Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010 |
Resumo: | Bovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis. |
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Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5bovinemeningoencephalitisherpesvirusescomplete blood countcerebrospinal fluiddiagnosisBovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis.Instituto de Tecnologia do Paraná - Tecpar2009-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010Brazilian Archives of Biology and Technology v.52 n.spe 2009reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132009000700010info:eu-repo/semantics/openAccessLisbôa,Júlio Augusto NaylorIsernhagen,Allan JürgenBorges,Alexandre SecorunAmorim,Rogério MartinsBalarin,Mara Regina StippLunardi,MicheleAlfieri,Amauri Alcindoeng2010-02-08T00:00:00Zoai:scielo:S1516-89132009000700010Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2010-02-08T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 |
title |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 |
spellingShingle |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 Lisbôa,Júlio Augusto Naylor bovine meningoencephalitis herpesviruses complete blood count cerebrospinal fluid diagnosis |
title_short |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 |
title_full |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 |
title_fullStr |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 |
title_full_unstemmed |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 |
title_sort |
Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5 |
author |
Lisbôa,Júlio Augusto Naylor |
author_facet |
Lisbôa,Júlio Augusto Naylor Isernhagen,Allan Jürgen Borges,Alexandre Secorun Amorim,Rogério Martins Balarin,Mara Regina Stipp Lunardi,Michele Alfieri,Amauri Alcindo |
author_role |
author |
author2 |
Isernhagen,Allan Jürgen Borges,Alexandre Secorun Amorim,Rogério Martins Balarin,Mara Regina Stipp Lunardi,Michele Alfieri,Amauri Alcindo |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Lisbôa,Júlio Augusto Naylor Isernhagen,Allan Jürgen Borges,Alexandre Secorun Amorim,Rogério Martins Balarin,Mara Regina Stipp Lunardi,Michele Alfieri,Amauri Alcindo |
dc.subject.por.fl_str_mv |
bovine meningoencephalitis herpesviruses complete blood count cerebrospinal fluid diagnosis |
topic |
bovine meningoencephalitis herpesviruses complete blood count cerebrospinal fluid diagnosis |
description |
Bovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132009000700010 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.52 n.spe 2009 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318273545633792 |