Influence of induced inflamation with BCG on the regression of Ehrlich tumour
Autor(a) principal: | |
---|---|
Data de Publicação: | 1994 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Semina. Ciências Agrárias (Online) |
DOI: | 10.5433/1679-0359.1994v15n1p8 |
Texto Completo: | https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372 |
Resumo: | It has been analized the influence of experimentally induced inflamation with BCG on the regression of the solid Ehrlich tumour. The experimental model consisted of the administration of BCG intralesionally. The animals received 0,05ml of a suspension containing 2,5 x 106 tumor cells in the footpad. Histologic changes have been demostrated in the development of the tumour at several times after the inoculation of BCG. Alterations in tumour size have also been studied. Estatistic analysis (Student T-test) has not demonstrated significant levels (5%). The growth of the tumour has re-established accompanying the evolution of the process. This fact suggests that although BCG interferes with tumour's growth it was not able to bring about complete destruction of the neoplasia. |
id |
UEL-11_806aaa2dfe9ea24bce2cf959fb060418 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/4372 |
network_acronym_str |
UEL-11 |
network_name_str |
Semina. Ciências Agrárias (Online) |
spelling |
Influence of induced inflamation with BCG on the regression of Ehrlich tumourInfluência do processo inflamatório induzido pelo BCG na evolução do tumor de EhrlichInflammatioNeoplasiaEhrlichTumourBCG.InflamaçãoNeoplasiaTumor de EhrlichBCG. It has been analized the influence of experimentally induced inflamation with BCG on the regression of the solid Ehrlich tumour. The experimental model consisted of the administration of BCG intralesionally. The animals received 0,05ml of a suspension containing 2,5 x 106 tumor cells in the footpad. Histologic changes have been demostrated in the development of the tumour at several times after the inoculation of BCG. Alterations in tumour size have also been studied. Estatistic analysis (Student T-test) has not demonstrated significant levels (5%). The growth of the tumour has re-established accompanying the evolution of the process. This fact suggests that although BCG interferes with tumour's growth it was not able to bring about complete destruction of the neoplasia. Analisou-se a influência do processo inflamatório induzido experimentalmente pela inoculação do BCG na regressão do tumor de Ehrlich na forma sólida. O modelo experimental estabelecido consistiu na inoculação do BCG por via intralesional em coxim plantar de camundongos. O tumor foi induzido pela inoculação de 0,05ml de suspensão contendo aproximadamente 2,5 x 166 células tumorais no coxim plantar direito. Demonstrou-se que nos tempos imediatos à administração do BCG ocorreram alterações no desenvolvimento da massa tumoral detectadas tanto através da mensuração paquimétrica do diâmetro do coxim plantar como através da histopatologia. Contudo, não se observou significância a nível de 5% quando analisados pelo teste T de Student. Com a evolução do processo ocorreu um restabelecimento tumoral, indicando que apesar de interferir com o crescimento e evolução da neoplasia, o tratamento com o BCG intralesional não promoveu a regressão total do tumor. UEL1994-01-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/437210.5433/1679-0359.1994v15n1p8Semina: Ciências Agrárias; Vol. 15 No. 1 (1994); 8-13Semina: Ciências Agrárias; v. 15 n. 1 (1994); 8-131679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372/4492Bracarense, Ana Paula Frederico Rodrigues LoureiroSinhorini, Idêrcio Luizinfo:eu-repo/semantics/openAccess2010-04-23T18:27:27Zoai:ojs.pkp.sfu.ca:article/4372Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2010-04-23T18:27:27Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false |
dc.title.none.fl_str_mv |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour Influência do processo inflamatório induzido pelo BCG na evolução do tumor de Ehrlich |
title |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour |
spellingShingle |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour Influence of induced inflamation with BCG on the regression of Ehrlich tumour Bracarense, Ana Paula Frederico Rodrigues Loureiro Inflammatio Neoplasia Ehrlich Tumour BCG. Inflamação Neoplasia Tumor de Ehrlich BCG. Bracarense, Ana Paula Frederico Rodrigues Loureiro Inflammatio Neoplasia Ehrlich Tumour BCG. Inflamação Neoplasia Tumor de Ehrlich BCG. |
title_short |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour |
title_full |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour |
title_fullStr |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour Influence of induced inflamation with BCG on the regression of Ehrlich tumour |
title_full_unstemmed |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour Influence of induced inflamation with BCG on the regression of Ehrlich tumour |
title_sort |
Influence of induced inflamation with BCG on the regression of Ehrlich tumour |
author |
Bracarense, Ana Paula Frederico Rodrigues Loureiro |
author_facet |
Bracarense, Ana Paula Frederico Rodrigues Loureiro Bracarense, Ana Paula Frederico Rodrigues Loureiro Sinhorini, Idêrcio Luiz Sinhorini, Idêrcio Luiz |
author_role |
author |
author2 |
Sinhorini, Idêrcio Luiz |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Bracarense, Ana Paula Frederico Rodrigues Loureiro Sinhorini, Idêrcio Luiz |
dc.subject.por.fl_str_mv |
Inflammatio Neoplasia Ehrlich Tumour BCG. Inflamação Neoplasia Tumor de Ehrlich BCG. |
topic |
Inflammatio Neoplasia Ehrlich Tumour BCG. Inflamação Neoplasia Tumor de Ehrlich BCG. |
description |
It has been analized the influence of experimentally induced inflamation with BCG on the regression of the solid Ehrlich tumour. The experimental model consisted of the administration of BCG intralesionally. The animals received 0,05ml of a suspension containing 2,5 x 106 tumor cells in the footpad. Histologic changes have been demostrated in the development of the tumour at several times after the inoculation of BCG. Alterations in tumour size have also been studied. Estatistic analysis (Student T-test) has not demonstrated significant levels (5%). The growth of the tumour has re-established accompanying the evolution of the process. This fact suggests that although BCG interferes with tumour's growth it was not able to bring about complete destruction of the neoplasia. |
publishDate |
1994 |
dc.date.none.fl_str_mv |
1994-01-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372 10.5433/1679-0359.1994v15n1p8 |
url |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372 |
identifier_str_mv |
10.5433/1679-0359.1994v15n1p8 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372/4492 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UEL |
publisher.none.fl_str_mv |
UEL |
dc.source.none.fl_str_mv |
Semina: Ciências Agrárias; Vol. 15 No. 1 (1994); 8-13 Semina: Ciências Agrárias; v. 15 n. 1 (1994); 8-13 1679-0359 1676-546X reponame:Semina. Ciências Agrárias (Online) instname:Universidade Estadual de Londrina (UEL) instacron:UEL |
instname_str |
Universidade Estadual de Londrina (UEL) |
instacron_str |
UEL |
institution |
UEL |
reponame_str |
Semina. Ciências Agrárias (Online) |
collection |
Semina. Ciências Agrárias (Online) |
repository.name.fl_str_mv |
Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL) |
repository.mail.fl_str_mv |
semina.agrarias@uel.br |
_version_ |
1822182790784876544 |
dc.identifier.doi.none.fl_str_mv |
10.5433/1679-0359.1994v15n1p8 |