Desenvolvimento de métodos limpos para a extração e determinação de Triclosan e Etilhexilmetoxicinamato

• Autor(a) principal: Silva, Valquíria de Moraes
• Data de Publicação: 2013
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
• Texto Completo: http://repositorio.uem.br:8080/jspui/handle/1/3939
• topic: Cromatografia líquida de alta eficiência (CLAE); Extração em fase sólida; Produtos de higiene pessoal; Brasil.; Ciências Exatas e da Terra; Química

Personal-care products, pharmaceuticals among others products are known as emerging pollutants and have been gaining prominence as the newest environmental contaminants. The concern with these pollutants is justified by the fact that these products contain compounds in their formulation that can accumulate in the environment and be harmful to species that live there, especially because many of the emerging pollutants are known to cause damage to human health. Considering the environmental importance and the large number of products that contain the emerging pollutants in the present work are proposed analytical methods for extraction, separation, identification and chromatographic determination of compounds Triclosan (TCS), a widely used bactericide, and EthylhexylMethoxycinnamate (EHMC), a compound used as UV-filter. All the developed methods sought to obey the principles of Green Chemistry, which prioritizes the development and implementation of methodologies that reduce or eliminate the use of toxic organic solvents or generation of substances harmful to human health and to the environment. For solid phase extraction was used cartridge containing C18 stationary phase and as eluant a mixture of ethanol: methanol (90:10, v/v), reaching recovery rates of 80.0 and 83.0% for TCS and EHMC, respectively. For the determination step was used high performance liquid chromatography (HPLC) with a C18 column and as mobile phase a mixture of ethanol: 0.01% phosphoric acid solution (75:25, v/v). The developed chromatographic method is inexpensive and allows the analysis of compounds in 15 min with limits of detection and quantitation of 0,021 and 0,091 mg L-1 to TCS and of 0,0011 and 0.0066 mg L-1 for EHMC, respectively; which able the method to be applied to water samples analysis. When the method was applied to analysis in urban wastewater of Maringa, PR, it was observed that the contaminant TCS was found in the concentration range of 3.40 up to 23.0 μg L-1 in river-water samples and, the pollutant was not found in treated drinking water samples. The UV-filter EHMC was found in the concentration range of 17.0 up to 40,0 μg L-1 in river-water samples and in the concentration of 1.70 μg L-1 in drinking-water samples, indicating that the conventional drinking water treatment is not efficient to eliminates this pollutant.