Insecticide distribution model in human tissues viewing worker's health monitoring programs
Autor(a) principal: | |
---|---|
Data de Publicação: | 2009 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000400011 |
Resumo: | This work aimed at evaluating the characteristics of thirty nine insecticides on tissue distribution and accumulation, using their physico-chemical characteristics and the tissues lipid contents to calculate the compounds distribution among the tissues. The insecticides evaluated were selected among those registered in Brazil for agriculture use. The level I fugacity model was used for the calculations of insecticide distribution among the tissues of muscles, viscera, skin, fat, blood, liver, kidneys and gut. The octanol-water partition coefficient, water solubility and tissue lipid contents showed an insecticide distribution in human tissues. Cluster analysis was performed aiming the identification and separation of insecticides groups based on their physico-chemical characteristics as compounds with similar distribution within tissues and at the same time tissues with similar distribution of various insecticides. Cluster analysis pointed out three insecticide groups: in the first, 70 - 86% of insecticide accumulation was found in lipid tissues; in the second, 44 - 58%; and in the third, 9 -19%. These results could contribute to health monitoring programs of farmworkers. |
id |
TECPAR-1_999bd393f7f8fa7105da4fcf08b6b16c |
---|---|
oai_identifier_str |
oai:scielo:S1516-89132009000400011 |
network_acronym_str |
TECPAR-1 |
network_name_str |
Brazilian Archives of Biology and Technology |
repository_id_str |
|
spelling |
Insecticide distribution model in human tissues viewing worker's health monitoring programsFugacity modelInsecticide tissue distributionFarmworkersHealth monitoring programsThis work aimed at evaluating the characteristics of thirty nine insecticides on tissue distribution and accumulation, using their physico-chemical characteristics and the tissues lipid contents to calculate the compounds distribution among the tissues. The insecticides evaluated were selected among those registered in Brazil for agriculture use. The level I fugacity model was used for the calculations of insecticide distribution among the tissues of muscles, viscera, skin, fat, blood, liver, kidneys and gut. The octanol-water partition coefficient, water solubility and tissue lipid contents showed an insecticide distribution in human tissues. Cluster analysis was performed aiming the identification and separation of insecticides groups based on their physico-chemical characteristics as compounds with similar distribution within tissues and at the same time tissues with similar distribution of various insecticides. Cluster analysis pointed out three insecticide groups: in the first, 70 - 86% of insecticide accumulation was found in lipid tissues; in the second, 44 - 58%; and in the third, 9 -19%. These results could contribute to health monitoring programs of farmworkers.Instituto de Tecnologia do Paraná - Tecpar2009-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000400011Brazilian Archives of Biology and Technology v.52 n.4 2009reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132009000400011info:eu-repo/semantics/openAccessParaíba,Lourival CostaCastro,Vera Lúcia Scherholz Salgado deMaia,Aline de Holanda Nuneseng2009-09-10T00:00:00Zoai:scielo:S1516-89132009000400011Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2009-09-10T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Insecticide distribution model in human tissues viewing worker's health monitoring programs |
title |
Insecticide distribution model in human tissues viewing worker's health monitoring programs |
spellingShingle |
Insecticide distribution model in human tissues viewing worker's health monitoring programs Paraíba,Lourival Costa Fugacity model Insecticide tissue distribution Farmworkers Health monitoring programs |
title_short |
Insecticide distribution model in human tissues viewing worker's health monitoring programs |
title_full |
Insecticide distribution model in human tissues viewing worker's health monitoring programs |
title_fullStr |
Insecticide distribution model in human tissues viewing worker's health monitoring programs |
title_full_unstemmed |
Insecticide distribution model in human tissues viewing worker's health monitoring programs |
title_sort |
Insecticide distribution model in human tissues viewing worker's health monitoring programs |
author |
Paraíba,Lourival Costa |
author_facet |
Paraíba,Lourival Costa Castro,Vera Lúcia Scherholz Salgado de Maia,Aline de Holanda Nunes |
author_role |
author |
author2 |
Castro,Vera Lúcia Scherholz Salgado de Maia,Aline de Holanda Nunes |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Paraíba,Lourival Costa Castro,Vera Lúcia Scherholz Salgado de Maia,Aline de Holanda Nunes |
dc.subject.por.fl_str_mv |
Fugacity model Insecticide tissue distribution Farmworkers Health monitoring programs |
topic |
Fugacity model Insecticide tissue distribution Farmworkers Health monitoring programs |
description |
This work aimed at evaluating the characteristics of thirty nine insecticides on tissue distribution and accumulation, using their physico-chemical characteristics and the tissues lipid contents to calculate the compounds distribution among the tissues. The insecticides evaluated were selected among those registered in Brazil for agriculture use. The level I fugacity model was used for the calculations of insecticide distribution among the tissues of muscles, viscera, skin, fat, blood, liver, kidneys and gut. The octanol-water partition coefficient, water solubility and tissue lipid contents showed an insecticide distribution in human tissues. Cluster analysis was performed aiming the identification and separation of insecticides groups based on their physico-chemical characteristics as compounds with similar distribution within tissues and at the same time tissues with similar distribution of various insecticides. Cluster analysis pointed out three insecticide groups: in the first, 70 - 86% of insecticide accumulation was found in lipid tissues; in the second, 44 - 58%; and in the third, 9 -19%. These results could contribute to health monitoring programs of farmworkers. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000400011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000400011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132009000400011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.52 n.4 2009 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318273137737728 |