Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Semina. Ciências Agrárias (Online) |
Texto Completo: | https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15405 |
Resumo: | Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. Most often, the disease is asymptomatic in dogs due to effectiveness of the immune system. By the way, numerous clinical signs can be triggered, including neuromuscular like ataxia, circling, behavioral changes, seizures, spasms and tremors. The disease usually manifests itself after immune depression, and, for this reason, usually may be associated to immunosuppressive infections, like by distemper virus and Ehrlichia canis. E. canis is an obligatory intracellular rickettsia of mature or immature hematopoietic cells and canine monocytes, and the etiologic agent of Canine Monocytic Ehrlichiosis (CME). Like toxoplasmosis, CME may cause nervous signs as well. This study aims to estimate the occurrence of anti- T. gondii and anti- E. canis antibodies and characterize nervous syndromes in dogs with nervous alterations assisted at a veterinary teaching hospital. From May 2010 to December 2011, dogs with nervous alterations assisted at HOVET-UFMT were submitted to neurological evaluation for determining nervous syndromes. Serum and whole blood samples were collected for performing indirect immunofluorescence test (IFAT) for T. gondii and E. canis and hematological evaluation. Prevalence of 10,3 and 94,8% were observed for T. gondii and E. canis, respectively. The most frequent syndrome was multifocal, occurring in 53,5% of the cases, followed by spinal cord alterations in 22,4%, cerebral alterations in 10,3%, paroxysmal syndrome in 10,3% and neuropathic syndrome in 3,5% of the cases. There was no statistical significance between the variables analyzed (titration to T. gondii, E. canis and nervous syndromes). In conclusion, the occurrence of coinfection with T. gondii and E. canis may contribute to toxoplasmosis clinical manifestation, due to opportunist character of the parasite in order to the establishment of disease. |
id |
UEL-11_fd85e62b2b38600ac4653f7b67645150 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/15405 |
network_acronym_str |
UEL-11 |
network_name_str |
Semina. Ciências Agrárias (Online) |
repository_id_str |
|
spelling |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospitalOcorrência de anticorpos anti-Toxoplasma gondii e Ehrlichia canis em cães com alterações nervosas atendidos em hospital veterinário universitárioToxoplasmosisEhrlichiosisNeurologyNervous syndromes.ToxoplasmoseErliquioseNeurologiaSíndromes nervosas.Doenças Infecciosas de AnimaisToxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. Most often, the disease is asymptomatic in dogs due to effectiveness of the immune system. By the way, numerous clinical signs can be triggered, including neuromuscular like ataxia, circling, behavioral changes, seizures, spasms and tremors. The disease usually manifests itself after immune depression, and, for this reason, usually may be associated to immunosuppressive infections, like by distemper virus and Ehrlichia canis. E. canis is an obligatory intracellular rickettsia of mature or immature hematopoietic cells and canine monocytes, and the etiologic agent of Canine Monocytic Ehrlichiosis (CME). Like toxoplasmosis, CME may cause nervous signs as well. This study aims to estimate the occurrence of anti- T. gondii and anti- E. canis antibodies and characterize nervous syndromes in dogs with nervous alterations assisted at a veterinary teaching hospital. From May 2010 to December 2011, dogs with nervous alterations assisted at HOVET-UFMT were submitted to neurological evaluation for determining nervous syndromes. Serum and whole blood samples were collected for performing indirect immunofluorescence test (IFAT) for T. gondii and E. canis and hematological evaluation. Prevalence of 10,3 and 94,8% were observed for T. gondii and E. canis, respectively. The most frequent syndrome was multifocal, occurring in 53,5% of the cases, followed by spinal cord alterations in 22,4%, cerebral alterations in 10,3%, paroxysmal syndrome in 10,3% and neuropathic syndrome in 3,5% of the cases. There was no statistical significance between the variables analyzed (titration to T. gondii, E. canis and nervous syndromes). In conclusion, the occurrence of coinfection with T. gondii and E. canis may contribute to toxoplasmosis clinical manifestation, due to opportunist character of the parasite in order to the establishment of disease. A toxoplasmose é uma zoonose causada por Toxoplasma gondii. Em cães é na maioria das vezes assintomática em decorrência da efetividade do sistema imunológico. Entretanto, em alguns casos pode desencadear inúmeros sinais clínicos, incluindo comprometimento neuromuscular, sendo os sinais mais descritos ataxia, andar em círculos, alterações de comportamento, convulsões, espasmos e tremores. A toxoplasmose geralmente manifesta-se após imunodepressão e por isso, frequentemente pode estar associada a infecções imunossupressoras como as causadas pelo vírus da cinomose e Ehrlichia canis. E. canis é uma rickettsia intracelular obrigatória de células hematopoiéticas maduras ou imaturas e de monócitos caninos, agente etiológico da Erliquiose Monocítica Canina (EMC). Assim como a toxoplasmose, a EMC também pode ocasionar sinais nervosos. Este estudo tem o objetivo de estimar a prevalência de anticorpos contra T. gondii e E. canis e caracterizar as respectivas síndromes clínicas em cães com sinais nervosos atendidos em um hospital veterinário. Entre maio de 2010 a dezembro de 2011, cães com sinais nervosos atendidos no HOVET-UFMT foram submetidos a exame neurológico para determinação das síndromes nervosas. Amostras de soro e sangue total foram coletadas para realização de reação de imunofluorescência indireta (RIFI) para T. gondii e E. canis e para avaliação hematológica. Observaram-se prevalências de 10,3 e 94,8% para T. gondii e E. canis respectivamente, e a síndrome mais frequente foi a multifocal ocorrendo em 53,5% dos casos, seguido de alterações medulares em 22,4%, alteração cerebral em 10,3%, síndrome paroxística em 10,3% dos casos e síndrome neuropática com 3,5% dos casos. Não houve associação estatística entre as variáveis analisadas (titulação para T. gondii, E. canis e síndromes nervosas). Como conclusão, a ocorrência de coinfecção por T. gondii e E.canis pode contribuir para a manifestação clínica da toxoplasmose, em virtude do caráter oportunista do parasito em relação ao estabelecimento de doença. UEL2014-08-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/1540510.5433/1679-0359.2014v35n4p1913Semina: Ciências Agrárias; Vol. 35 No. 4 (2014); 1913-1922Semina: Ciências Agrárias; v. 35 n. 4 (2014); 1913-19221679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15405/pdf_383Copyright (c) 2014 Semina: Ciências Agráriashttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessGirardi, Angela FerronattoLima, Samara RosolemMelo, Andréia Lima ToméBoa Sorte, Eveline da CruzAlmeida, Arleana do Bom Parto Ferreira deMendonça, Adriane JorgeAguiar, Daniel MouraSousa, Valéria Régia Franco2023-01-16T12:35:03Zoai:ojs.pkp.sfu.ca:article/15405Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2023-01-16T12:35:03Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false |
dc.title.none.fl_str_mv |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital Ocorrência de anticorpos anti-Toxoplasma gondii e Ehrlichia canis em cães com alterações nervosas atendidos em hospital veterinário universitário |
title |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital |
spellingShingle |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital Girardi, Angela Ferronatto Toxoplasmosis Ehrlichiosis Neurology Nervous syndromes. Toxoplasmose Erliquiose Neurologia Síndromes nervosas. Doenças Infecciosas de Animais |
title_short |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital |
title_full |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital |
title_fullStr |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital |
title_full_unstemmed |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital |
title_sort |
Ocurrence of anti-Toxoplasma gondii and Ehrlichia canis antibodies in dogs with nervous alterations assisted at a veterinary teaching hospital |
author |
Girardi, Angela Ferronatto |
author_facet |
Girardi, Angela Ferronatto Lima, Samara Rosolem Melo, Andréia Lima Tomé Boa Sorte, Eveline da Cruz Almeida, Arleana do Bom Parto Ferreira de Mendonça, Adriane Jorge Aguiar, Daniel Moura Sousa, Valéria Régia Franco |
author_role |
author |
author2 |
Lima, Samara Rosolem Melo, Andréia Lima Tomé Boa Sorte, Eveline da Cruz Almeida, Arleana do Bom Parto Ferreira de Mendonça, Adriane Jorge Aguiar, Daniel Moura Sousa, Valéria Régia Franco |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Girardi, Angela Ferronatto Lima, Samara Rosolem Melo, Andréia Lima Tomé Boa Sorte, Eveline da Cruz Almeida, Arleana do Bom Parto Ferreira de Mendonça, Adriane Jorge Aguiar, Daniel Moura Sousa, Valéria Régia Franco |
dc.subject.por.fl_str_mv |
Toxoplasmosis Ehrlichiosis Neurology Nervous syndromes. Toxoplasmose Erliquiose Neurologia Síndromes nervosas. Doenças Infecciosas de Animais |
topic |
Toxoplasmosis Ehrlichiosis Neurology Nervous syndromes. Toxoplasmose Erliquiose Neurologia Síndromes nervosas. Doenças Infecciosas de Animais |
description |
Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. Most often, the disease is asymptomatic in dogs due to effectiveness of the immune system. By the way, numerous clinical signs can be triggered, including neuromuscular like ataxia, circling, behavioral changes, seizures, spasms and tremors. The disease usually manifests itself after immune depression, and, for this reason, usually may be associated to immunosuppressive infections, like by distemper virus and Ehrlichia canis. E. canis is an obligatory intracellular rickettsia of mature or immature hematopoietic cells and canine monocytes, and the etiologic agent of Canine Monocytic Ehrlichiosis (CME). Like toxoplasmosis, CME may cause nervous signs as well. This study aims to estimate the occurrence of anti- T. gondii and anti- E. canis antibodies and characterize nervous syndromes in dogs with nervous alterations assisted at a veterinary teaching hospital. From May 2010 to December 2011, dogs with nervous alterations assisted at HOVET-UFMT were submitted to neurological evaluation for determining nervous syndromes. Serum and whole blood samples were collected for performing indirect immunofluorescence test (IFAT) for T. gondii and E. canis and hematological evaluation. Prevalence of 10,3 and 94,8% were observed for T. gondii and E. canis, respectively. The most frequent syndrome was multifocal, occurring in 53,5% of the cases, followed by spinal cord alterations in 22,4%, cerebral alterations in 10,3%, paroxysmal syndrome in 10,3% and neuropathic syndrome in 3,5% of the cases. There was no statistical significance between the variables analyzed (titration to T. gondii, E. canis and nervous syndromes). In conclusion, the occurrence of coinfection with T. gondii and E. canis may contribute to toxoplasmosis clinical manifestation, due to opportunist character of the parasite in order to the establishment of disease. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-08-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15405 10.5433/1679-0359.2014v35n4p1913 |
url |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15405 |
identifier_str_mv |
10.5433/1679-0359.2014v35n4p1913 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15405/pdf_383 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2014 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2014 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UEL |
publisher.none.fl_str_mv |
UEL |
dc.source.none.fl_str_mv |
Semina: Ciências Agrárias; Vol. 35 No. 4 (2014); 1913-1922 Semina: Ciências Agrárias; v. 35 n. 4 (2014); 1913-1922 1679-0359 1676-546X reponame:Semina. Ciências Agrárias (Online) instname:Universidade Estadual de Londrina (UEL) instacron:UEL |
instname_str |
Universidade Estadual de Londrina (UEL) |
instacron_str |
UEL |
institution |
UEL |
reponame_str |
Semina. Ciências Agrárias (Online) |
collection |
Semina. Ciências Agrárias (Online) |
repository.name.fl_str_mv |
Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL) |
repository.mail.fl_str_mv |
semina.agrarias@uel.br |
_version_ |
1799306070246555648 |