experienced animals. These findings suggested that reproductive experience produced functional central changes during pregnancy, with different neurochemical responses depending on the brain region.Instituto de Tecnologia do Paraná - Tecpar2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000300015Brazilian Archives of Biology and Technology v.53 n.3 2010reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132010000300015info:eu-repo/semantics/openAccessSider,Lucia HelenaHucke,Erica Engelberg Teixeira da SilvaFelicio,Luciano Freitaseng2010-06-11T00:00:00Zoai:scielo:S1516-89132010000300015Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2010-06-11T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Modulation of post-coital dopaminergic tone by prior parity
title Modulation of post-coital dopaminergic tone by prior parity
spellingShingle Modulation of post-coital dopaminergic tone by prior parity
Sider,Lucia Helena
hypothalamus
striatum
cortex
haloperidol
HVA
DOPAC
title_short Modulation of post-coital dopaminergic tone by prior parity
title_full Modulation of post-coital dopaminergic tone by prior parity
title_fullStr Modulation of post-coital dopaminergic tone by prior parity
title_full_unstemmed Modulation of post-coital dopaminergic tone by prior parity
title_sort Modulation of post-coital dopaminergic tone by prior parity
author Sider,Lucia Helena
author_facet Sider,Lucia Helena
Hucke,Erica Engelberg Teixeira da Silva
Felicio,Luciano Freitas
author_role author
author2 Hucke,Erica Engelberg Teixeira da Silva
Felicio,Luciano Freitas
author2_role author
author
dc.contributor.author.fl_str_mv Sider,Lucia Helena
Hucke,Erica Engelberg Teixeira da Silva
Felicio,Luciano Freitas
dc.subject.por.fl_str_mv hypothalamus
striatum
cortex
haloperidol
HVA
DOPAC
topic hypothalamus
striatum
cortex
haloperidol
HVA
DOPAC
description The aim of this study was to investigate the possible effects of reproductive experience on dopaminergic profile in three different brain tissues, hypothalamus, striatum and cortex in rats on 7th-8th day of pregnancy during the light-dark shift (between 1700-1900h). Results showed that in hypothalamus, dopamine levels increased and DOPAC/DA decreased as a function of parity. In cortex, no differences were observed. In striata, the haloperidol-induced HVA and HVA/DA increases were less intense in experienced animals. These findings suggested that reproductive experience produced functional central changes during pregnancy, with different neurochemical responses depending on the brain region.
publishDate 2010
dc.date.none.fl_str_mv 2010-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000300015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000300015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132010000300015
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.53 n.3 2010
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
_version_ 1750318273962967040

Registros relacionados