Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Acta Scientiarum Biological Sciences |
Texto Completo: | http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/3623 |
Resumo: | This work had the purpose of characterizing the development of female Wistar rats subjected to food restriction since birth, investigating some quantitative and functional changes resulting from this deficiency. Food restriction was imposed through duplication of the litter size (restriction group, 12 pups) relative to the control litter (control group, six pups) during lactation, and through reduction in 50% of the food supplied from weaning to 90 days of age. The female rats of the restriction group, when compared to the controls, had smaller linear and ponderal growth, lower organ weight and poorly developed abdominal fat deposits, and delayed vaginal opening. On the other hand, their growth continued during the 90-day period. After mating, the control female rats had large litters, while none of the rats from the restriction group got pregnant. It was concluded that food restriction during and after lactation interfered negatively on the body development of the rats, delayed the onset of puberty as indicated by the vaginal opening, impaired the growth of the internal organs and the storage of fat, and prevented conception. |
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Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623Crescimento e parâmetros reprodutivos de ratas Wistar, em restrição alimentar desde o nascimento - DOI: 10.4025/actascibiolsci.v30i2.3623restrição alimentarfêmeasratos Wistarreproduçãocrescimento2.06.00.00-3 MorfologiaThis work had the purpose of characterizing the development of female Wistar rats subjected to food restriction since birth, investigating some quantitative and functional changes resulting from this deficiency. Food restriction was imposed through duplication of the litter size (restriction group, 12 pups) relative to the control litter (control group, six pups) during lactation, and through reduction in 50% of the food supplied from weaning to 90 days of age. The female rats of the restriction group, when compared to the controls, had smaller linear and ponderal growth, lower organ weight and poorly developed abdominal fat deposits, and delayed vaginal opening. On the other hand, their growth continued during the 90-day period. After mating, the control female rats had large litters, while none of the rats from the restriction group got pregnant. It was concluded that food restriction during and after lactation interfered negatively on the body development of the rats, delayed the onset of puberty as indicated by the vaginal opening, impaired the growth of the internal organs and the storage of fat, and prevented conception.Este trabalho teve como objetivo caracterizar o desenvolvimento de ratas Wistar, submetidas à restrição alimentar desde o nascimento, investigando algumas alterações quantitativas e funcionais resultantes desta deficiência. A restrição alimentar foi imposta por duplicação do tamanho da ninhada experimental (grupo-restrição, 12 filhotes) em relação à ninhada-controle (grupo-controle, seis filhotes) durante a lactação, e por redução de 50% no alimento ofertado desde o desmame até os 90 dias de idade. As ratas do grupo-restrição, comparadas às do grupo-controle, apresentaram crescimento ponderal e linear inferior, menor peso de órgãos e depósitos abdominais de gordura pouco desenvolvidos e retardo na idade da abertura vaginal. Por outro lado, seu crescimento prosseguiu por todo o período de 90 dias. Após o cruzamento, as ratas do grupo-controle tiveram ninhadas numerosas, enquanto nenhuma das ratas do grupo-restrição emprenhou. Concluiu-se que a restrição alimentar, durante e após a lactação, interferiu negativamente no desenvolvimento corporal das ratas, retardou o início da puberdade, indicado pela idade da abertura vaginal, comprometeu o crescimento dos órgãos internos e a deposição de gordura, e impediu a concepção.Universidade Estadual De Maringá2008-05-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/362310.4025/actascibiolsci.v30i2.3623Acta Scientiarum. Biological Sciences; Vol 30 No 2 (2008); 197-204Acta Scientiarum. Biological Sciences; v. 30 n. 2 (2008); 197-2041807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/3623/2542Mazeti, Camila MontoroFurlan, Maria Montserrat Dias Pedrosainfo:eu-repo/semantics/openAccess2022-11-23T17:33:36Zoai:periodicos.uem.br/ojs:article/3623Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2022-11-23T17:33:36Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false |
dc.title.none.fl_str_mv |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 Crescimento e parâmetros reprodutivos de ratas Wistar, em restrição alimentar desde o nascimento - DOI: 10.4025/actascibiolsci.v30i2.3623 |
title |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 |
spellingShingle |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 Mazeti, Camila Montoro restrição alimentar fêmeas ratos Wistar reprodução crescimento 2.06.00.00-3 Morfologia |
title_short |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 |
title_full |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 |
title_fullStr |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 |
title_full_unstemmed |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 |
title_sort |
Growth and reproductive parameters of female Wistar rats under food restriction since birth - DOI: 10.4025/actascibiolsci.v30i3.3623 |
author |
Mazeti, Camila Montoro |
author_facet |
Mazeti, Camila Montoro Furlan, Maria Montserrat Dias Pedrosa |
author_role |
author |
author2 |
Furlan, Maria Montserrat Dias Pedrosa |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Mazeti, Camila Montoro Furlan, Maria Montserrat Dias Pedrosa |
dc.subject.por.fl_str_mv |
restrição alimentar fêmeas ratos Wistar reprodução crescimento 2.06.00.00-3 Morfologia |
topic |
restrição alimentar fêmeas ratos Wistar reprodução crescimento 2.06.00.00-3 Morfologia |
description |
This work had the purpose of characterizing the development of female Wistar rats subjected to food restriction since birth, investigating some quantitative and functional changes resulting from this deficiency. Food restriction was imposed through duplication of the litter size (restriction group, 12 pups) relative to the control litter (control group, six pups) during lactation, and through reduction in 50% of the food supplied from weaning to 90 days of age. The female rats of the restriction group, when compared to the controls, had smaller linear and ponderal growth, lower organ weight and poorly developed abdominal fat deposits, and delayed vaginal opening. On the other hand, their growth continued during the 90-day period. After mating, the control female rats had large litters, while none of the rats from the restriction group got pregnant. It was concluded that food restriction during and after lactation interfered negatively on the body development of the rats, delayed the onset of puberty as indicated by the vaginal opening, impaired the growth of the internal organs and the storage of fat, and prevented conception. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-05-29 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/3623 10.4025/actascibiolsci.v30i2.3623 |
url |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/3623 |
identifier_str_mv |
10.4025/actascibiolsci.v30i2.3623 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/3623/2542 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
dc.source.none.fl_str_mv |
Acta Scientiarum. Biological Sciences; Vol 30 No 2 (2008); 197-204 Acta Scientiarum. Biological Sciences; v. 30 n. 2 (2008); 197-204 1807-863X 1679-9283 reponame:Acta Scientiarum Biological Sciences instname:Universidade Estadual de Maringá (UEM) instacron:UEM |
instname_str |
Universidade Estadual de Maringá (UEM) |
instacron_str |
UEM |
institution |
UEM |
reponame_str |
Acta Scientiarum Biological Sciences |
collection |
Acta Scientiarum Biological Sciences |
repository.name.fl_str_mv |
Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM) |
repository.mail.fl_str_mv |
||actabiol@uem.br |
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1799317393617453056 |