Composition and significance of glycosaminoglycans in the uterus and placenta of mammals
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400512 |
Resumo: | Glycosaminoglycans (GAGs) are heteropolysaccharides in mammalian tissue and consist of repeated disaccharide units with mono-sulfated or non-sulfated monosaccharides. GAGs are important components of the Extracellular Matrix (ECM) with several physiological roles, in the recognition, migration, adhesion, proliferation and differentiation processes. They are also important in angiogenesis, blood homeostasis, immune reactions, follicule development and also in the development of pathologies such as infertility, tumors and metastases. It has been shown that the profile of glycosaminoglycans in the uterine and placental tissues is highly variable throughout the reproductive cycle and during pregnancy. It may be directly related to their physiological or pathological functions in the tissue. The latter has recently triggered special clinical interest. Current review collaborates for a deeper knowledge on the profile and importance of GAGs in uterine and placental tissues throughout the reproductive cycle and pregnancy. It also covers information on the involvement of these molecules in pathological processes. |
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Composition and significance of glycosaminoglycans in the uterus and placenta of mammalsExtracellular matrixhormonal fluctuationreproductive eventseuterium mammalspathologyGlycosaminoglycans (GAGs) are heteropolysaccharides in mammalian tissue and consist of repeated disaccharide units with mono-sulfated or non-sulfated monosaccharides. GAGs are important components of the Extracellular Matrix (ECM) with several physiological roles, in the recognition, migration, adhesion, proliferation and differentiation processes. They are also important in angiogenesis, blood homeostasis, immune reactions, follicule development and also in the development of pathologies such as infertility, tumors and metastases. It has been shown that the profile of glycosaminoglycans in the uterine and placental tissues is highly variable throughout the reproductive cycle and during pregnancy. It may be directly related to their physiological or pathological functions in the tissue. The latter has recently triggered special clinical interest. Current review collaborates for a deeper knowledge on the profile and importance of GAGs in uterine and placental tissues throughout the reproductive cycle and pregnancy. It also covers information on the involvement of these molecules in pathological processes.Instituto de Tecnologia do Paraná - Tecpar2015-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400512Brazilian Archives of Biology and Technology v.58 n.4 2015reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-8913201500281info:eu-repo/semantics/openAccessOliveira,Gleidson Benevides deVale,André Menezes doSantos,Amílton Cesar dosMoura,Carlos Eduardo Bezerra deRocha,Hugo Alexandre de OliveiraOliveira,Moacir Franco deeng2015-10-26T00:00:00Zoai:scielo:S1516-89132015000400512Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2015-10-26T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals |
title |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals |
spellingShingle |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals Oliveira,Gleidson Benevides de Extracellular matrix hormonal fluctuation reproductive events euterium mammals pathology |
title_short |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals |
title_full |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals |
title_fullStr |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals |
title_full_unstemmed |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals |
title_sort |
Composition and significance of glycosaminoglycans in the uterus and placenta of mammals |
author |
Oliveira,Gleidson Benevides de |
author_facet |
Oliveira,Gleidson Benevides de Vale,André Menezes do Santos,Amílton Cesar dos Moura,Carlos Eduardo Bezerra de Rocha,Hugo Alexandre de Oliveira Oliveira,Moacir Franco de |
author_role |
author |
author2 |
Vale,André Menezes do Santos,Amílton Cesar dos Moura,Carlos Eduardo Bezerra de Rocha,Hugo Alexandre de Oliveira Oliveira,Moacir Franco de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira,Gleidson Benevides de Vale,André Menezes do Santos,Amílton Cesar dos Moura,Carlos Eduardo Bezerra de Rocha,Hugo Alexandre de Oliveira Oliveira,Moacir Franco de |
dc.subject.por.fl_str_mv |
Extracellular matrix hormonal fluctuation reproductive events euterium mammals pathology |
topic |
Extracellular matrix hormonal fluctuation reproductive events euterium mammals pathology |
description |
Glycosaminoglycans (GAGs) are heteropolysaccharides in mammalian tissue and consist of repeated disaccharide units with mono-sulfated or non-sulfated monosaccharides. GAGs are important components of the Extracellular Matrix (ECM) with several physiological roles, in the recognition, migration, adhesion, proliferation and differentiation processes. They are also important in angiogenesis, blood homeostasis, immune reactions, follicule development and also in the development of pathologies such as infertility, tumors and metastases. It has been shown that the profile of glycosaminoglycans in the uterine and placental tissues is highly variable throughout the reproductive cycle and during pregnancy. It may be directly related to their physiological or pathological functions in the tissue. The latter has recently triggered special clinical interest. Current review collaborates for a deeper knowledge on the profile and importance of GAGs in uterine and placental tissues throughout the reproductive cycle and pregnancy. It also covers information on the involvement of these molecules in pathological processes. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400512 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400512 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-8913201500281 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.58 n.4 2015 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318277277515776 |