Oxidative stress in dogs

Detalhes bibliográficos
Autor(a) principal: Russo, Claudia
Data de Publicação: 2016
Outros Autores: Bracarense, Ana Paula Frederico Rodrigues Loureiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/21723
Resumo: Reactive oxygen species (ROS), also known as free radicals, are generated during cellular respiration. Under normal conditions, the body has the ability to neutralize the effects of free radicals by using its antioxidant defenses. In the case of an imbalance between oxidants and antioxidants, free radical production exceeds the capacity of organic combustion, resulting in oxidative stress. Of all the cellular components compromised by the harmful effects of ROS, the cell membrane is the most severely affected owing to lipid peroxidation, which invariably leads to changes in the membrane structure and permeability. With lipid peroxidation of the cell membrane, some by-products can be detected and measured in tissues, blood, and other bodily fluids. The measurement of biomarkers of oxidative stress is commonly used to quantify lipid peroxidation of the cell membrane in humans, a species in which ROS can be considered as a cause or consequence of oxidative stress-related diseases. In dogs, few studies have demonstrated this correlation. The present review aims to identify current literature knowledge relating to oxidative stress diseases and their detection in dogs.
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spelling Oxidative stress in dogsEstresse oxidativo em cãesOxidative stressLipid peroxidationFree radicalsDogs.Estresse oxidativoLipoperoxidaçãoRadicais livresCães.Reactive oxygen species (ROS), also known as free radicals, are generated during cellular respiration. Under normal conditions, the body has the ability to neutralize the effects of free radicals by using its antioxidant defenses. In the case of an imbalance between oxidants and antioxidants, free radical production exceeds the capacity of organic combustion, resulting in oxidative stress. Of all the cellular components compromised by the harmful effects of ROS, the cell membrane is the most severely affected owing to lipid peroxidation, which invariably leads to changes in the membrane structure and permeability. With lipid peroxidation of the cell membrane, some by-products can be detected and measured in tissues, blood, and other bodily fluids. The measurement of biomarkers of oxidative stress is commonly used to quantify lipid peroxidation of the cell membrane in humans, a species in which ROS can be considered as a cause or consequence of oxidative stress-related diseases. In dogs, few studies have demonstrated this correlation. The present review aims to identify current literature knowledge relating to oxidative stress diseases and their detection in dogs.Nos processos decorrentes da respiração celular, são gerados produtos denominados espécimes reativos de oxigênio (EROS), conhecidos também como radicais livres. Em condições normais, o organismo possui capacidade de neutralizar os efeitos dos radicais livres utilizando suas defesas antioxidantes. Em situações de desequilíbrio entre agentes oxidantes e antioxidantes, a produção de radicais livres excede a capacidade orgânica de neutralização, resultando na condição conhecida como estresse oxidativo. Dentre todos os componentes celulares atingidos pelos efeitos nocivos dos EROS, as membranas celulares são as estruturas mais severamente acometidas, devido à peroxidação lipídica, que leva, invariavelmente, a alterações estruturais e também na sua permeabilidade. Na peroxidação lipídica da membrana celular, alguns subprodutos podem ser detectados e mensurados nos tecidos, sangue e outros fluidos corpóreos. A mensuração de biomarcadores de estresse oxidativo é habitualmente utilizada para quantificar a lipoperoxidação da membrana celular em humanos, espécie onde as EROS podem ser consideradas como causa ou consequência de doenças relacionadas ao estresse oxidativo. Nos cães, alguns poucos estudos demonstram essa correlação. A presente revisão tem como principal objetivo verificar na literatura, onde se encontra atualmente o conhecimento relacionando o estresse oxidativo às doenças em cães bem como as possíveis formas de detecção de biomarcadores na espécie canina.UEL2016-06-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de Literaturaapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2172310.5433/1679-0359.2016v37n3p1431Semina: Ciências Agrárias; Vol. 37 No. 3 (2016); 1431-1440Semina: Ciências Agrárias; v. 37 n. 3 (2016); 1431-14401679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/21723/19031http://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessRusso, ClaudiaBracarense, Ana Paula Frederico Rodrigues Loureiro2022-12-01T15:50:31Zoai:ojs.pkp.sfu.ca:article/21723Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2022-12-01T15:50:31Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Oxidative stress in dogs
Estresse oxidativo em cães
title Oxidative stress in dogs
spellingShingle Oxidative stress in dogs
Russo, Claudia
Oxidative stress
Lipid peroxidation
Free radicals
Dogs.
Estresse oxidativo
Lipoperoxidação
Radicais livres
Cães.
title_short Oxidative stress in dogs
title_full Oxidative stress in dogs
title_fullStr Oxidative stress in dogs
title_full_unstemmed Oxidative stress in dogs
title_sort Oxidative stress in dogs
author Russo, Claudia
author_facet Russo, Claudia
Bracarense, Ana Paula Frederico Rodrigues Loureiro
author_role author
author2 Bracarense, Ana Paula Frederico Rodrigues Loureiro
author2_role author
dc.contributor.author.fl_str_mv Russo, Claudia
Bracarense, Ana Paula Frederico Rodrigues Loureiro
dc.subject.por.fl_str_mv Oxidative stress
Lipid peroxidation
Free radicals
Dogs.
Estresse oxidativo
Lipoperoxidação
Radicais livres
Cães.
topic Oxidative stress
Lipid peroxidation
Free radicals
Dogs.
Estresse oxidativo
Lipoperoxidação
Radicais livres
Cães.
description Reactive oxygen species (ROS), also known as free radicals, are generated during cellular respiration. Under normal conditions, the body has the ability to neutralize the effects of free radicals by using its antioxidant defenses. In the case of an imbalance between oxidants and antioxidants, free radical production exceeds the capacity of organic combustion, resulting in oxidative stress. Of all the cellular components compromised by the harmful effects of ROS, the cell membrane is the most severely affected owing to lipid peroxidation, which invariably leads to changes in the membrane structure and permeability. With lipid peroxidation of the cell membrane, some by-products can be detected and measured in tissues, blood, and other bodily fluids. The measurement of biomarkers of oxidative stress is commonly used to quantify lipid peroxidation of the cell membrane in humans, a species in which ROS can be considered as a cause or consequence of oxidative stress-related diseases. In dogs, few studies have demonstrated this correlation. The present review aims to identify current literature knowledge relating to oxidative stress diseases and their detection in dogs.
publishDate 2016
dc.date.none.fl_str_mv 2016-06-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de Literatura
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/21723
10.5433/1679-0359.2016v37n3p1431
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/21723
identifier_str_mv 10.5433/1679-0359.2016v37n3p1431
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/21723/19031
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 37 No. 3 (2016); 1431-1440
Semina: Ciências Agrárias; v. 37 n. 3 (2016); 1431-1440
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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