Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment

Detalhes bibliográficos
Autor(a) principal: Carvalho, Armando de Mattos
Data de Publicação: 2016
Outros Autores: Hussni, Carlos Alberto, Alves, Ana Liz Garcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/22743
Resumo: Tendinitis is an important high-relapse-rate disease, which compromises equine performance and may result in early athletic life end to affected animals. Many therapies have been set to treat equine tendinitis; however, just few result in improved relapse rates, quality of extracellular matrix (ECM) and increased biomechanical resistance of the treated tissue. Due to advances in the regenerative medicine, promising results were initially obtained through the implantation of mesenchymal stem cells (MSC) derived from the bone marrow in the equine tendon injury. Since then, many studies have been using MSCs from different sources for therapeutic means in equine. The adipose tissue has appeared as feasible MSC source. There are promising results involving equine tendinitis therapy using mesenchymal stem cells from adipose tissue (AdMSCs).
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spelling Adipose tissue as mesenchymal stem cells source in equine tendinitis treatmentTecido adiposo como fonte de células tronco mesenquimais no tratamento da tendinite equinaTendonTherapyStem cellsRegenerative medicine.TendãoTerapiaCélulas troncoMedicina regenerativa.Tendinitis is an important high-relapse-rate disease, which compromises equine performance and may result in early athletic life end to affected animals. Many therapies have been set to treat equine tendinitis; however, just few result in improved relapse rates, quality of extracellular matrix (ECM) and increased biomechanical resistance of the treated tissue. Due to advances in the regenerative medicine, promising results were initially obtained through the implantation of mesenchymal stem cells (MSC) derived from the bone marrow in the equine tendon injury. Since then, many studies have been using MSCs from different sources for therapeutic means in equine. The adipose tissue has appeared as feasible MSC source. There are promising results involving equine tendinitis therapy using mesenchymal stem cells from adipose tissue (AdMSCs).A tendinite é uma importante afecção com alta taxa de recidivas que compromete o desempenho de equinos e pode resultar no término precoce da vida atlética dos animais acometidos. Diversas terapias têm sido estabelecidas para o tratamento da tendinite equina, no entanto poucas resultam na melhora da taxa de recidiva, melhora da qualidade da matriz extracelular (MEC) e aumento da resistência biomecânica do tecido tratado. Com o advento da medicina regenerativa resultados promissores foram inicialmente obtidos com o implante de células tronco mesenquimais (CTMs) derivadas da medula óssea na lesão tendínea de equinos. Desde então, diversos estudos têm sido conduzidos utilizando CTMs de diferentes fontes para esta finalidade terapêutica em equinos. O tecido adiposo tem se mostrado como uma fonte viável de CTMs e também há resultados promissores envolvendo a terapia da tendinite equina utilizando as células tronco mesenquimais derivadas do tecido adiposo (AdCTMs). Neste artigo, dados relacionados ao uso das AdCTMs na terapia da tendinite equina serão revisados.UEL2016-12-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de LiteraturaRevisão de Literaturaapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2274310.5433/1679-0359.2016v37n6p4179Semina: Ciências Agrárias; Vol. 37 No. 6 (2016); 4179-4192Semina: Ciências Agrárias; v. 37 n. 6 (2016); 4179-41921679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/22743/20101http://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessCarvalho, Armando de MattosHussni, Carlos AlbertoAlves, Ana Liz Garcia2022-11-29T16:29:26Zoai:ojs.pkp.sfu.ca:article/22743Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2022-11-29T16:29:26Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
Tecido adiposo como fonte de células tronco mesenquimais no tratamento da tendinite equina
title Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
spellingShingle Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
Carvalho, Armando de Mattos
Tendon
Therapy
Stem cells
Regenerative medicine.
Tendão
Terapia
Células tronco
Medicina regenerativa.
title_short Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
title_full Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
title_fullStr Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
title_full_unstemmed Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
title_sort Adipose tissue as mesenchymal stem cells source in equine tendinitis treatment
author Carvalho, Armando de Mattos
author_facet Carvalho, Armando de Mattos
Hussni, Carlos Alberto
Alves, Ana Liz Garcia
author_role author
author2 Hussni, Carlos Alberto
Alves, Ana Liz Garcia
author2_role author
author
dc.contributor.author.fl_str_mv Carvalho, Armando de Mattos
Hussni, Carlos Alberto
Alves, Ana Liz Garcia
dc.subject.por.fl_str_mv Tendon
Therapy
Stem cells
Regenerative medicine.
Tendão
Terapia
Células tronco
Medicina regenerativa.
topic Tendon
Therapy
Stem cells
Regenerative medicine.
Tendão
Terapia
Células tronco
Medicina regenerativa.
description Tendinitis is an important high-relapse-rate disease, which compromises equine performance and may result in early athletic life end to affected animals. Many therapies have been set to treat equine tendinitis; however, just few result in improved relapse rates, quality of extracellular matrix (ECM) and increased biomechanical resistance of the treated tissue. Due to advances in the regenerative medicine, promising results were initially obtained through the implantation of mesenchymal stem cells (MSC) derived from the bone marrow in the equine tendon injury. Since then, many studies have been using MSCs from different sources for therapeutic means in equine. The adipose tissue has appeared as feasible MSC source. There are promising results involving equine tendinitis therapy using mesenchymal stem cells from adipose tissue (AdMSCs).
publishDate 2016
dc.date.none.fl_str_mv 2016-12-14
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de Literatura
Revisão de Literatura
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/22743
10.5433/1679-0359.2016v37n6p4179
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/22743
identifier_str_mv 10.5433/1679-0359.2016v37n6p4179
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/22743/20101
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 37 No. 6 (2016); 4179-4192
Semina: Ciências Agrárias; v. 37 n. 6 (2016); 4179-4192
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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