Efeito imunomodulador de leveduras frescas em novilhas confinadas
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações do UNICENTRO |
Texto Completo: | http://tede.unicentro.br:8080/jspui/handle/jspui/1796 |
Resumo: | Considering that a more energetic diet may lead to subacute ruminal acidosis in cattle, the use of Saccharomyces cerevisiae-based additives is believed to minimize the severity of this disease, attenuating its effects on bovine immunity and, consequently, the occurrence of respiratory diseases. For this purpose, 32 heifers of Angus blood were used, with average initial weight of 350 kg and mean age of 11 months, fed on 50% corn silage and 50% concentrate distributed randomly in two control groups (7g / animal / cornbread day) and yeast group (7 g / animal / day of the commercial product containing fresh yeasts). In four moments, leukogram, serum haptoglobin, measured by the ELISA technique was performed; oxidative metabolism of neutrophils by the nitro blue tetrazolium technique and occurrence of respiratory disease by nostril temperature and nasal secretion score. At 105 days, the animals were slaughtered and pulmonary fragments of the ventral cranial lobe were harvested for histopathological evaluation. The animals in the control group showed increased leukocytes, neutrophils and serum haptoglobin, as well as greater clinical signs of respiratory diseases and higher histopathological pneumonia scores. On the other hand, the animals in the yeast group showed lower leukocyte and neutrophil counts, increased neutrophil oxidative metabolism and decreased serum haptoglobin, as well as lower nasal secretion, lower respiratory rate and lower pneumonia scores, allowing the conclusion that live yeasts attenuated the elects of confinement on the innate immune system, resulting in higher animal health. |
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Bertagnon, Heloisa Godoihttp://lattes.cnpq.br/5773536284154541025.517.899-90http://lattes.cnpq.br/7847574745569334Virmond, Maurício Paulo2021-11-26T15:40:27Z2019-02-15Virmond, Maurício Paulo. Efeito imunomodulador de leveduras frescas em novilhas confinadas. 2019. 54 f. Dissertação (Programa de Pós-Graduação em Medicina Veterinária - Mestrado) - Universidade Estadual do Centro-Oeste, Guarapuava-PR.http://tede.unicentro.br:8080/jspui/handle/jspui/1796Considering that a more energetic diet may lead to subacute ruminal acidosis in cattle, the use of Saccharomyces cerevisiae-based additives is believed to minimize the severity of this disease, attenuating its effects on bovine immunity and, consequently, the occurrence of respiratory diseases. For this purpose, 32 heifers of Angus blood were used, with average initial weight of 350 kg and mean age of 11 months, fed on 50% corn silage and 50% concentrate distributed randomly in two control groups (7g / animal / cornbread day) and yeast group (7 g / animal / day of the commercial product containing fresh yeasts). In four moments, leukogram, serum haptoglobin, measured by the ELISA technique was performed; oxidative metabolism of neutrophils by the nitro blue tetrazolium technique and occurrence of respiratory disease by nostril temperature and nasal secretion score. At 105 days, the animals were slaughtered and pulmonary fragments of the ventral cranial lobe were harvested for histopathological evaluation. The animals in the control group showed increased leukocytes, neutrophils and serum haptoglobin, as well as greater clinical signs of respiratory diseases and higher histopathological pneumonia scores. On the other hand, the animals in the yeast group showed lower leukocyte and neutrophil counts, increased neutrophil oxidative metabolism and decreased serum haptoglobin, as well as lower nasal secretion, lower respiratory rate and lower pneumonia scores, allowing the conclusion that live yeasts attenuated the elects of confinement on the innate immune system, resulting in higher animal health.Tendo em vista que uma alimentação mais energética pode propiciar acidose ruminal subaguda em bovinos, acredita-se que o uso de aditivos a base de Sacharomyces cerevisiae viva minimize a gravidade desta enfermidade, atenuando seus efeitos na imunidade bovina e consequentemente na ocorrência de doenças respiratórias. Para tanto utilizou-se 32 novilhas ½ sangue Angus, com peso médio inicial de 350 kg e idade média de 1 1 meses, submetidas a dieta com 50% silagem de milho e 50% concentrado distribuídas aleatoriamente em dois tratamentos grupo controle (7g/animal/dia de quirera de milho) e grupo leveduras (7g/animal/dia do produto comercial contendo leveduras frescas). Em quatro momentos realizou-se avaliações de leucograma, haptoglobina sérica, mensurada pela técnica de ELISA; metabolismo oxidativo de neutrófilos, pela técnica do nitro azul de tetrazolium e ocorrência de doença respiratória pelos indicadores temperatura de narinas e o escore de secreção nasal. Aos 105 dias, os animais foram abatidos e fragmentos pulmonares do lobo cranial ventral foram colhidos para avaliação histopatológica. Observou-se nos animais do grupo controle aumento de leucócitos, neutrófilos e haptoglobina sérica, assim como apresentaram maiores sinais clínicos de doenças respiratórias e maiores escores de pneumonia no histopatológico. Já os animais do grupo levedura manifestaram menores contagens de leucócitos e neutrófilos, aumento do metabolismo oxidativo neutrofílico e diminuição da haptoglobina sérica, além de, menor escore de secreção nasal, de temperatura de narinas e menores escores de pneumonia, permitindo concluir que as leveduras vivas atenuaram os efeitos do confinamento no sistema imune inato, resultando em maior saúde dos animais.Submitted by Fabiano Jucá (fjuca@unicentro.br) on 2021-11-26T15:40:27Z No. of bitstreams: 1 Dissertação Mauricio Paulo Virmond.pdf: 18385084 bytes, checksum: 3a0a2a72637826eaeb2cbea9d0e4a50d (MD5)Made available in DSpace on 2021-11-26T15:40:27Z (GMT). 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dc.title.por.fl_str_mv |
Efeito imunomodulador de leveduras frescas em novilhas confinadas |
dc.title.alternative.eng.fl_str_mv |
Immunomodulatory effect of fresh yeasts on the diet of confined heifers |
title |
Efeito imunomodulador de leveduras frescas em novilhas confinadas |
spellingShingle |
Efeito imunomodulador de leveduras frescas em novilhas confinadas Virmond, Maurício Paulo Imunidade Sacharomyces cerevisiea metabolismo oxidativo haptoglobina Immunity Sacharomyces cerevisiea phagocytosis haptoglobina CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Efeito imunomodulador de leveduras frescas em novilhas confinadas |
title_full |
Efeito imunomodulador de leveduras frescas em novilhas confinadas |
title_fullStr |
Efeito imunomodulador de leveduras frescas em novilhas confinadas |
title_full_unstemmed |
Efeito imunomodulador de leveduras frescas em novilhas confinadas |
title_sort |
Efeito imunomodulador de leveduras frescas em novilhas confinadas |
author |
Virmond, Maurício Paulo |
author_facet |
Virmond, Maurício Paulo |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Bertagnon, Heloisa Godoi |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/5773536284154541 |
dc.contributor.authorID.fl_str_mv |
025.517.899-90 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/7847574745569334 |
dc.contributor.author.fl_str_mv |
Virmond, Maurício Paulo |
contributor_str_mv |
Bertagnon, Heloisa Godoi |
dc.subject.por.fl_str_mv |
Imunidade Sacharomyces cerevisiea metabolismo oxidativo haptoglobina |
topic |
Imunidade Sacharomyces cerevisiea metabolismo oxidativo haptoglobina Immunity Sacharomyces cerevisiea phagocytosis haptoglobina CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.eng.fl_str_mv |
Immunity Sacharomyces cerevisiea phagocytosis haptoglobina |
dc.subject.cnpq.fl_str_mv |
CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
Considering that a more energetic diet may lead to subacute ruminal acidosis in cattle, the use of Saccharomyces cerevisiae-based additives is believed to minimize the severity of this disease, attenuating its effects on bovine immunity and, consequently, the occurrence of respiratory diseases. For this purpose, 32 heifers of Angus blood were used, with average initial weight of 350 kg and mean age of 11 months, fed on 50% corn silage and 50% concentrate distributed randomly in two control groups (7g / animal / cornbread day) and yeast group (7 g / animal / day of the commercial product containing fresh yeasts). In four moments, leukogram, serum haptoglobin, measured by the ELISA technique was performed; oxidative metabolism of neutrophils by the nitro blue tetrazolium technique and occurrence of respiratory disease by nostril temperature and nasal secretion score. At 105 days, the animals were slaughtered and pulmonary fragments of the ventral cranial lobe were harvested for histopathological evaluation. The animals in the control group showed increased leukocytes, neutrophils and serum haptoglobin, as well as greater clinical signs of respiratory diseases and higher histopathological pneumonia scores. On the other hand, the animals in the yeast group showed lower leukocyte and neutrophil counts, increased neutrophil oxidative metabolism and decreased serum haptoglobin, as well as lower nasal secretion, lower respiratory rate and lower pneumonia scores, allowing the conclusion that live yeasts attenuated the elects of confinement on the innate immune system, resulting in higher animal health. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019-02-15 |
dc.date.accessioned.fl_str_mv |
2021-11-26T15:40:27Z |
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info:eu-repo/semantics/masterThesis |
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dc.identifier.citation.fl_str_mv |
Virmond, Maurício Paulo. Efeito imunomodulador de leveduras frescas em novilhas confinadas. 2019. 54 f. Dissertação (Programa de Pós-Graduação em Medicina Veterinária - Mestrado) - Universidade Estadual do Centro-Oeste, Guarapuava-PR. |
dc.identifier.uri.fl_str_mv |
http://tede.unicentro.br:8080/jspui/handle/jspui/1796 |
identifier_str_mv |
Virmond, Maurício Paulo. Efeito imunomodulador de leveduras frescas em novilhas confinadas. 2019. 54 f. Dissertação (Programa de Pós-Graduação em Medicina Veterinária - Mestrado) - Universidade Estadual do Centro-Oeste, Guarapuava-PR. |
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Universidade Estadual do Centro-Oeste |
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Universidade Estadual do Centro-Oeste |
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