A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids

Detalhes bibliográficos
Autor(a) principal: Prosdocimi, Francisco
Data de Publicação: 2007
Outros Autores: Mudado, Maurício de Alvarenga, Ortega, José Miguel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UCB
Texto Completo: http://twingo.ucb.br:8080/jspui/handle/10869/663
https://repositorio.ucb.br:9443/jspui/handle/123456789/7912
Resumo: We investigated the hypothesis that essential amino acids are being replaced in proteins by non-essential amino acids.We compared the amino acid composition in human, worm and fly proteomes, organisms that cannot synthesize all amino acids, with the amino acids of the proteomes of plant, bakers yeast and budding yeast, which are capable of synthesizing them. The analysis covered 460,737 proteins (212,197,907 amino acids). The data suggest a bias towards the usage of non-essential amino acids (mostly the set GAPQC) by metazoan organisms, except for the worm, a Pseudocoelomata. Our results support the hypothesis that non-essential amino acids have been substituting essential ones in the Coelomata.
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spelling Prosdocimi, FranciscoMudado, Maurício de AlvarengaOrtega, José Miguel2016-10-10T03:53:04Z2016-10-10T03:53:04Z2007PROSDOCIMI, Francisco; MUDADO, Maurício de Alvarenga; ORTEGA, José Miguel. A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids. Computers in Biology and Medicine, v. 37, p. 159-165, 2007.http://twingo.ucb.br:8080/jspui/handle/10869/663https://repositorio.ucb.br:9443/jspui/handle/123456789/7912We investigated the hypothesis that essential amino acids are being replaced in proteins by non-essential amino acids.We compared the amino acid composition in human, worm and fly proteomes, organisms that cannot synthesize all amino acids, with the amino acids of the proteomes of plant, bakers yeast and budding yeast, which are capable of synthesizing them. The analysis covered 460,737 proteins (212,197,907 amino acids). The data suggest a bias towards the usage of non-essential amino acids (mostly the set GAPQC) by metazoan organisms, except for the worm, a Pseudocoelomata. Our results support the hypothesis that non-essential amino acids have been substituting essential ones in the Coelomata.Made available in DSpace on 2016-10-10T03:53:04Z (GMT). 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dc.title.pt_BR.fl_str_mv A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
title A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
spellingShingle A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
Prosdocimi, Francisco
Diet
Genome
Proteome
Essential amino acids
Metazoa
Amino acid usage
title_short A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
title_full A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
title_fullStr A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
title_full_unstemmed A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
title_sort A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids
author Prosdocimi, Francisco
author_facet Prosdocimi, Francisco
Mudado, Maurício de Alvarenga
Ortega, José Miguel
author_role author
author2 Mudado, Maurício de Alvarenga
Ortega, José Miguel
author2_role author
author
dc.contributor.author.fl_str_mv Prosdocimi, Francisco
Mudado, Maurício de Alvarenga
Ortega, José Miguel
dc.subject.por.fl_str_mv Diet
Genome
Proteome
Essential amino acids
Metazoa
Amino acid usage
topic Diet
Genome
Proteome
Essential amino acids
Metazoa
Amino acid usage
dc.description.abstract.por.fl_txt_mv We investigated the hypothesis that essential amino acids are being replaced in proteins by non-essential amino acids.We compared the amino acid composition in human, worm and fly proteomes, organisms that cannot synthesize all amino acids, with the amino acids of the proteomes of plant, bakers yeast and budding yeast, which are capable of synthesizing them. The analysis covered 460,737 proteins (212,197,907 amino acids). The data suggest a bias towards the usage of non-essential amino acids (mostly the set GAPQC) by metazoan organisms, except for the worm, a Pseudocoelomata. Our results support the hypothesis that non-essential amino acids have been substituting essential ones in the Coelomata.
dc.description.status.pt_BR.fl_txt_mv Publicado
description We investigated the hypothesis that essential amino acids are being replaced in proteins by non-essential amino acids.We compared the amino acid composition in human, worm and fly proteomes, organisms that cannot synthesize all amino acids, with the amino acids of the proteomes of plant, bakers yeast and budding yeast, which are capable of synthesizing them. The analysis covered 460,737 proteins (212,197,907 amino acids). The data suggest a bias towards the usage of non-essential amino acids (mostly the set GAPQC) by metazoan organisms, except for the worm, a Pseudocoelomata. Our results support the hypothesis that non-essential amino acids have been substituting essential ones in the Coelomata.
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2016-10-10T03:53:04Z
dc.date.available.fl_str_mv 2016-10-10T03:53:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
status_str publishedVersion
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dc.identifier.citation.fl_str_mv PROSDOCIMI, Francisco; MUDADO, Maurício de Alvarenga; ORTEGA, José Miguel. A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids. Computers in Biology and Medicine, v. 37, p. 159-165, 2007.
dc.identifier.uri.fl_str_mv http://twingo.ucb.br:8080/jspui/handle/10869/663
https://repositorio.ucb.br:9443/jspui/handle/123456789/7912
identifier_str_mv PROSDOCIMI, Francisco; MUDADO, Maurício de Alvarenga; ORTEGA, José Miguel. A set of amino acids found to occur more frequently in human and fly than in plant and yeast proteomes consists of non-essential amino acids. Computers in Biology and Medicine, v. 37, p. 159-165, 2007.
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