Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals

Detalhes bibliográficos
Autor(a) principal: Braga,Miula Portelinha
Data de Publicação: 2013
Outros Autores: Piovesan,Augusta, Valarini,Natália, Maciel,Sandra Mara, Andrade,Flaviana Bombarda de, Poli-Frederico,Regina Célia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000200009
Resumo: The objective of this study was to analyze the genotypic diversity, frequency of serotypes and the detection of mutacins from Streptococcus mutans isolates in caries-free and caries-active individuals.A total of 260 S. mutans isolated from 28 individuals with and without dental caries were subjected to AP-PCR and PCR screening of glucosyltransferase B, mutacin and serotype genes, which showed the presence of. 70 different genotypes. There was no statistically significant association between the presence of genes for serotypes and mutacins with dental caries. However, there was a statistically significant and a strong association between the higher genotypic diversity in the subjects with caries (r = 0.72, p = 0.001). There was an increase in the number of genotypes with increasing age (p <0.01).
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spelling Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individualsDental cariesgenotypic diversitymutacinserotypeStreptococcus mutansThe objective of this study was to analyze the genotypic diversity, frequency of serotypes and the detection of mutacins from Streptococcus mutans isolates in caries-free and caries-active individuals.A total of 260 S. mutans isolated from 28 individuals with and without dental caries were subjected to AP-PCR and PCR screening of glucosyltransferase B, mutacin and serotype genes, which showed the presence of. 70 different genotypes. There was no statistically significant association between the presence of genes for serotypes and mutacins with dental caries. However, there was a statistically significant and a strong association between the higher genotypic diversity in the subjects with caries (r = 0.72, p = 0.001). There was an increase in the number of genotypes with increasing age (p <0.01).Instituto de Tecnologia do Paraná - Tecpar2013-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000200009Brazilian Archives of Biology and Technology v.56 n.2 2013reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132013000200009info:eu-repo/semantics/openAccessBraga,Miula PortelinhaPiovesan,AugustaValarini,NatáliaMaciel,Sandra MaraAndrade,Flaviana Bombarda dePoli-Frederico,Regina Céliaeng2013-05-24T00:00:00Zoai:scielo:S1516-89132013000200009Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2013-05-24T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
title Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
spellingShingle Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
Braga,Miula Portelinha
Dental caries
genotypic diversity
mutacin
serotype
Streptococcus mutans
title_short Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
title_full Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
title_fullStr Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
title_full_unstemmed Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
title_sort Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
author Braga,Miula Portelinha
author_facet Braga,Miula Portelinha
Piovesan,Augusta
Valarini,Natália
Maciel,Sandra Mara
Andrade,Flaviana Bombarda de
Poli-Frederico,Regina Célia
author_role author
author2 Piovesan,Augusta
Valarini,Natália
Maciel,Sandra Mara
Andrade,Flaviana Bombarda de
Poli-Frederico,Regina Célia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Braga,Miula Portelinha
Piovesan,Augusta
Valarini,Natália
Maciel,Sandra Mara
Andrade,Flaviana Bombarda de
Poli-Frederico,Regina Célia
dc.subject.por.fl_str_mv Dental caries
genotypic diversity
mutacin
serotype
Streptococcus mutans
topic Dental caries
genotypic diversity
mutacin
serotype
Streptococcus mutans
description The objective of this study was to analyze the genotypic diversity, frequency of serotypes and the detection of mutacins from Streptococcus mutans isolates in caries-free and caries-active individuals.A total of 260 S. mutans isolated from 28 individuals with and without dental caries were subjected to AP-PCR and PCR screening of glucosyltransferase B, mutacin and serotype genes, which showed the presence of. 70 different genotypes. There was no statistically significant association between the presence of genes for serotypes and mutacins with dental caries. However, there was a statistically significant and a strong association between the higher genotypic diversity in the subjects with caries (r = 0.72, p = 0.001). There was an increase in the number of genotypes with increasing age (p <0.01).
publishDate 2013
dc.date.none.fl_str_mv 2013-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000200009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000200009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132013000200009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.56 n.2 2013
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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