The importance of Gram positive bacteria as the cause of canine pyometra
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Publication Date: | 2017 |
Other Authors: | , , , , |
Format: | Article |
Language: | eng |
Source: | Semina. Ciências Agrárias (Online) |
Download full: | https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/25113 |
Summary: | E. coli is the main bacteria isolated from infected uterus and bacterial endotoxin can lead to fatal endotoxic shock. Systemic inflammatory response syndrome (SIRS) precedes the endotoxic shock. Thus, early recognition of SIRS is important for patient treatment and prognostic. In Brazil, Gram positive bacteria are responsible for approximately 20% of all pyometra cases, and there is limited information about pathophysiology of shock and tissue injury. The aim of this study was to investigate the capacity of Gram positive bacteria to cause SIRS in bitches with pyometra. A prospective follow-up of 67 bitches with pyometra was performed, which were classified as SIRS + and SIRS- on admission. All bitches were surgically treated (ovariohysterectomy), uterine contents were collected in a sterile manner and the material was submitted to microbiological evaluation. Were identified in 55.2% of bitches E. coli (G1), 23.9% other Gram negative bacteria (G2) and 20.9% Gram positive bacteria (G3). The leukocyte profile, serum biochemistry and prevalence of SIRS were similar between the groups. It is concluded that Gram positive bacteria have the capacity to promote tissue damage and can lead the patient to death after SIRS and shock, as well as by E. coli and other Gram negative. |
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The importance of Gram positive bacteria as the cause of canine pyometraA importância de bactérias Gram positivas como etiologia na piometra caninaBacteria etiologyCystic endometrial hyperplasiaSIRS.Etiologia bacterianaHiperplasia endometrial císticaSIRS.E. coli is the main bacteria isolated from infected uterus and bacterial endotoxin can lead to fatal endotoxic shock. Systemic inflammatory response syndrome (SIRS) precedes the endotoxic shock. Thus, early recognition of SIRS is important for patient treatment and prognostic. In Brazil, Gram positive bacteria are responsible for approximately 20% of all pyometra cases, and there is limited information about pathophysiology of shock and tissue injury. The aim of this study was to investigate the capacity of Gram positive bacteria to cause SIRS in bitches with pyometra. A prospective follow-up of 67 bitches with pyometra was performed, which were classified as SIRS + and SIRS- on admission. All bitches were surgically treated (ovariohysterectomy), uterine contents were collected in a sterile manner and the material was submitted to microbiological evaluation. Were identified in 55.2% of bitches E. coli (G1), 23.9% other Gram negative bacteria (G2) and 20.9% Gram positive bacteria (G3). The leukocyte profile, serum biochemistry and prevalence of SIRS were similar between the groups. It is concluded that Gram positive bacteria have the capacity to promote tissue damage and can lead the patient to death after SIRS and shock, as well as by E. coli and other Gram negative.A Escherichia coli é reportada como principal agente etiológico da piometra canina e as endotoxinas bacterianas podem desencadear choque endotóxico e óbito. A síndrome da resposta inflamatória sistêmica (SIRS) antecede o choque e sua identificação pode predizer o prognóstico do paciente. No Brasil, bactérias Gram positivas são responsáveis por aproximadamente 20% dos casos de piometra, e informações a respeito da fisiopatologia do choque ou da lesão tecidual nesses casos são escassos. Assim, o objetivo foi investigar a capacidade de bactérias Gram positivas desencadear SIRS em cadelas com piometra. Foram acompanhadas de maneira prospectiva 67 cadelas com piometra, que na admissão passaram por exame clínico, exames laboratoriais e foram classificadas como SIRS+ e SIRS-. Todos os animais foram tratados cirurgicamente (ovariohisterectomia), o conteúdo uterino foi coletado de forma estéril e o material foi submetido à avaliação microbiológica. Em 55,2% das cadelas foi identificada E. coli (G1), 23,9% outras bactérias Gram negativas (G2) e 20,9% Gram positivas (G3). O perfil leucocitário, a bioquímica sérica e a prevalência de SIRS foram semelhantes entre os grupos. Conclui-se que bactérias Gram positivas possuem capacidade de promover dano tecidual podendo levar o paciente a óbito após desencadear SIRS e choque, assim como por E. coli e outras Gram negativas.UEL2017-05-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionEstudo prospectivo; Etiologia bacteriana na piometra canina; Síndrome da resposta inflamatória sistêmicaAvaliado por paresapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2511310.5433/1679-0359.2017v38n2p1077Semina: Ciências Agrárias; Vol. 38 No. 2 (2017); 1077-1082Semina: Ciências Agrárias; v. 38 n. 2 (2017); 1077-10821679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/25113/20841Copyright (c) 2017 Semina: Ciências Agráriashttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessSant' anna, Marcos CezarTrautwein, Luiz Guilherme CorsiGiordano, Lucienne Garcia PrettoJustino, Rebeca CordeiroFlaiban, Karina Keller Marques da CostaMartins, Maria Isabel Mello2022-11-18T12:54:42Zoai:ojs.pkp.sfu.ca:article/25113Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2022-11-18T12:54:42Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false |
dc.title.none.fl_str_mv |
The importance of Gram positive bacteria as the cause of canine pyometra A importância de bactérias Gram positivas como etiologia na piometra canina |
title |
The importance of Gram positive bacteria as the cause of canine pyometra |
spellingShingle |
The importance of Gram positive bacteria as the cause of canine pyometra Sant' anna, Marcos Cezar Bacteria etiology Cystic endometrial hyperplasia SIRS. Etiologia bacteriana Hiperplasia endometrial cística SIRS. |
title_short |
The importance of Gram positive bacteria as the cause of canine pyometra |
title_full |
The importance of Gram positive bacteria as the cause of canine pyometra |
title_fullStr |
The importance of Gram positive bacteria as the cause of canine pyometra |
title_full_unstemmed |
The importance of Gram positive bacteria as the cause of canine pyometra |
title_sort |
The importance of Gram positive bacteria as the cause of canine pyometra |
author |
Sant' anna, Marcos Cezar |
author_facet |
Sant' anna, Marcos Cezar Trautwein, Luiz Guilherme Corsi Giordano, Lucienne Garcia Pretto Justino, Rebeca Cordeiro Flaiban, Karina Keller Marques da Costa Martins, Maria Isabel Mello |
author_role |
author |
author2 |
Trautwein, Luiz Guilherme Corsi Giordano, Lucienne Garcia Pretto Justino, Rebeca Cordeiro Flaiban, Karina Keller Marques da Costa Martins, Maria Isabel Mello |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Sant' anna, Marcos Cezar Trautwein, Luiz Guilherme Corsi Giordano, Lucienne Garcia Pretto Justino, Rebeca Cordeiro Flaiban, Karina Keller Marques da Costa Martins, Maria Isabel Mello |
dc.subject.por.fl_str_mv |
Bacteria etiology Cystic endometrial hyperplasia SIRS. Etiologia bacteriana Hiperplasia endometrial cística SIRS. |
topic |
Bacteria etiology Cystic endometrial hyperplasia SIRS. Etiologia bacteriana Hiperplasia endometrial cística SIRS. |
description |
E. coli is the main bacteria isolated from infected uterus and bacterial endotoxin can lead to fatal endotoxic shock. Systemic inflammatory response syndrome (SIRS) precedes the endotoxic shock. Thus, early recognition of SIRS is important for patient treatment and prognostic. In Brazil, Gram positive bacteria are responsible for approximately 20% of all pyometra cases, and there is limited information about pathophysiology of shock and tissue injury. The aim of this study was to investigate the capacity of Gram positive bacteria to cause SIRS in bitches with pyometra. A prospective follow-up of 67 bitches with pyometra was performed, which were classified as SIRS + and SIRS- on admission. All bitches were surgically treated (ovariohysterectomy), uterine contents were collected in a sterile manner and the material was submitted to microbiological evaluation. Were identified in 55.2% of bitches E. coli (G1), 23.9% other Gram negative bacteria (G2) and 20.9% Gram positive bacteria (G3). The leukocyte profile, serum biochemistry and prevalence of SIRS were similar between the groups. It is concluded that Gram positive bacteria have the capacity to promote tissue damage and can lead the patient to death after SIRS and shock, as well as by E. coli and other Gram negative. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-05-02 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Estudo prospectivo; Etiologia bacteriana na piometra canina; Síndrome da resposta inflamatória sistêmica Avaliado por pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/25113 10.5433/1679-0359.2017v38n2p1077 |
url |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/25113 |
identifier_str_mv |
10.5433/1679-0359.2017v38n2p1077 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/25113/20841 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UEL |
publisher.none.fl_str_mv |
UEL |
dc.source.none.fl_str_mv |
Semina: Ciências Agrárias; Vol. 38 No. 2 (2017); 1077-1082 Semina: Ciências Agrárias; v. 38 n. 2 (2017); 1077-1082 1679-0359 1676-546X reponame:Semina. Ciências Agrárias (Online) instname:Universidade Estadual de Londrina (UEL) instacron:UEL |
instname_str |
Universidade Estadual de Londrina (UEL) |
instacron_str |
UEL |
institution |
UEL |
reponame_str |
Semina. Ciências Agrárias (Online) |
collection |
Semina. Ciências Agrárias (Online) |
repository.name.fl_str_mv |
Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL) |
repository.mail.fl_str_mv |
semina.agrarias@uel.br |
_version_ |
1799306075723268096 |