Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats
Autor(a) principal: | |
---|---|
Data de Publicação: | 2019 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Scientiarum Biological Sciences |
Texto Completo: | http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014 |
Resumo: | The steroid hormones are lipids in nature, which play crucial roles in several metabolic and behavioral pathways in mammals. Drug therapy uses sterol hormones for treating some disturbances linked with its deficiency; however, the illicit use of these hormones by amateur and elite athletes to enhance performance or body appearance may lead to several health issues. In this study we evaluated the anxious-like behavior and the long-term memory acquisition of male rats undergoing sedentary life-style or physical effort, with or without anabolic-androgenic steroids (ASC) treatment. The results showed a decrease in anxious-like behavioral levels in rats that received ASC treatment associated or not with physical effort, but this treatment did not affect the acquisition of long-term memory at the dose and experimental model assessed. |
id |
UEM-1_72e3b56cdf5b35594436417e7b7143eb |
---|---|
oai_identifier_str |
oai:periodicos.uem.br/ojs:article/45014 |
network_acronym_str |
UEM-1 |
network_name_str |
Acta Scientiarum Biological Sciences |
repository_id_str |
|
spelling |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in ratsandrogensphysical exercisememoryanxietyFarmacologia de esteroides androgênicosThe steroid hormones are lipids in nature, which play crucial roles in several metabolic and behavioral pathways in mammals. Drug therapy uses sterol hormones for treating some disturbances linked with its deficiency; however, the illicit use of these hormones by amateur and elite athletes to enhance performance or body appearance may lead to several health issues. In this study we evaluated the anxious-like behavior and the long-term memory acquisition of male rats undergoing sedentary life-style or physical effort, with or without anabolic-androgenic steroids (ASC) treatment. The results showed a decrease in anxious-like behavioral levels in rats that received ASC treatment associated or not with physical effort, but this treatment did not affect the acquisition of long-term memory at the dose and experimental model assessed.Universidade Estadual De Maringá2019-07-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionFenomenologiaapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/4501410.4025/actascibiolsci.v41i1.45014Acta Scientiarum. Biological Sciences; Vol 41 (2019): Publicação contínua; e45014Acta Scientiarum. Biological Sciences; v. 41 (2019): Publicação contínua; e450141807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMenghttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/751375147767http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/751375147768http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/751375147769Copyright (c) 2019 Acta Scientiarum. Biological Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, Luís Flávio Souza deStaudt, MiriamMachado, Michel MansurFuentefria, Alexandre Meneghello2022-02-20T21:59:24Zoai:periodicos.uem.br/ojs:article/45014Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2022-02-20T21:59:24Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false |
dc.title.none.fl_str_mv |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats |
title |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats |
spellingShingle |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats Oliveira, Luís Flávio Souza de androgens physical exercise memory anxiety Farmacologia de esteroides androgênicos |
title_short |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats |
title_full |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats |
title_fullStr |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats |
title_full_unstemmed |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats |
title_sort |
Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats |
author |
Oliveira, Luís Flávio Souza de |
author_facet |
Oliveira, Luís Flávio Souza de Staudt, Miriam Machado, Michel Mansur Fuentefria, Alexandre Meneghello |
author_role |
author |
author2 |
Staudt, Miriam Machado, Michel Mansur Fuentefria, Alexandre Meneghello |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Luís Flávio Souza de Staudt, Miriam Machado, Michel Mansur Fuentefria, Alexandre Meneghello |
dc.subject.por.fl_str_mv |
androgens physical exercise memory anxiety Farmacologia de esteroides androgênicos |
topic |
androgens physical exercise memory anxiety Farmacologia de esteroides androgênicos |
description |
The steroid hormones are lipids in nature, which play crucial roles in several metabolic and behavioral pathways in mammals. Drug therapy uses sterol hormones for treating some disturbances linked with its deficiency; however, the illicit use of these hormones by amateur and elite athletes to enhance performance or body appearance may lead to several health issues. In this study we evaluated the anxious-like behavior and the long-term memory acquisition of male rats undergoing sedentary life-style or physical effort, with or without anabolic-androgenic steroids (ASC) treatment. The results showed a decrease in anxious-like behavioral levels in rats that received ASC treatment associated or not with physical effort, but this treatment did not affect the acquisition of long-term memory at the dose and experimental model assessed. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-07-22 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Fenomenologia |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014 10.4025/actascibiolsci.v41i1.45014 |
url |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014 |
identifier_str_mv |
10.4025/actascibiolsci.v41i1.45014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/pdf http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/751375147767 http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/751375147768 http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/45014/751375147769 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2019 Acta Scientiarum. Biological Sciences https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2019 Acta Scientiarum. Biological Sciences https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
dc.source.none.fl_str_mv |
Acta Scientiarum. Biological Sciences; Vol 41 (2019): Publicação contínua; e45014 Acta Scientiarum. Biological Sciences; v. 41 (2019): Publicação contínua; e45014 1807-863X 1679-9283 reponame:Acta Scientiarum Biological Sciences instname:Universidade Estadual de Maringá (UEM) instacron:UEM |
instname_str |
Universidade Estadual de Maringá (UEM) |
instacron_str |
UEM |
institution |
UEM |
reponame_str |
Acta Scientiarum Biological Sciences |
collection |
Acta Scientiarum Biological Sciences |
repository.name.fl_str_mv |
Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM) |
repository.mail.fl_str_mv |
||actabiol@uem.br |
_version_ |
1799317397380792320 |