Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity

Detalhes bibliográficos
Autor(a) principal: Cortez,Lucia Elaine Ranieri
Data de Publicação: 2011
Outros Autores: Ferreira,Izabel Cristina Piloto, Lonardoni,Valdrinez Campana, Ferreira,Antonio Gilberto, Vieira,Paulo Cesar, Silva,Maria Fátima das Graças Fernandes da, Fernandes,João Batista, Cortez,Diógenes Aparicio Garcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100008
Resumo: The dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine, sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with showed anti-leishmanial activity above 0.1 mg/mL and 75µg/mL (inhibited 50% promastigote growth), respectively.
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spelling Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activityAlmeidea coeruleaRutaceaeindolopyridoquinazoline alkaloidanti-leishmanial activityThe dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine, sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with showed anti-leishmanial activity above 0.1 mg/mL and 75µg/mL (inhibited 50% promastigote growth), respectively.Instituto de Tecnologia do Paraná - Tecpar2011-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100008Brazilian Archives of Biology and Technology v.54 n.1 2011reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132011000100008info:eu-repo/semantics/openAccessCortez,Lucia Elaine RanieriFerreira,Izabel Cristina PilotoLonardoni,Valdrinez CampanaFerreira,Antonio GilbertoVieira,Paulo CesarSilva,Maria Fátima das Graças Fernandes daFernandes,João BatistaCortez,Diógenes Aparicio Garciaeng2011-03-03T00:00:00Zoai:scielo:S1516-89132011000100008Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2011-03-03T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
title Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
spellingShingle Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
Cortez,Lucia Elaine Ranieri
Almeidea coerulea
Rutaceae
indolopyridoquinazoline alkaloid
anti-leishmanial activity
title_short Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
title_full Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
title_fullStr Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
title_full_unstemmed Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
title_sort Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
author Cortez,Lucia Elaine Ranieri
author_facet Cortez,Lucia Elaine Ranieri
Ferreira,Izabel Cristina Piloto
Lonardoni,Valdrinez Campana
Ferreira,Antonio Gilberto
Vieira,Paulo Cesar
Silva,Maria Fátima das Graças Fernandes da
Fernandes,João Batista
Cortez,Diógenes Aparicio Garcia
author_role author
author2 Ferreira,Izabel Cristina Piloto
Lonardoni,Valdrinez Campana
Ferreira,Antonio Gilberto
Vieira,Paulo Cesar
Silva,Maria Fátima das Graças Fernandes da
Fernandes,João Batista
Cortez,Diógenes Aparicio Garcia
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cortez,Lucia Elaine Ranieri
Ferreira,Izabel Cristina Piloto
Lonardoni,Valdrinez Campana
Ferreira,Antonio Gilberto
Vieira,Paulo Cesar
Silva,Maria Fátima das Graças Fernandes da
Fernandes,João Batista
Cortez,Diógenes Aparicio Garcia
dc.subject.por.fl_str_mv Almeidea coerulea
Rutaceae
indolopyridoquinazoline alkaloid
anti-leishmanial activity
topic Almeidea coerulea
Rutaceae
indolopyridoquinazoline alkaloid
anti-leishmanial activity
description The dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine, sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with showed anti-leishmanial activity above 0.1 mg/mL and 75µg/mL (inhibited 50% promastigote growth), respectively.
publishDate 2011
dc.date.none.fl_str_mv 2011-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132011000100008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.54 n.1 2011
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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