Connective tissue responses to calcium hydroxide-based root canal medicaments
Autor(a) principal: | |
---|---|
Data de Publicação: | 1999 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UCB |
Texto Completo: | http://hdl.handle.net/123456789/205 https://repositorio.ucb.br:9443/jspui/handle/123456789/7432 |
Resumo: | Aim The objective of the present study was to evaluate the tissue inflammatory response induced by calcium hydroxide pastes, with or without paramonochlorophenol and camphor. Methodology Isogenic BALB/c mice were inoculated into the subcutaneous tissue with either 0.1 mL of a suspension of Calen, Calen with camphorated paramonochlorophenol, Calen with paramonochlorophenol, Calasept paste or phosphatebuffered saline (control). After 6, 12 and 24 h and 2, 3, 5, 7 and 15 days, three animals in each group were sacrificed and the excised lesions processed for histopathological evaluation of the inflammatory response. Events monitored and graded included the assessment of vascular congestion, oedema, haemorrhage, inflammatory infiltrate, necrosis and tissue repair. Results The pastes induced an inflammatory response at every observation period, although the intensity, duration and extension of inflammation varied. Calen paste always produced an initial shortterm inflammatory response whilst the other pastes produced extended reactions. All pastes allowed repair to take place by the end of the experimental period, although the speed of this process varied between the materials. Calen presented the best biocompatibility; the phenolic compound caused greater tissue response, which was even more severe in the absence of camphor. Calasept paste was damaging and the repair process slower. Conclusions All calcium hydroxide formulations caused an inflammatory response. The severity and longevity of the responses varied between pastes as a result of the various antiseptic agents. Although irritating, repair was apparent with all formulations. |
id |
UCB-2_72fc96a9e90ae6bc7e04672043f81c31 |
---|---|
oai_identifier_str |
oai:200.214.135.189:123456789/7432 |
network_acronym_str |
UCB-2 |
network_name_str |
Repositório Institucional da UCB |
spelling |
Nelson-Filho, PauloSilva, Lea Assed BezerraLeonardo, Mario RobertoUtrilla, Lidia SabbagCavalcanti Neto, Florêncio Figueiredo2016-10-10T03:51:28Z2016-10-10T03:51:28Z1999NELSON FILHO, Paulo at al. Connective tissue responses to calcium hydroxide-based root canal medicaments. International Endodontic Journal, Estados Unidos, v. 32, p. 303-311, 1999.http://hdl.handle.net/123456789/205https://repositorio.ucb.br:9443/jspui/handle/123456789/7432Aim The objective of the present study was to evaluate the tissue inflammatory response induced by calcium hydroxide pastes, with or without paramonochlorophenol and camphor. Methodology Isogenic BALB/c mice were inoculated into the subcutaneous tissue with either 0.1 mL of a suspension of Calen, Calen with camphorated paramonochlorophenol, Calen with paramonochlorophenol, Calasept paste or phosphatebuffered saline (control). After 6, 12 and 24 h and 2, 3, 5, 7 and 15 days, three animals in each group were sacrificed and the excised lesions processed for histopathological evaluation of the inflammatory response. Events monitored and graded included the assessment of vascular congestion, oedema, haemorrhage, inflammatory infiltrate, necrosis and tissue repair. Results The pastes induced an inflammatory response at every observation period, although the intensity, duration and extension of inflammation varied. Calen paste always produced an initial shortterm inflammatory response whilst the other pastes produced extended reactions. All pastes allowed repair to take place by the end of the experimental period, although the speed of this process varied between the materials. Calen presented the best biocompatibility; the phenolic compound caused greater tissue response, which was even more severe in the absence of camphor. Calasept paste was damaging and the repair process slower. Conclusions All calcium hydroxide formulations caused an inflammatory response. The severity and longevity of the responses varied between pastes as a result of the various antiseptic agents. Although irritating, repair was apparent with all formulations.Made available in DSpace on 2016-10-10T03:51:28Z (GMT). No. of bitstreams: 5 Connective tissue responses to calcium hydroxide_based root canal medicaments.pdf: 449193 bytes, checksum: 2259bfc4d732d861f10b9fd6654de5fe (MD5) license_url: 52 bytes, checksum: 2f32edb9c19a57e928372a33fd08dba5 (MD5) license_text: 22213 bytes, checksum: a03e546c827bdf47d4a06cfce5c2fb1d (MD5) license_rdf: 23692 bytes, checksum: 13c15f5d379f2fc75f816604d123f74e (MD5) license.txt: 1818 bytes, checksum: 46de3043f08e87659ae535ef74b8ce9d (MD5) Previous issue date: 1999SimPublicadoTextoAntibacterial dressingBiocompatibilityCalcium hydroxideConnective tissue responses to calcium hydroxide-based root canal medicamentsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInternational Endodontic Journalhttp://onlinelibrary.wiley.com/doi/10.1046/j.1365-2591.1999.00225.x/pdfinfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UCBinstname:Universidade Católica de Brasília (UCB)instacron:UCBORIGINALConnective tissue responses to calcium hydroxide_based root canal medicaments.pdfapplication/pdf449193https://200.214.135.178:9443/jspui/bitstream/123456789/7432/1/Connective%20tissue%20responses%20to%20calcium%20hydroxide_based%20root%20canal%20medicaments.pdf2259bfc4d732d861f10b9fd6654de5feMD51CC-LICENSElicense_urlapplication/octet-stream52https://200.214.135.178:9443/jspui/bitstream/123456789/7432/2/license_url2f32edb9c19a57e928372a33fd08dba5MD52license_textapplication/octet-stream22213https://200.214.135.178:9443/jspui/bitstream/123456789/7432/3/license_texta03e546c827bdf47d4a06cfce5c2fb1dMD53license_rdfapplication/octet-stream23692https://200.214.135.178:9443/jspui/bitstream/123456789/7432/4/license_rdf13c15f5d379f2fc75f816604d123f74eMD54LICENSElicense.txttext/plain1818https://200.214.135.178:9443/jspui/bitstream/123456789/7432/5/license.txt46de3043f08e87659ae535ef74b8ce9dMD55TEXTConnective tissue responses to calcium hydroxide_based root canal medicaments.pdf.txtConnective tissue responses to calcium hydroxide_based root canal medicaments.pdf.txtExtracted texttext/plain27531https://200.214.135.178:9443/jspui/bitstream/123456789/7432/6/Connective%20tissue%20responses%20to%20calcium%20hydroxide_based%20root%20canal%20medicaments.pdf.txt0ba2a3c9528c96d6b97d8c127ff50d82MD56123456789/74322017-01-17 14:56:51.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ório de Publicaçõeshttps://repositorio.ucb.br:9443/jspui/ |
dc.title.pt_BR.fl_str_mv |
Connective tissue responses to calcium hydroxide-based root canal medicaments |
title |
Connective tissue responses to calcium hydroxide-based root canal medicaments |
spellingShingle |
Connective tissue responses to calcium hydroxide-based root canal medicaments Nelson-Filho, Paulo Antibacterial dressing Biocompatibility Calcium hydroxide |
title_short |
Connective tissue responses to calcium hydroxide-based root canal medicaments |
title_full |
Connective tissue responses to calcium hydroxide-based root canal medicaments |
title_fullStr |
Connective tissue responses to calcium hydroxide-based root canal medicaments |
title_full_unstemmed |
Connective tissue responses to calcium hydroxide-based root canal medicaments |
title_sort |
Connective tissue responses to calcium hydroxide-based root canal medicaments |
author |
Nelson-Filho, Paulo |
author_facet |
Nelson-Filho, Paulo Silva, Lea Assed Bezerra Leonardo, Mario Roberto Utrilla, Lidia Sabbag Cavalcanti Neto, Florêncio Figueiredo |
author_role |
author |
author2 |
Silva, Lea Assed Bezerra Leonardo, Mario Roberto Utrilla, Lidia Sabbag Cavalcanti Neto, Florêncio Figueiredo |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Nelson-Filho, Paulo Silva, Lea Assed Bezerra Leonardo, Mario Roberto Utrilla, Lidia Sabbag Cavalcanti Neto, Florêncio Figueiredo |
dc.subject.por.fl_str_mv |
Antibacterial dressing Biocompatibility Calcium hydroxide |
topic |
Antibacterial dressing Biocompatibility Calcium hydroxide |
dc.description.abstract.por.fl_txt_mv |
Aim The objective of the present study was to evaluate the tissue inflammatory response induced by calcium hydroxide pastes, with or without paramonochlorophenol and camphor. Methodology Isogenic BALB/c mice were inoculated into the subcutaneous tissue with either 0.1 mL of a suspension of Calen, Calen with camphorated paramonochlorophenol, Calen with paramonochlorophenol, Calasept paste or phosphatebuffered saline (control). After 6, 12 and 24 h and 2, 3, 5, 7 and 15 days, three animals in each group were sacrificed and the excised lesions processed for histopathological evaluation of the inflammatory response. Events monitored and graded included the assessment of vascular congestion, oedema, haemorrhage, inflammatory infiltrate, necrosis and tissue repair. Results The pastes induced an inflammatory response at every observation period, although the intensity, duration and extension of inflammation varied. Calen paste always produced an initial shortterm inflammatory response whilst the other pastes produced extended reactions. All pastes allowed repair to take place by the end of the experimental period, although the speed of this process varied between the materials. Calen presented the best biocompatibility; the phenolic compound caused greater tissue response, which was even more severe in the absence of camphor. Calasept paste was damaging and the repair process slower. Conclusions All calcium hydroxide formulations caused an inflammatory response. The severity and longevity of the responses varied between pastes as a result of the various antiseptic agents. Although irritating, repair was apparent with all formulations. |
dc.description.version.pt_BR.fl_txt_mv |
Sim |
dc.description.status.pt_BR.fl_txt_mv |
Publicado |
description |
Aim The objective of the present study was to evaluate the tissue inflammatory response induced by calcium hydroxide pastes, with or without paramonochlorophenol and camphor. Methodology Isogenic BALB/c mice were inoculated into the subcutaneous tissue with either 0.1 mL of a suspension of Calen, Calen with camphorated paramonochlorophenol, Calen with paramonochlorophenol, Calasept paste or phosphatebuffered saline (control). After 6, 12 and 24 h and 2, 3, 5, 7 and 15 days, three animals in each group were sacrificed and the excised lesions processed for histopathological evaluation of the inflammatory response. Events monitored and graded included the assessment of vascular congestion, oedema, haemorrhage, inflammatory infiltrate, necrosis and tissue repair. Results The pastes induced an inflammatory response at every observation period, although the intensity, duration and extension of inflammation varied. Calen paste always produced an initial shortterm inflammatory response whilst the other pastes produced extended reactions. All pastes allowed repair to take place by the end of the experimental period, although the speed of this process varied between the materials. Calen presented the best biocompatibility; the phenolic compound caused greater tissue response, which was even more severe in the absence of camphor. Calasept paste was damaging and the repair process slower. Conclusions All calcium hydroxide formulations caused an inflammatory response. The severity and longevity of the responses varied between pastes as a result of the various antiseptic agents. Although irritating, repair was apparent with all formulations. |
publishDate |
1999 |
dc.date.issued.fl_str_mv |
1999 |
dc.date.accessioned.fl_str_mv |
2016-10-10T03:51:28Z |
dc.date.available.fl_str_mv |
2016-10-10T03:51:28Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
status_str |
publishedVersion |
format |
article |
dc.identifier.citation.fl_str_mv |
NELSON FILHO, Paulo at al. Connective tissue responses to calcium hydroxide-based root canal medicaments. International Endodontic Journal, Estados Unidos, v. 32, p. 303-311, 1999. |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/123456789/205 https://repositorio.ucb.br:9443/jspui/handle/123456789/7432 |
identifier_str_mv |
NELSON FILHO, Paulo at al. Connective tissue responses to calcium hydroxide-based root canal medicaments. International Endodontic Journal, Estados Unidos, v. 32, p. 303-311, 1999. |
url |
http://hdl.handle.net/123456789/205 https://repositorio.ucb.br:9443/jspui/handle/123456789/7432 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.publisherversion.pt_BR.fl_str_mv |
http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2591.1999.00225.x/pdf |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
Texto |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UCB instname:Universidade Católica de Brasília (UCB) instacron:UCB |
instname_str |
Universidade Católica de Brasília (UCB) |
instacron_str |
UCB |
institution |
UCB |
reponame_str |
Repositório Institucional da UCB |
collection |
Repositório Institucional da UCB |
bitstream.url.fl_str_mv |
https://200.214.135.178:9443/jspui/bitstream/123456789/7432/1/Connective%20tissue%20responses%20to%20calcium%20hydroxide_based%20root%20canal%20medicaments.pdf https://200.214.135.178:9443/jspui/bitstream/123456789/7432/2/license_url https://200.214.135.178:9443/jspui/bitstream/123456789/7432/3/license_text https://200.214.135.178:9443/jspui/bitstream/123456789/7432/4/license_rdf https://200.214.135.178:9443/jspui/bitstream/123456789/7432/5/license.txt https://200.214.135.178:9443/jspui/bitstream/123456789/7432/6/Connective%20tissue%20responses%20to%20calcium%20hydroxide_based%20root%20canal%20medicaments.pdf.txt |
bitstream.checksum.fl_str_mv |
2259bfc4d732d861f10b9fd6654de5fe 2f32edb9c19a57e928372a33fd08dba5 a03e546c827bdf47d4a06cfce5c2fb1d 13c15f5d379f2fc75f816604d123f74e 46de3043f08e87659ae535ef74b8ce9d 0ba2a3c9528c96d6b97d8c127ff50d82 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1724829827756720128 |