Efect of verminosis on goat immune response

Detalhes bibliográficos
Autor(a) principal: Silva, Marilene Machado
Data de Publicação: 2002
Outros Autores: Faria Junior, Sebastião Pereira de, Martins, Maria de Fátima, Rabello, Patrícia, Pascoal, Patrícia Maria, Bertagnon, Heloísa Godoy, Scheibel, Monika, Garcia, Maurício
Tipo de documento: Artigo
Idioma: por
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2061
Resumo: The purpose of this work was to evaluate the immune response in goats with different degrees of gastrintestinal nematode infection. Ninety adult animals naturally infected were grouped according to the total egg count per feces gram (EPG): group I from zero to 500 EPG, group II from 501 to 2000 and group III above 2000. The parameters studied were serum total protein (STP), evaluated by biuret method; globulin (Glob), calculated by the difference between STP and serum albumin; gammaglobulin (Gglob), estimated throughout electrophoresis; immunoglobulin (Ig), estimated by turbidometry test with ZnSO4 and absolute lymphocyte count (Lymp / ml). It was found statistically decrease in three parameters (STP, Ig and Lymp / ml) for group III. For Glob and Gglob, the decrease found was not statistically significant. These results show a depressor effect of nematode infection on humoral immune system. The intense dispersion of Glob and Gglob data can explain the not significant decrease found in those parameters. It was concluded that goats with intense nematode infection (above 2000 EPG) can show immunedepression, with impairment of lymphocyte count and serum antibody level.
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spelling Efect of verminosis on goat immune responseEfeito da verminose na resposta imune em caprinosCaprineVerminosisImmunossupression.CaprinosVerminoseImunodepressão.The purpose of this work was to evaluate the immune response in goats with different degrees of gastrintestinal nematode infection. Ninety adult animals naturally infected were grouped according to the total egg count per feces gram (EPG): group I from zero to 500 EPG, group II from 501 to 2000 and group III above 2000. The parameters studied were serum total protein (STP), evaluated by biuret method; globulin (Glob), calculated by the difference between STP and serum albumin; gammaglobulin (Gglob), estimated throughout electrophoresis; immunoglobulin (Ig), estimated by turbidometry test with ZnSO4 and absolute lymphocyte count (Lymp / ml). It was found statistically decrease in three parameters (STP, Ig and Lymp / ml) for group III. For Glob and Gglob, the decrease found was not statistically significant. These results show a depressor effect of nematode infection on humoral immune system. The intense dispersion of Glob and Gglob data can explain the not significant decrease found in those parameters. It was concluded that goats with intense nematode infection (above 2000 EPG) can show immunedepression, with impairment of lymphocyte count and serum antibody level.O objetivo deste trabalho foi estudar a resposta imunológica em caprinos com vários graus de verminose gastrintestinal. Foram utilizados 90 animais adultos, naturalmente infectados, divididos em três grupos de 30 animais cada e separados segundo a contagem de ovos por grama de fezes (OPG): grupo I de zero a 500 OPG; grupo II de 501 a 2.000 OPG e o grupo III maior que 2.000 OPG. As variáveis estudadas foram: a dosagem de proteínas séricas totais (PST), avaliada pelo método do biureto; globulinas (Glob), calculada pela diferença entre a proteína total e a albumina sérica; gamaglobulinas (Gglob), medidas pela eletroforese; imunoglobulinas (Ig), dosadas pelo teste da turbidimetria com ZnSO4 e a contagem absoluta de linfócitos (Linfo/mL). Observou-se que em três destes parâmetros (PST, Ig e Linfo/mL) houve queda estatisticamente significativa para o grupo mais infectado. Para a Glob e Gglob a queda não foi significativa. A diminuição destes parâmetros denota um efeito depressor da helmintose sobre o sistema imune humoral. O fato da dosagem de Glob e Gglob não ser estatisticamente menor pode ser explicado pela ocorrência de uma maior dispersão destes resultados. Conclui-se, assim, que caprinos acometidos de intensa helmintose gastrintestinal (acima de 2000 OPG) mostraram-se imunodeprimidos, com linfopenia e diminuição dos níveis séricos de anticorpos.UEL2002-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/206110.5433/1679-0359.2002v23n1p15Semina: Ciências Agrárias; Vol. 23 No. 1 (2002); 15-19Semina: Ciências Agrárias; v. 23 n. 1 (2002); 15-191679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2061/1770Silva, Marilene MachadoFaria Junior, Sebastião Pereira deMartins, Maria de FátimaRabello, PatríciaPascoal, Patrícia MariaBertagnon, Heloísa GodoyScheibel, MonikaGarcia, Maurícioinfo:eu-repo/semantics/openAccess2009-05-20T18:21:41Zoai:ojs.pkp.sfu.ca:article/2061Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2009-05-20T18:21:41Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Efect of verminosis on goat immune response
Efeito da verminose na resposta imune em caprinos
title Efect of verminosis on goat immune response
spellingShingle Efect of verminosis on goat immune response
Silva, Marilene Machado
Caprine
Verminosis
Immunossupression.
Caprinos
Verminose
Imunodepressão.
title_short Efect of verminosis on goat immune response
title_full Efect of verminosis on goat immune response
title_fullStr Efect of verminosis on goat immune response
title_full_unstemmed Efect of verminosis on goat immune response
title_sort Efect of verminosis on goat immune response
author Silva, Marilene Machado
author_facet Silva, Marilene Machado
Faria Junior, Sebastião Pereira de
Martins, Maria de Fátima
Rabello, Patrícia
Pascoal, Patrícia Maria
Bertagnon, Heloísa Godoy
Scheibel, Monika
Garcia, Maurício
author_role author
author2 Faria Junior, Sebastião Pereira de
Martins, Maria de Fátima
Rabello, Patrícia
Pascoal, Patrícia Maria
Bertagnon, Heloísa Godoy
Scheibel, Monika
Garcia, Maurício
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Marilene Machado
Faria Junior, Sebastião Pereira de
Martins, Maria de Fátima
Rabello, Patrícia
Pascoal, Patrícia Maria
Bertagnon, Heloísa Godoy
Scheibel, Monika
Garcia, Maurício
dc.subject.por.fl_str_mv Caprine
Verminosis
Immunossupression.
Caprinos
Verminose
Imunodepressão.
topic Caprine
Verminosis
Immunossupression.
Caprinos
Verminose
Imunodepressão.
description The purpose of this work was to evaluate the immune response in goats with different degrees of gastrintestinal nematode infection. Ninety adult animals naturally infected were grouped according to the total egg count per feces gram (EPG): group I from zero to 500 EPG, group II from 501 to 2000 and group III above 2000. The parameters studied were serum total protein (STP), evaluated by biuret method; globulin (Glob), calculated by the difference between STP and serum albumin; gammaglobulin (Gglob), estimated throughout electrophoresis; immunoglobulin (Ig), estimated by turbidometry test with ZnSO4 and absolute lymphocyte count (Lymp / ml). It was found statistically decrease in three parameters (STP, Ig and Lymp / ml) for group III. For Glob and Gglob, the decrease found was not statistically significant. These results show a depressor effect of nematode infection on humoral immune system. The intense dispersion of Glob and Gglob data can explain the not significant decrease found in those parameters. It was concluded that goats with intense nematode infection (above 2000 EPG) can show immunedepression, with impairment of lymphocyte count and serum antibody level.
publishDate 2002
dc.date.none.fl_str_mv 2002-03-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2061
10.5433/1679-0359.2002v23n1p15
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2061
identifier_str_mv 10.5433/1679-0359.2002v23n1p15
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2061/1770
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 23 No. 1 (2002); 15-19
Semina: Ciências Agrárias; v. 23 n. 1 (2002); 15-19
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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