Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5

Detalhes bibliográficos
Autor(a) principal: Lisbôa,Júlio Augusto Naylor
Data de Publicação: 2009
Outros Autores: Isernhagen,Allan Jürgen, Borges,Alexandre Secorun, Amorim,Rogério Martins, Balarin,Mara Regina Stipp, Lunardi,Michele, Alfieri,Amauri Alcindo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010
Resumo: Bovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis.
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spelling Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5bovinemeningoencephalitisherpesvirusescomplete blood countcerebrospinal fluiddiagnosisBovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis.Instituto de Tecnologia do Paraná - Tecpar2009-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010Brazilian Archives of Biology and Technology v.52 n.spe 2009reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132009000700010info:eu-repo/semantics/openAccessLisbôa,Júlio Augusto NaylorIsernhagen,Allan JürgenBorges,Alexandre SecorunAmorim,Rogério MartinsBalarin,Mara Regina StippLunardi,MicheleAlfieri,Amauri Alcindoeng2010-02-08T00:00:00Zoai:scielo:S1516-89132009000700010Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2010-02-08T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
title Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
spellingShingle Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
Lisbôa,Júlio Augusto Naylor
bovine
meningoencephalitis
herpesviruses
complete blood count
cerebrospinal fluid
diagnosis
title_short Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
title_full Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
title_fullStr Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
title_full_unstemmed Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
title_sort Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
author Lisbôa,Júlio Augusto Naylor
author_facet Lisbôa,Júlio Augusto Naylor
Isernhagen,Allan Jürgen
Borges,Alexandre Secorun
Amorim,Rogério Martins
Balarin,Mara Regina Stipp
Lunardi,Michele
Alfieri,Amauri Alcindo
author_role author
author2 Isernhagen,Allan Jürgen
Borges,Alexandre Secorun
Amorim,Rogério Martins
Balarin,Mara Regina Stipp
Lunardi,Michele
Alfieri,Amauri Alcindo
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lisbôa,Júlio Augusto Naylor
Isernhagen,Allan Jürgen
Borges,Alexandre Secorun
Amorim,Rogério Martins
Balarin,Mara Regina Stipp
Lunardi,Michele
Alfieri,Amauri Alcindo
dc.subject.por.fl_str_mv bovine
meningoencephalitis
herpesviruses
complete blood count
cerebrospinal fluid
diagnosis
topic bovine
meningoencephalitis
herpesviruses
complete blood count
cerebrospinal fluid
diagnosis
description Bovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis.
publishDate 2009
dc.date.none.fl_str_mv 2009-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132009000700010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.52 n.spe 2009
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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