Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas

Detalhes bibliográficos
Autor(a) principal: Batista, Gillane Rosas
Data de Publicação: 2019
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da Universidade do Estado do Amazonas (UEA)
Texto Completo: https://ri.uea.edu.br/handle/riuea/6383
Resumo: Easy acess to drug purchase and self-medication are factors rooted in Brazilian customs, such factors increase the incorrect disposal the medicaments in the environment consequently, drugs such as acetaminophen are found in natural system. With the focus of degrading acetaminophen. Heterogeneous photocatalysis has been an efficient means study to removed. Within this problematic this work has objective the study of acetaminophen degradation by heterogeneous photocatalysis using the titanium dioxide catalyst. This work studied of the influence of time, pH and the presence catalyst on conversion of the drug. In experimental design was studied: time the 1 and 2h, pH 5 and 9 and for the catalyst observed drug conversion with the same without. The study was carried out through an experiment in a photocatalytic batch reactor, where the solution containing the drug was placed in a 1 L volume vat and the placed in a parallelepiped shaped reactor 27 x 54,8 x 20 cm and a 36 W bulb couple inside the reactor. In all, 16 were performed, as a duplicate was required, and the system response was to observe the conversion of drug. By analyzing the Pareto diagram, the variables studied were not significant for the system response, however the results show that even in low amounts it was possible to degrade the drug. However the results show that even in low amounts drug degradation possible. The highest degradation was 17,42%, obtained pH = 9, the time of 2 hrs and without the catalyst, but it was observed that the solution that had catalyst had degradation in more than one assay. It was concluded that the proposed model was not significant for this process, but it was possible observe the degradation of acetaminophen by effects of time and pH.
id UEA_fb0865b95e27f307f56384aa974b4757
oai_identifier_str oai:ri.uea.edu.br:riuea/6383
network_acronym_str UEA
network_name_str Repositório Institucional da Universidade do Estado do Amazonas (UEA)
repository_id_str
spelling Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea AmazônicasStudy of paracetamol (acetaminophen) degradation by heterogeneous Amazonian photocatalysisFotocatálise heterogêneaContaminantesDióxido de titânioHeterogeneous PhotocatalysisContaminateTitanium dioxideMedicamentosEasy acess to drug purchase and self-medication are factors rooted in Brazilian customs, such factors increase the incorrect disposal the medicaments in the environment consequently, drugs such as acetaminophen are found in natural system. With the focus of degrading acetaminophen. Heterogeneous photocatalysis has been an efficient means study to removed. Within this problematic this work has objective the study of acetaminophen degradation by heterogeneous photocatalysis using the titanium dioxide catalyst. This work studied of the influence of time, pH and the presence catalyst on conversion of the drug. In experimental design was studied: time the 1 and 2h, pH 5 and 9 and for the catalyst observed drug conversion with the same without. The study was carried out through an experiment in a photocatalytic batch reactor, where the solution containing the drug was placed in a 1 L volume vat and the placed in a parallelepiped shaped reactor 27 x 54,8 x 20 cm and a 36 W bulb couple inside the reactor. In all, 16 were performed, as a duplicate was required, and the system response was to observe the conversion of drug. By analyzing the Pareto diagram, the variables studied were not significant for the system response, however the results show that even in low amounts it was possible to degrade the drug. However the results show that even in low amounts drug degradation possible. The highest degradation was 17,42%, obtained pH = 9, the time of 2 hrs and without the catalyst, but it was observed that the solution that had catalyst had degradation in more than one assay. It was concluded that the proposed model was not significant for this process, but it was possible observe the degradation of acetaminophen by effects of time and pH.O acesso facilitado a compra de fármacos e a automedicação são fatores enraizados nos costumes brasileiros, tais fatores aumentam o descarte incorreto de medicamentos no meio ambiente, consequentemente, medicamentos como paracetamol são cada vez mais encontrados em sistemas naturais. Dentro dessa problemática, este trabalho teve como objetivo o estudo da degradação de paracetamol por fotocatálise heterogênea usando o catalisador dióxido de titânio. Esse trabalho estudou a influência do tempo, pH e a presença do catalisador na conversão de paracetamol. No planejamento experimental, foram estudados tempo de 1 e 2 h, ph 5 e 9 e ausência e presença do catalisador. O estudo foi feito através de experimento em um reator batelada fotocatalítico, onde a solução contendo o fármaco foi colocada num recipiente com volume de 1 L e o mesmo posto no reator em formato de paralelepípedo com dimensões 27 x 54,8 x 20 cm e uma lâmpada de 36 W acoplado dentro do reator. Ao todo foram feitos 16 experimentos, devido a duplicata, e a resposta do sistema era observar a degradação do fármaco. Fazendo a análise do diagrama de Pareto, as variáveis estudadas não foram significativas para a resposta do sistema, contudo os resultados mostram que mesmo em quantidades baixas foi possível a degradação de fármaco. A maior degradação foi de 17,42%, obtido em pH= 9, o tempo de 2hrs e sem o catalisador, no entanto observou-se que soluções com catalisador apresentou degradação em mais de um ensaio. Conclui-se que o modelo proposto não foi estatisticamente significativo para esse processo, mas foi possível observar a degradação de paracetamol pelos efeitos do tempo e de pH.Universidade do Estado do AmazonasBrasilUEAPinheiro, Clairon LimaSouza, Cristiane Daliassi Ramos deSouza, Érica Simplício deBatista, Gillane Rosas2020-03-31T22:31:09Z2024-09-30T17:15:03Z2020-03-272020-03-31T22:31:09Z2019-12-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisapplication/pdfhttps://ri.uea.edu.br/handle/riuea/6383porAtribuição-NãoComercial-SemDerivados 3.0 Brasilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessreponame:Repositório Institucional da Universidade do Estado do Amazonas (UEA)instname:Universidade do Estado do Amazonas (UEA)instacron:UEA2024-10-01T00:55:14Zoai:ri.uea.edu.br:riuea/6383Repositório InstitucionalPUBhttps://ri.uea.edu.br/server/oai/requestbibliotecacentral@uea.edu.bropendoar:2024-10-01T00:55:14Repositório Institucional da Universidade do Estado do Amazonas (UEA) - Universidade do Estado do Amazonas (UEA)false
dc.title.none.fl_str_mv Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
Study of paracetamol (acetaminophen) degradation by heterogeneous Amazonian photocatalysis
title Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
spellingShingle Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
Batista, Gillane Rosas
Fotocatálise heterogênea
Contaminantes
Dióxido de titânio
Heterogeneous Photocatalysis
Contaminate
Titanium dioxide
Medicamentos
title_short Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
title_full Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
title_fullStr Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
title_full_unstemmed Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
title_sort Estudo da degradação do paracetamol (acetaminofeno) por fotocatálise heterogênea Amazônicas
author Batista, Gillane Rosas
author_facet Batista, Gillane Rosas
author_role author
dc.contributor.none.fl_str_mv Pinheiro, Clairon Lima
Souza, Cristiane Daliassi Ramos de
Souza, Érica Simplício de
dc.contributor.author.fl_str_mv Batista, Gillane Rosas
dc.subject.por.fl_str_mv Fotocatálise heterogênea
Contaminantes
Dióxido de titânio
Heterogeneous Photocatalysis
Contaminate
Titanium dioxide
Medicamentos
topic Fotocatálise heterogênea
Contaminantes
Dióxido de titânio
Heterogeneous Photocatalysis
Contaminate
Titanium dioxide
Medicamentos
description Easy acess to drug purchase and self-medication are factors rooted in Brazilian customs, such factors increase the incorrect disposal the medicaments in the environment consequently, drugs such as acetaminophen are found in natural system. With the focus of degrading acetaminophen. Heterogeneous photocatalysis has been an efficient means study to removed. Within this problematic this work has objective the study of acetaminophen degradation by heterogeneous photocatalysis using the titanium dioxide catalyst. This work studied of the influence of time, pH and the presence catalyst on conversion of the drug. In experimental design was studied: time the 1 and 2h, pH 5 and 9 and for the catalyst observed drug conversion with the same without. The study was carried out through an experiment in a photocatalytic batch reactor, where the solution containing the drug was placed in a 1 L volume vat and the placed in a parallelepiped shaped reactor 27 x 54,8 x 20 cm and a 36 W bulb couple inside the reactor. In all, 16 were performed, as a duplicate was required, and the system response was to observe the conversion of drug. By analyzing the Pareto diagram, the variables studied were not significant for the system response, however the results show that even in low amounts it was possible to degrade the drug. However the results show that even in low amounts drug degradation possible. The highest degradation was 17,42%, obtained pH = 9, the time of 2 hrs and without the catalyst, but it was observed that the solution that had catalyst had degradation in more than one assay. It was concluded that the proposed model was not significant for this process, but it was possible observe the degradation of acetaminophen by effects of time and pH.
publishDate 2019
dc.date.none.fl_str_mv 2019-12-12
2020-03-31T22:31:09Z
2020-03-27
2020-03-31T22:31:09Z
2024-09-30T17:15:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bachelorThesis
format bachelorThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ri.uea.edu.br/handle/riuea/6383
url https://ri.uea.edu.br/handle/riuea/6383
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv Atribuição-NãoComercial-SemDerivados 3.0 Brasil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribuição-NãoComercial-SemDerivados 3.0 Brasil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade do Estado do Amazonas
Brasil
UEA
publisher.none.fl_str_mv Universidade do Estado do Amazonas
Brasil
UEA
dc.source.none.fl_str_mv reponame:Repositório Institucional da Universidade do Estado do Amazonas (UEA)
instname:Universidade do Estado do Amazonas (UEA)
instacron:UEA
instname_str Universidade do Estado do Amazonas (UEA)
instacron_str UEA
institution UEA
reponame_str Repositório Institucional da Universidade do Estado do Amazonas (UEA)
collection Repositório Institucional da Universidade do Estado do Amazonas (UEA)
repository.name.fl_str_mv Repositório Institucional da Universidade do Estado do Amazonas (UEA) - Universidade do Estado do Amazonas (UEA)
repository.mail.fl_str_mv bibliotecacentral@uea.edu.br
_version_ 1823241946462683136