Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection
Autor(a) principal: | |
---|---|
Data de Publicação: | 2002 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UCB |
Texto Completo: | http://twingo.ucb.br:8080/jspui/handle/10869/538 https://repositorio.ucb.br:9443/jspui/handle/123456789/7654 |
Resumo: | Insect pests and pathogens (fungi, bacteria and viruses) are responsible for severe crop losses. Insects feed directly on the plant tissues, while the pathogens lead to damage or death of the plant. Plants have evolved a certain degree of resistance through the production of defence compounds, which may be aproteic, e.g. antibiotics, alkaloids, terpenes, cyanogenic glucosides or proteic, e.g. chitinases, b-1,3-glu- canases, lectins, arcelins, vicilins, systemins and enzyme inhibitors. The enzyme inhibitors impede digestion through their action on insect gut digestive a-amylases and pro- teinases, which play a key role in the digestion of plant starch and proteins. The natural defences of crop plants may be improved through the use of transgenic technology. Current research in the area focuses particularly on weevils as these are highly dependent on starch for their energy supply. Six di€erent a-amylase inhibitor classes, lectin-like, knottin-like, cereal-type, Kunitz-like, c-purothionin-like and thaumatin-like could be used in pest control. These classes of inhibitors show remarkable structural variety leading to di€erent modes of inhibition and di€erent speci®city pro®les against diverse a-amylases. Speci®city of inhibition is an important issue as the introduced inhibitor must not adversely a€ect the plant's own a-amylases, nor the nutritional value of the crop. Of particular interest are some bifunctional inhibitors with additional favourable properties, such as proteinase inhibitory activity or chitin- ase activity. The area has bene®ted from the recent deter- mination of many structures of a-amylases, inhibitors and complexes. These structures highlight the remarkable variety in structural modes of a-amylase inhibition. The continuing discovery of new classes of a-amylase inhibitor ensures that exciting discoveries remain to be made. In this review, we summarize existing knowledge of insect a-am- ylases, plant a-amylase inhibitors and their interaction. Positive results recently obtained for transgenic plants and future prospects in the area are reviewed. |
id |
UCB-2_c7a6a61b7ea114d78da6d0984cbd58ec |
---|---|
oai_identifier_str |
oai:200.214.135.189:123456789/7654 |
network_acronym_str |
UCB-2 |
network_name_str |
Repositório Institucional da UCB |
spelling |
Franco, Octávio L.Rigden, Daniel J.Melo, Francislete R.Grossi-de-Sa, Maria F.2016-10-10T03:52:14Z2016-10-10T03:52:14Z2002FRANCO, Octávio L. Plant a-amylase inhibitors and their interaction with insect a-amylases Structure, function and potential for crop protection. Eur. J. Biochem. v. 269, p. 397- 412, 2002.http://twingo.ucb.br:8080/jspui/handle/10869/538https://repositorio.ucb.br:9443/jspui/handle/123456789/7654Insect pests and pathogens (fungi, bacteria and viruses) are responsible for severe crop losses. Insects feed directly on the plant tissues, while the pathogens lead to damage or death of the plant. Plants have evolved a certain degree of resistance through the production of defence compounds, which may be aproteic, e.g. antibiotics, alkaloids, terpenes, cyanogenic glucosides or proteic, e.g. chitinases, b-1,3-glu- canases, lectins, arcelins, vicilins, systemins and enzyme inhibitors. The enzyme inhibitors impede digestion through their action on insect gut digestive a-amylases and pro- teinases, which play a key role in the digestion of plant starch and proteins. The natural defences of crop plants may be improved through the use of transgenic technology. Current research in the area focuses particularly on weevils as these are highly dependent on starch for their energy supply. Six di€erent a-amylase inhibitor classes, lectin-like, knottin-like, cereal-type, Kunitz-like, c-purothionin-like and thaumatin-like could be used in pest control. These classes of inhibitors show remarkable structural variety leading to di€erent modes of inhibition and di€erent speci®city pro®les against diverse a-amylases. Speci®city of inhibition is an important issue as the introduced inhibitor must not adversely a€ect the plant's own a-amylases, nor the nutritional value of the crop. Of particular interest are some bifunctional inhibitors with additional favourable properties, such as proteinase inhibitory activity or chitin- ase activity. The area has bene®ted from the recent deter- mination of many structures of a-amylases, inhibitors and complexes. These structures highlight the remarkable variety in structural modes of a-amylase inhibition. The continuing discovery of new classes of a-amylase inhibitor ensures that exciting discoveries remain to be made. In this review, we summarize existing knowledge of insect a-am- ylases, plant a-amylase inhibitors and their interaction. Positive results recently obtained for transgenic plants and future prospects in the area are reviewed.Made available in DSpace on 2016-10-10T03:52:14Z (GMT). No. of bitstreams: 5 Plant alpha-amylase inhibitors and their interaction with insect alpha_amylases _ Structureor.pdf: 471609 bytes, checksum: 4349bfe6f6fd3b2b3d08ca0d3e088c5b (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 23851 bytes, checksum: 294cb7010cc40c47642971e073de3dba (MD5) license_rdf: 23892 bytes, checksum: afd5dad10b1d1e6dc10c8c5d25222c7a (MD5) license.txt: 1887 bytes, checksum: 445d1980f282ec865917de35a4c622f6 (MD5) Previous issue date: 2002Federation of european biochemical societiesSimPublicadoTextoRestrito UCBinfo:eu-repo/semantics/openAccessA-Amylase InhibitorKnottin-likeLectin-likeThaumatin-likeKunitzCereal-typeBean weevilBifunctional inhibitorsPlant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleEuropean journal of biochemistryhttp://onlinelibrary.wiley.com/doi/10.1046/j.0014-2956.2001.02656.x/pdfengreponame:Repositório Institucional da UCBinstname:Universidade Católica de Brasília (UCB)instacron:UCBORIGINALPlant alpha-amylase inhibitors and their interaction with insect alpha_amylases _ Structureor.pdfapplication/pdf471609https://200.214.135.178:9443/jspui/bitstream/123456789/7654/1/Plant%20alpha-amylase%20inhibitors%20and%20their%20interaction%20with%20insect%20alpha_amylases%20_%20Structureor.pdf4349bfe6f6fd3b2b3d08ca0d3e088c5bMD51CC-LICENSElicense_urlapplication/octet-stream52https://200.214.135.178:9443/jspui/bitstream/123456789/7654/2/license_url3d480ae6c91e310daba2020f8787d6f9MD52license_textapplication/octet-stream23851https://200.214.135.178:9443/jspui/bitstream/123456789/7654/3/license_text294cb7010cc40c47642971e073de3dbaMD53license_rdfapplication/octet-stream23892https://200.214.135.178:9443/jspui/bitstream/123456789/7654/4/license_rdfafd5dad10b1d1e6dc10c8c5d25222c7aMD54LICENSElicense.txttext/plain1887https://200.214.135.178:9443/jspui/bitstream/123456789/7654/5/license.txt445d1980f282ec865917de35a4c622f6MD55TEXTPlant alpha-amylase inhibitors and their interaction with insect alpha_amylases _ Structureor.pdf.txtPlant alpha-amylase inhibitors and their interaction with insect alpha_amylases _ Structureor.pdf.txtExtracted texttext/plain91888https://200.214.135.178:9443/jspui/bitstream/123456789/7654/6/Plant%20alpha-amylase%20inhibitors%20and%20their%20interaction%20with%20insect%20alpha_amylases%20_%20Structureor.pdf.txt8d954e97b782d41be8c8d123ab1c6fbeMD56123456789/76542017-01-17 15:09:48.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ório de Publicaçõeshttps://repositorio.ucb.br:9443/jspui/ |
dc.title.pt_BR.fl_str_mv |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection |
title |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection |
spellingShingle |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection Franco, Octávio L. A-Amylase Inhibitor Knottin-like Lectin-like Thaumatin-like Kunitz Cereal-type Bean weevil Bifunctional inhibitors |
title_short |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection |
title_full |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection |
title_fullStr |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection |
title_full_unstemmed |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection |
title_sort |
Plant a-amylase inhibitors and their interaction with insect a-amylases structure, function and potential for crop protection |
author |
Franco, Octávio L. |
author_facet |
Franco, Octávio L. Rigden, Daniel J. Melo, Francislete R. Grossi-de-Sa, Maria F. |
author_role |
author |
author2 |
Rigden, Daniel J. Melo, Francislete R. Grossi-de-Sa, Maria F. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Franco, Octávio L. Rigden, Daniel J. Melo, Francislete R. Grossi-de-Sa, Maria F. |
dc.subject.por.fl_str_mv |
A-Amylase Inhibitor Knottin-like Lectin-like Thaumatin-like Kunitz Cereal-type Bean weevil Bifunctional inhibitors |
topic |
A-Amylase Inhibitor Knottin-like Lectin-like Thaumatin-like Kunitz Cereal-type Bean weevil Bifunctional inhibitors |
dc.description.sponsorship.fl_txt_mv |
Federation of european biochemical societies |
dc.description.abstract.por.fl_txt_mv |
Insect pests and pathogens (fungi, bacteria and viruses) are responsible for severe crop losses. Insects feed directly on the plant tissues, while the pathogens lead to damage or death of the plant. Plants have evolved a certain degree of resistance through the production of defence compounds, which may be aproteic, e.g. antibiotics, alkaloids, terpenes, cyanogenic glucosides or proteic, e.g. chitinases, b-1,3-glu- canases, lectins, arcelins, vicilins, systemins and enzyme inhibitors. The enzyme inhibitors impede digestion through their action on insect gut digestive a-amylases and pro- teinases, which play a key role in the digestion of plant starch and proteins. The natural defences of crop plants may be improved through the use of transgenic technology. Current research in the area focuses particularly on weevils as these are highly dependent on starch for their energy supply. Six di€erent a-amylase inhibitor classes, lectin-like, knottin-like, cereal-type, Kunitz-like, c-purothionin-like and thaumatin-like could be used in pest control. These classes of inhibitors show remarkable structural variety leading to di€erent modes of inhibition and di€erent speci®city pro®les against diverse a-amylases. Speci®city of inhibition is an important issue as the introduced inhibitor must not adversely a€ect the plant's own a-amylases, nor the nutritional value of the crop. Of particular interest are some bifunctional inhibitors with additional favourable properties, such as proteinase inhibitory activity or chitin- ase activity. The area has bene®ted from the recent deter- mination of many structures of a-amylases, inhibitors and complexes. These structures highlight the remarkable variety in structural modes of a-amylase inhibition. The continuing discovery of new classes of a-amylase inhibitor ensures that exciting discoveries remain to be made. In this review, we summarize existing knowledge of insect a-am- ylases, plant a-amylase inhibitors and their interaction. Positive results recently obtained for transgenic plants and future prospects in the area are reviewed. |
dc.description.version.pt_BR.fl_txt_mv |
Sim |
dc.description.status.pt_BR.fl_txt_mv |
Publicado |
description |
Insect pests and pathogens (fungi, bacteria and viruses) are responsible for severe crop losses. Insects feed directly on the plant tissues, while the pathogens lead to damage or death of the plant. Plants have evolved a certain degree of resistance through the production of defence compounds, which may be aproteic, e.g. antibiotics, alkaloids, terpenes, cyanogenic glucosides or proteic, e.g. chitinases, b-1,3-glu- canases, lectins, arcelins, vicilins, systemins and enzyme inhibitors. The enzyme inhibitors impede digestion through their action on insect gut digestive a-amylases and pro- teinases, which play a key role in the digestion of plant starch and proteins. The natural defences of crop plants may be improved through the use of transgenic technology. Current research in the area focuses particularly on weevils as these are highly dependent on starch for their energy supply. Six di€erent a-amylase inhibitor classes, lectin-like, knottin-like, cereal-type, Kunitz-like, c-purothionin-like and thaumatin-like could be used in pest control. These classes of inhibitors show remarkable structural variety leading to di€erent modes of inhibition and di€erent speci®city pro®les against diverse a-amylases. Speci®city of inhibition is an important issue as the introduced inhibitor must not adversely a€ect the plant's own a-amylases, nor the nutritional value of the crop. Of particular interest are some bifunctional inhibitors with additional favourable properties, such as proteinase inhibitory activity or chitin- ase activity. The area has bene®ted from the recent deter- mination of many structures of a-amylases, inhibitors and complexes. These structures highlight the remarkable variety in structural modes of a-amylase inhibition. The continuing discovery of new classes of a-amylase inhibitor ensures that exciting discoveries remain to be made. In this review, we summarize existing knowledge of insect a-am- ylases, plant a-amylase inhibitors and their interaction. Positive results recently obtained for transgenic plants and future prospects in the area are reviewed. |
publishDate |
2002 |
dc.date.issued.fl_str_mv |
2002 |
dc.date.accessioned.fl_str_mv |
2016-10-10T03:52:14Z |
dc.date.available.fl_str_mv |
2016-10-10T03:52:14Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
status_str |
publishedVersion |
format |
article |
dc.identifier.citation.fl_str_mv |
FRANCO, Octávio L. Plant a-amylase inhibitors and their interaction with insect a-amylases Structure, function and potential for crop protection. Eur. J. Biochem. v. 269, p. 397- 412, 2002. |
dc.identifier.uri.fl_str_mv |
http://twingo.ucb.br:8080/jspui/handle/10869/538 https://repositorio.ucb.br:9443/jspui/handle/123456789/7654 |
identifier_str_mv |
FRANCO, Octávio L. Plant a-amylase inhibitors and their interaction with insect a-amylases Structure, function and potential for crop protection. Eur. J. Biochem. v. 269, p. 397- 412, 2002. |
url |
http://twingo.ucb.br:8080/jspui/handle/10869/538 https://repositorio.ucb.br:9443/jspui/handle/123456789/7654 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.publisherversion.pt_BR.fl_str_mv |
http://onlinelibrary.wiley.com/doi/10.1046/j.0014-2956.2001.02656.x/pdf |
dc.rights.driver.fl_str_mv |
Restrito UCB info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Restrito UCB |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
Texto |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UCB instname:Universidade Católica de Brasília (UCB) instacron:UCB |
instname_str |
Universidade Católica de Brasília (UCB) |
instacron_str |
UCB |
institution |
UCB |
reponame_str |
Repositório Institucional da UCB |
collection |
Repositório Institucional da UCB |
bitstream.url.fl_str_mv |
https://200.214.135.178:9443/jspui/bitstream/123456789/7654/1/Plant%20alpha-amylase%20inhibitors%20and%20their%20interaction%20with%20insect%20alpha_amylases%20_%20Structureor.pdf https://200.214.135.178:9443/jspui/bitstream/123456789/7654/2/license_url https://200.214.135.178:9443/jspui/bitstream/123456789/7654/3/license_text https://200.214.135.178:9443/jspui/bitstream/123456789/7654/4/license_rdf https://200.214.135.178:9443/jspui/bitstream/123456789/7654/5/license.txt https://200.214.135.178:9443/jspui/bitstream/123456789/7654/6/Plant%20alpha-amylase%20inhibitors%20and%20their%20interaction%20with%20insect%20alpha_amylases%20_%20Structureor.pdf.txt |
bitstream.checksum.fl_str_mv |
4349bfe6f6fd3b2b3d08ca0d3e088c5b 3d480ae6c91e310daba2020f8787d6f9 294cb7010cc40c47642971e073de3dba afd5dad10b1d1e6dc10c8c5d25222c7a 445d1980f282ec865917de35a4c622f6 8d954e97b782d41be8c8d123ab1c6fbe |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1724829829993332736 |