Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women

Detalhes bibliográficos
Autor(a) principal: Araújo,Karine Lourenzone
Data de Publicação: 2011
Outros Autores: Rezende,Lucas Cunha Dias de, Souza,Letícia Soncini, Daltoé,Renata Dalmaschio, Madeira,Klesia Pirola, Paes,Marcela Ferreira, Herkenhoff,Fernando Luiz, Rangel,Letícia Batista Azevedo, Silva,Ian Victor
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600010
Resumo: The aim of this work was to study the estrogen receptor alpha (ERS1) PvuII and XbaI gene polymorphisms prevalence in randomly selected women population from Rio de Janeiro and Espírito Santo states in Brazil by polymerase chain reaction restriction fragment lengths polymorphism (PCR_RFLP) methodology. It was shown that Rio de Janeiro women exhibited a significantly different prevalence of XbaI polymorphism comparing to Espirito Santo women. Nonetheless, similar prevalence of PvuII polymorphism was found in both women´s populations. Moreover, a strong linkage disequilibrium was observed between these SNPs reinforcing the hypothesis of differential pattern of inheritance observed on such populations.
id TECPAR-1_a1f8a8196866562883fc29c704edda4c
oai_identifier_str oai:scielo:S1516-89132011000600010
network_acronym_str TECPAR-1
network_name_str Brazilian Archives of Biology and Technology
repository_id_str
spelling Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian womenPolymorphismEstrogen ReceptorBrazilian WomenPrevalenceLinkage disequilibriumThe aim of this work was to study the estrogen receptor alpha (ERS1) PvuII and XbaI gene polymorphisms prevalence in randomly selected women population from Rio de Janeiro and Espírito Santo states in Brazil by polymerase chain reaction restriction fragment lengths polymorphism (PCR_RFLP) methodology. It was shown that Rio de Janeiro women exhibited a significantly different prevalence of XbaI polymorphism comparing to Espirito Santo women. Nonetheless, similar prevalence of PvuII polymorphism was found in both women´s populations. Moreover, a strong linkage disequilibrium was observed between these SNPs reinforcing the hypothesis of differential pattern of inheritance observed on such populations.Instituto de Tecnologia do Paraná - Tecpar2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600010Brazilian Archives of Biology and Technology v.54 n.6 2011reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132011000600010info:eu-repo/semantics/openAccessAraújo,Karine LourenzoneRezende,Lucas Cunha Dias deSouza,Letícia SonciniDaltoé,Renata DalmaschioMadeira,Klesia PirolaPaes,Marcela FerreiraHerkenhoff,Fernando LuizRangel,Letícia Batista AzevedoSilva,Ian Victoreng2011-12-13T00:00:00Zoai:scielo:S1516-89132011000600010Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2011-12-13T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
title Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
spellingShingle Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
Araújo,Karine Lourenzone
Polymorphism
Estrogen Receptor
Brazilian Women
Prevalence
Linkage disequilibrium
title_short Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
title_full Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
title_fullStr Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
title_full_unstemmed Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
title_sort Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
author Araújo,Karine Lourenzone
author_facet Araújo,Karine Lourenzone
Rezende,Lucas Cunha Dias de
Souza,Letícia Soncini
Daltoé,Renata Dalmaschio
Madeira,Klesia Pirola
Paes,Marcela Ferreira
Herkenhoff,Fernando Luiz
Rangel,Letícia Batista Azevedo
Silva,Ian Victor
author_role author
author2 Rezende,Lucas Cunha Dias de
Souza,Letícia Soncini
Daltoé,Renata Dalmaschio
Madeira,Klesia Pirola
Paes,Marcela Ferreira
Herkenhoff,Fernando Luiz
Rangel,Letícia Batista Azevedo
Silva,Ian Victor
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Araújo,Karine Lourenzone
Rezende,Lucas Cunha Dias de
Souza,Letícia Soncini
Daltoé,Renata Dalmaschio
Madeira,Klesia Pirola
Paes,Marcela Ferreira
Herkenhoff,Fernando Luiz
Rangel,Letícia Batista Azevedo
Silva,Ian Victor
dc.subject.por.fl_str_mv Polymorphism
Estrogen Receptor
Brazilian Women
Prevalence
Linkage disequilibrium
topic Polymorphism
Estrogen Receptor
Brazilian Women
Prevalence
Linkage disequilibrium
description The aim of this work was to study the estrogen receptor alpha (ERS1) PvuII and XbaI gene polymorphisms prevalence in randomly selected women population from Rio de Janeiro and Espírito Santo states in Brazil by polymerase chain reaction restriction fragment lengths polymorphism (PCR_RFLP) methodology. It was shown that Rio de Janeiro women exhibited a significantly different prevalence of XbaI polymorphism comparing to Espirito Santo women. Nonetheless, similar prevalence of PvuII polymorphism was found in both women´s populations. Moreover, a strong linkage disequilibrium was observed between these SNPs reinforcing the hypothesis of differential pattern of inheritance observed on such populations.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132011000600010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.54 n.6 2011
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
_version_ 1750318274863693824

Registros relacionados