Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine

Detalhes bibliográficos
Autor(a) principal: Mattos Junior, Ewaldo de
Data de Publicação: 2009
Outros Autores: Santos, Gustavo José von Glehn dos, Russo, Claudia, Saut, João Paulo Elsen, Headley, Selwyn Arlinton
Tipo de documento: Artigo
Idioma: por
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2598
Resumo: The objective of this study was to compare the influence of butorphanol and phetidine as part of the preanesthetic medication, in 20 healthy dogs submitted to experimental orthopedic surgery. Dogs were randomly allocated in two groups: GI, acepromazine and butorphanol (0,05 mg.kg 1 and 0,4 mg.kg 1, respectively, i.m.) and, GII, acepromazine and phetidine (0,05 mg.kg 1and 4 mg.kg 1, respectively, i.m.). Anesthesia was induced by administration of propofol (5 mg.kg 1) and maintained by the use of sevoflurane delivered in a 100% oxygen circuit. Plasma concentrations of cortisol and glucose were measured during several surgical procedures: T0, before preanesthetic medication; T1, 20 minutes after preanesthetic medication; T2, at skin incision; T3, at periostal stimulation; and, T4, at skin suture. Concentrations of plasma glucose were not significantly different between the surgical procedures and between the two groups evaluated. Concentrations of plasma cortisol were significantly higher in dogs administered with butorphanol between the surgical procedures of T0 and T3, compared with values for dogs administered with phetidine. These results suggest that phetidine is more adequate to control plasma cortisol in dogs submitted to orthopedic surgery than anesthesia with sevoflurane.
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spelling Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidineAvaliação dos níveis de cortisol e glicemia em cães anestesiados pelo sevofluorano, pré-medicados com butorfanol ou meperidinaAnesthesiaOpioidsNeuroendocrine stressCanine.AnestesiaOpióidesEstresse neuroendócrinoCaninos.The objective of this study was to compare the influence of butorphanol and phetidine as part of the preanesthetic medication, in 20 healthy dogs submitted to experimental orthopedic surgery. Dogs were randomly allocated in two groups: GI, acepromazine and butorphanol (0,05 mg.kg 1 and 0,4 mg.kg 1, respectively, i.m.) and, GII, acepromazine and phetidine (0,05 mg.kg 1and 4 mg.kg 1, respectively, i.m.). Anesthesia was induced by administration of propofol (5 mg.kg 1) and maintained by the use of sevoflurane delivered in a 100% oxygen circuit. Plasma concentrations of cortisol and glucose were measured during several surgical procedures: T0, before preanesthetic medication; T1, 20 minutes after preanesthetic medication; T2, at skin incision; T3, at periostal stimulation; and, T4, at skin suture. Concentrations of plasma glucose were not significantly different between the surgical procedures and between the two groups evaluated. Concentrations of plasma cortisol were significantly higher in dogs administered with butorphanol between the surgical procedures of T0 and T3, compared with values for dogs administered with phetidine. These results suggest that phetidine is more adequate to control plasma cortisol in dogs submitted to orthopedic surgery than anesthesia with sevoflurane.O objetivo deste estudo foi comparar a influência do butorfanol ou meperidina como medicação préanestesica nos níveis de cortisol e glicemia em vinte cães submetidos a cirurgia ortopédica experimental. Os cães foram distribuídos em grupos: GI recebeu acepromazina e butorfanol (0,05 mg.kg 1 e 0,4 mg.kg 1 respectivamente, i.m.) e GII, acepromazina e meperidina (0,05 mg.kg 1 e 4 mg.kg 1 respectivamente, i.m.). A indução anestésica constou de propofol (5 mg.kg 1) e para a manutenção sevofluorano em 100% de oxigênio. A concentração plasmátca de cortisol e glicose foram mensuradas no momentos: T0 antes da medicação pré-anestésica; T1 – vinte minutos após a medicação pré-anestésica; T2 – incisão de pele; T3 – estimulação periosteal e T4 – sutura de pele. Não houve diferença entre os momentos e grupos na dosagem de glicose. A concentração plasmatica de cortisol foi significativamente maior nos cães que receberam butorfanol entre T0 e T3, comparado com o grupo que recebeu meperidina. Esses resultados sugerem que a meperidina promove maior controle da dosagem de cortisol em cães submetidos a cirurgia ortopédica e anestesiados com sevofluorano.UEL2009-07-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/259810.5433/1679-0359.2009v30n2p425Semina: Ciências Agrárias; Vol. 30 No. 2 (2009); 425-434Semina: Ciências Agrárias; v. 30 n. 2 (2009); 425-4341679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2598/2255Mattos Junior, Ewaldo deSantos, Gustavo José von Glehn dosRusso, ClaudiaSaut, João Paulo ElsenHeadley, Selwyn Arlintoninfo:eu-repo/semantics/openAccess2015-11-19T18:38:36Zoai:ojs.pkp.sfu.ca:article/2598Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2015-11-19T18:38:36Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
Avaliação dos níveis de cortisol e glicemia em cães anestesiados pelo sevofluorano, pré-medicados com butorfanol ou meperidina
title Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
spellingShingle Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
Mattos Junior, Ewaldo de
Anesthesia
Opioids
Neuroendocrine stress
Canine.
Anestesia
Opióides
Estresse neuroendócrino
Caninos.
title_short Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
title_full Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
title_fullStr Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
title_full_unstemmed Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
title_sort Evaluation of cortisol and glycemia levels of dogs anesthetized with sevoflurane and premedicated with either butorphanol or phetidine
author Mattos Junior, Ewaldo de
author_facet Mattos Junior, Ewaldo de
Santos, Gustavo José von Glehn dos
Russo, Claudia
Saut, João Paulo Elsen
Headley, Selwyn Arlinton
author_role author
author2 Santos, Gustavo José von Glehn dos
Russo, Claudia
Saut, João Paulo Elsen
Headley, Selwyn Arlinton
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Mattos Junior, Ewaldo de
Santos, Gustavo José von Glehn dos
Russo, Claudia
Saut, João Paulo Elsen
Headley, Selwyn Arlinton
dc.subject.por.fl_str_mv Anesthesia
Opioids
Neuroendocrine stress
Canine.
Anestesia
Opióides
Estresse neuroendócrino
Caninos.
topic Anesthesia
Opioids
Neuroendocrine stress
Canine.
Anestesia
Opióides
Estresse neuroendócrino
Caninos.
description The objective of this study was to compare the influence of butorphanol and phetidine as part of the preanesthetic medication, in 20 healthy dogs submitted to experimental orthopedic surgery. Dogs were randomly allocated in two groups: GI, acepromazine and butorphanol (0,05 mg.kg 1 and 0,4 mg.kg 1, respectively, i.m.) and, GII, acepromazine and phetidine (0,05 mg.kg 1and 4 mg.kg 1, respectively, i.m.). Anesthesia was induced by administration of propofol (5 mg.kg 1) and maintained by the use of sevoflurane delivered in a 100% oxygen circuit. Plasma concentrations of cortisol and glucose were measured during several surgical procedures: T0, before preanesthetic medication; T1, 20 minutes after preanesthetic medication; T2, at skin incision; T3, at periostal stimulation; and, T4, at skin suture. Concentrations of plasma glucose were not significantly different between the surgical procedures and between the two groups evaluated. Concentrations of plasma cortisol were significantly higher in dogs administered with butorphanol between the surgical procedures of T0 and T3, compared with values for dogs administered with phetidine. These results suggest that phetidine is more adequate to control plasma cortisol in dogs submitted to orthopedic surgery than anesthesia with sevoflurane.
publishDate 2009
dc.date.none.fl_str_mv 2009-07-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2598
10.5433/1679-0359.2009v30n2p425
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2598
identifier_str_mv 10.5433/1679-0359.2009v30n2p425
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2598/2255
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 30 No. 2 (2009); 425-434
Semina: Ciências Agrárias; v. 30 n. 2 (2009); 425-434
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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