Influence of induced inflamation with BCG on the regression of Ehrlich tumour

Detalhes bibliográficos
Autor(a) principal: Bracarense, Ana Paula Frederico Rodrigues Loureiro
Data de Publicação: 1994
Outros Autores: Sinhorini, Idêrcio Luiz
Tipo de documento: Artigo
Idioma: por
Título da fonte: Semina. Ciências Agrárias (Online)
DOI: 10.5433/1679-0359.1994v15n1p8
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372
Resumo: It has been analized the influence of experimentally induced inflamation with BCG on the regression of the solid Ehrlich tumour. The experimental model consisted of the administration of BCG intralesionally. The animals received 0,05ml of a suspension containing 2,5 x 106 tumor cells in the footpad. Histologic changes have been demostrated in the development of the tumour at several times after the inoculation of BCG. Alterations in tumour size have also been studied. Estatistic analysis (Student T-test) has not demonstrated significant levels (5%). The growth of the tumour has re-established accompanying the evolution of the process. This fact suggests that although BCG interferes with tumour's growth it was not able to bring about complete destruction of the neoplasia.  
id UEL-11_806aaa2dfe9ea24bce2cf959fb060418
oai_identifier_str oai:ojs.pkp.sfu.ca:article/4372
network_acronym_str UEL-11
network_name_str Semina. Ciências Agrárias (Online)
spelling Influence of induced inflamation with BCG on the regression of Ehrlich tumourInfluência do processo inflamatório induzido pelo BCG na evolução do tumor de EhrlichInflammatioNeoplasiaEhrlichTumourBCG.InflamaçãoNeoplasiaTumor de EhrlichBCG. It has been analized the influence of experimentally induced inflamation with BCG on the regression of the solid Ehrlich tumour. The experimental model consisted of the administration of BCG intralesionally. The animals received 0,05ml of a suspension containing 2,5 x 106 tumor cells in the footpad. Histologic changes have been demostrated in the development of the tumour at several times after the inoculation of BCG. Alterations in tumour size have also been studied. Estatistic analysis (Student T-test) has not demonstrated significant levels (5%). The growth of the tumour has re-established accompanying the evolution of the process. This fact suggests that although BCG interferes with tumour's growth it was not able to bring about complete destruction of the neoplasia.   Analisou-se a influência do processo inflamatório induzido experimentalmente pela inoculação do BCG na regressão do tumor de Ehrlich na forma sólida. O modelo experimental estabelecido consistiu na inoculação do BCG por via intralesional em coxim plantar de camundongos. O tumor foi induzido pela inoculação de 0,05ml de suspensão contendo aproximadamente 2,5 x 166 células tumorais no coxim plantar direito. Demonstrou-se que nos tempos imediatos à administração do BCG ocorreram alterações no desenvolvimento da massa tumoral detectadas tanto através da mensuração paquimétrica do diâmetro do coxim plantar como através da histopatologia. Contudo, não se observou significância a nível de 5% quando analisados pelo teste T de Student. Com a evolução do processo ocorreu um restabelecimento tumoral, indicando que apesar de interferir com o crescimento e evolução da neoplasia, o tratamento com o BCG intralesional não promoveu a regressão total do tumor.    UEL1994-01-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/437210.5433/1679-0359.1994v15n1p8Semina: Ciências Agrárias; Vol. 15 No. 1 (1994); 8-13Semina: Ciências Agrárias; v. 15 n. 1 (1994); 8-131679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372/4492Bracarense, Ana Paula Frederico Rodrigues LoureiroSinhorini, Idêrcio Luizinfo:eu-repo/semantics/openAccess2010-04-23T18:27:27Zoai:ojs.pkp.sfu.ca:article/4372Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2010-04-23T18:27:27Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Influence of induced inflamation with BCG on the regression of Ehrlich tumour
Influência do processo inflamatório induzido pelo BCG na evolução do tumor de Ehrlich
title Influence of induced inflamation with BCG on the regression of Ehrlich tumour
spellingShingle Influence of induced inflamation with BCG on the regression of Ehrlich tumour
Influence of induced inflamation with BCG on the regression of Ehrlich tumour
Bracarense, Ana Paula Frederico Rodrigues Loureiro
Inflammatio
Neoplasia
Ehrlich
Tumour
BCG.
Inflamação
Neoplasia
Tumor de Ehrlich
BCG.
Bracarense, Ana Paula Frederico Rodrigues Loureiro
Inflammatio
Neoplasia
Ehrlich
Tumour
BCG.
Inflamação
Neoplasia
Tumor de Ehrlich
BCG.
title_short Influence of induced inflamation with BCG on the regression of Ehrlich tumour
title_full Influence of induced inflamation with BCG on the regression of Ehrlich tumour
title_fullStr Influence of induced inflamation with BCG on the regression of Ehrlich tumour
Influence of induced inflamation with BCG on the regression of Ehrlich tumour
title_full_unstemmed Influence of induced inflamation with BCG on the regression of Ehrlich tumour
Influence of induced inflamation with BCG on the regression of Ehrlich tumour
title_sort Influence of induced inflamation with BCG on the regression of Ehrlich tumour
author Bracarense, Ana Paula Frederico Rodrigues Loureiro
author_facet Bracarense, Ana Paula Frederico Rodrigues Loureiro
Bracarense, Ana Paula Frederico Rodrigues Loureiro
Sinhorini, Idêrcio Luiz
Sinhorini, Idêrcio Luiz
author_role author
author2 Sinhorini, Idêrcio Luiz
author2_role author
dc.contributor.author.fl_str_mv Bracarense, Ana Paula Frederico Rodrigues Loureiro
Sinhorini, Idêrcio Luiz
dc.subject.por.fl_str_mv Inflammatio
Neoplasia
Ehrlich
Tumour
BCG.
Inflamação
Neoplasia
Tumor de Ehrlich
BCG.
topic Inflammatio
Neoplasia
Ehrlich
Tumour
BCG.
Inflamação
Neoplasia
Tumor de Ehrlich
BCG.
description It has been analized the influence of experimentally induced inflamation with BCG on the regression of the solid Ehrlich tumour. The experimental model consisted of the administration of BCG intralesionally. The animals received 0,05ml of a suspension containing 2,5 x 106 tumor cells in the footpad. Histologic changes have been demostrated in the development of the tumour at several times after the inoculation of BCG. Alterations in tumour size have also been studied. Estatistic analysis (Student T-test) has not demonstrated significant levels (5%). The growth of the tumour has re-established accompanying the evolution of the process. This fact suggests that although BCG interferes with tumour's growth it was not able to bring about complete destruction of the neoplasia.  
publishDate 1994
dc.date.none.fl_str_mv 1994-01-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372
10.5433/1679-0359.1994v15n1p8
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372
identifier_str_mv 10.5433/1679-0359.1994v15n1p8
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4372/4492
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 15 No. 1 (1994); 8-13
Semina: Ciências Agrárias; v. 15 n. 1 (1994); 8-13
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
_version_ 1822182790784876544
dc.identifier.doi.none.fl_str_mv 10.5433/1679-0359.1994v15n1p8