Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis

Bibliographic Details
Main Author: Santarém, Vamilton Alvares
Publication Date: 2008
Other Authors: José, Melina de Deus, Laposy, Cecília Braga
Format: Article
Language: por
Source: Semina. Ciências Agrárias (Online)
Download full: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2719
Summary: In order to study the biochemical changes in naturally infected dogs with Ehrlichia canis, blood samples from 57 animals were collected. Thirty-five healthy dogs were used as control group. Dosage of serum protein, albumin, globulin, albumin:globulin ratio (A:G), urea, creatinine, alanine aminotransferase (ALT) e alkaline phosphatase (AP) were carried out. The comparison of mean in infected and control group as well as the distribution of frequencies were investigated in order to associate the disease to the findings. Hypoproteinemia, hypoalbuminemia, decreased A:G ratio, hyperglobulinemia, and uremia were associated to ehrlichiosis (p < 0.05). Regarding pancytopenia, it was observed that ALT and creatinine were, respectively, the marker of ehrlichiosis in non pancytopenic (NP) and pancytopenic (P) dogs. There were no significantly differences in protein profile in NP and P dogs that support the presence of a marker for the disease.
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spelling Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosisAlterações bioquímicas em cães citopênicos e não citopênicos com ehrlichioseCanineEhrlichiosisRickettsiosisBiochemistry.CaninoEhrlichioseRickettsioseBioquímica.In order to study the biochemical changes in naturally infected dogs with Ehrlichia canis, blood samples from 57 animals were collected. Thirty-five healthy dogs were used as control group. Dosage of serum protein, albumin, globulin, albumin:globulin ratio (A:G), urea, creatinine, alanine aminotransferase (ALT) e alkaline phosphatase (AP) were carried out. The comparison of mean in infected and control group as well as the distribution of frequencies were investigated in order to associate the disease to the findings. Hypoproteinemia, hypoalbuminemia, decreased A:G ratio, hyperglobulinemia, and uremia were associated to ehrlichiosis (p < 0.05). Regarding pancytopenia, it was observed that ALT and creatinine were, respectively, the marker of ehrlichiosis in non pancytopenic (NP) and pancytopenic (P) dogs. There were no significantly differences in protein profile in NP and P dogs that support the presence of a marker for the disease.Com o objetivo de estudar os parâmetros bioquímicos associados às funções renal e hepática em cães naturalmente infectados por Ehrlichia canis e associá-los à ehrlichiose, foram colhidas 57 amostras de sangue, com realização de dosagem de proteína plasmática total, albumina, globulina, relação albumina/ globulina (A/G), uréia, creatinina, alanino aminotransferase (ALT) e fosfatase alcalina (FA). Outros 35 cães em higidez foram utilizados como controle. Foram comparadas as médias dos animais infectados e controle, bem como a distribuição de freqüências, para associação dos resultados com a doença. Hipoproteinemia, hipoalbuminemia, redução da A/G, hiperglobulinemia e aumento de uréia estiveram associados à doença (p < 0,05). Foram comparados também os achados entre animais não pancitopênicos (NPan) e em pancitopenia (Pan), verificando-se que no primeiro grupo, houve aumento de ALT, e nos animais pancitopênicos, a creatinina foi o principal indicador de ehrlichiose. No caso do perfil protéico, não houve diferença que pudesse servir como marcador da fase da enfermidade nos animais infectados.UEL2008-08-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/271910.5433/1679-0359.2008v29n4p845Semina: Ciências Agrárias; Vol. 29 No. 4 (2008); 845-852Semina: Ciências Agrárias; v. 29 n. 4 (2008); 845-8521679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2719/4061Santarém, Vamilton AlvaresJosé, Melina de DeusLaposy, Cecília Bragainfo:eu-repo/semantics/openAccess2015-11-19T18:38:42Zoai:ojs.pkp.sfu.ca:article/2719Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2015-11-19T18:38:42Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
Alterações bioquímicas em cães citopênicos e não citopênicos com ehrlichiose
title Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
spellingShingle Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
Santarém, Vamilton Alvares
Canine
Ehrlichiosis
Rickettsiosis
Biochemistry.
Canino
Ehrlichiose
Rickettsiose
Bioquímica.
title_short Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
title_full Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
title_fullStr Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
title_full_unstemmed Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
title_sort Biochemical changes in pancytopenic and non pancytopenic dogs with ehrlichiosis
author Santarém, Vamilton Alvares
author_facet Santarém, Vamilton Alvares
José, Melina de Deus
Laposy, Cecília Braga
author_role author
author2 José, Melina de Deus
Laposy, Cecília Braga
author2_role author
author
dc.contributor.author.fl_str_mv Santarém, Vamilton Alvares
José, Melina de Deus
Laposy, Cecília Braga
dc.subject.por.fl_str_mv Canine
Ehrlichiosis
Rickettsiosis
Biochemistry.
Canino
Ehrlichiose
Rickettsiose
Bioquímica.
topic Canine
Ehrlichiosis
Rickettsiosis
Biochemistry.
Canino
Ehrlichiose
Rickettsiose
Bioquímica.
description In order to study the biochemical changes in naturally infected dogs with Ehrlichia canis, blood samples from 57 animals were collected. Thirty-five healthy dogs were used as control group. Dosage of serum protein, albumin, globulin, albumin:globulin ratio (A:G), urea, creatinine, alanine aminotransferase (ALT) e alkaline phosphatase (AP) were carried out. The comparison of mean in infected and control group as well as the distribution of frequencies were investigated in order to associate the disease to the findings. Hypoproteinemia, hypoalbuminemia, decreased A:G ratio, hyperglobulinemia, and uremia were associated to ehrlichiosis (p < 0.05). Regarding pancytopenia, it was observed that ALT and creatinine were, respectively, the marker of ehrlichiosis in non pancytopenic (NP) and pancytopenic (P) dogs. There were no significantly differences in protein profile in NP and P dogs that support the presence of a marker for the disease.
publishDate 2008
dc.date.none.fl_str_mv 2008-08-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2719
10.5433/1679-0359.2008v29n4p845
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2719
identifier_str_mv 10.5433/1679-0359.2008v29n4p845
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2719/4061
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 29 No. 4 (2008); 845-852
Semina: Ciências Agrárias; v. 29 n. 4 (2008); 845-852
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
_version_ 1799306058713268224

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