Metabolic modeling and comparative biochemistry in glyoxylate cycle

Detalhes bibliográficos
Autor(a) principal: Gonçalves, Itamar Luís
Data de Publicação: 2016
Outros Autores: Mielniczki-Pereira, Albanin Aparecida, Piovezan Borges, Ana Claudia, Valduga, Alice Teresa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Scientiarum Biological Sciences
Texto Completo: http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/24597
Resumo: Glyoxylate cycle in fatty acid catabolism enhances net production of oxaloacetate, a substrate for gluconeogenesis, in certain bacteria, invertebrates and oilseed in the growth stage. A theoretical model was developed to calculate ATP amount produced in each step of the catabolic pathway, taking into account the fatty acid’s hydrocarbon chain size. Results showed a decrease in energy efficiency in glyoxylate cycle when compared to animal metabolism. Although the glyoxylate cycle provides evolutionary adaptations, it determines a smaller amount of energy produced per carbon atom when compared to animal catabolism of fatty acids. 
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spelling Metabolic modeling and comparative biochemistry in glyoxylate cyclecatabolismenergy efficiencyacetyl-CoA oxidationBioquímicaGlyoxylate cycle in fatty acid catabolism enhances net production of oxaloacetate, a substrate for gluconeogenesis, in certain bacteria, invertebrates and oilseed in the growth stage. A theoretical model was developed to calculate ATP amount produced in each step of the catabolic pathway, taking into account the fatty acid’s hydrocarbon chain size. Results showed a decrease in energy efficiency in glyoxylate cycle when compared to animal metabolism. Although the glyoxylate cycle provides evolutionary adaptations, it determines a smaller amount of energy produced per carbon atom when compared to animal catabolism of fatty acids. Universidade Estadual De Maringá2016-07-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2459710.4025/actascibiolsci.v38i1.24597Acta Scientiarum. Biological Sciences; Vol 38 No 1 (2016); 1-6Acta Scientiarum. Biological Sciences; v. 38 n. 1 (2016); 1-61807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMenghttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/24597/pdfGonçalves, Itamar LuísMielniczki-Pereira, Albanin AparecidaPiovezan Borges, Ana ClaudiaValduga, Alice Teresainfo:eu-repo/semantics/openAccess2022-02-17T22:01:02Zoai:periodicos.uem.br/ojs:article/24597Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2022-02-17T22:01:02Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv Metabolic modeling and comparative biochemistry in glyoxylate cycle
title Metabolic modeling and comparative biochemistry in glyoxylate cycle
spellingShingle Metabolic modeling and comparative biochemistry in glyoxylate cycle
Gonçalves, Itamar Luís
catabolism
energy efficiency
acetyl-CoA oxidation
Bioquímica
title_short Metabolic modeling and comparative biochemistry in glyoxylate cycle
title_full Metabolic modeling and comparative biochemistry in glyoxylate cycle
title_fullStr Metabolic modeling and comparative biochemistry in glyoxylate cycle
title_full_unstemmed Metabolic modeling and comparative biochemistry in glyoxylate cycle
title_sort Metabolic modeling and comparative biochemistry in glyoxylate cycle
author Gonçalves, Itamar Luís
author_facet Gonçalves, Itamar Luís
Mielniczki-Pereira, Albanin Aparecida
Piovezan Borges, Ana Claudia
Valduga, Alice Teresa
author_role author
author2 Mielniczki-Pereira, Albanin Aparecida
Piovezan Borges, Ana Claudia
Valduga, Alice Teresa
author2_role author
author
author
dc.contributor.author.fl_str_mv Gonçalves, Itamar Luís
Mielniczki-Pereira, Albanin Aparecida
Piovezan Borges, Ana Claudia
Valduga, Alice Teresa
dc.subject.por.fl_str_mv catabolism
energy efficiency
acetyl-CoA oxidation
Bioquímica
topic catabolism
energy efficiency
acetyl-CoA oxidation
Bioquímica
description Glyoxylate cycle in fatty acid catabolism enhances net production of oxaloacetate, a substrate for gluconeogenesis, in certain bacteria, invertebrates and oilseed in the growth stage. A theoretical model was developed to calculate ATP amount produced in each step of the catabolic pathway, taking into account the fatty acid’s hydrocarbon chain size. Results showed a decrease in energy efficiency in glyoxylate cycle when compared to animal metabolism. Although the glyoxylate cycle provides evolutionary adaptations, it determines a smaller amount of energy produced per carbon atom when compared to animal catabolism of fatty acids. 
publishDate 2016
dc.date.none.fl_str_mv 2016-07-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/24597
10.4025/actascibiolsci.v38i1.24597
url http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/24597
identifier_str_mv 10.4025/actascibiolsci.v38i1.24597
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/24597/pdf
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual De Maringá
publisher.none.fl_str_mv Universidade Estadual De Maringá
dc.source.none.fl_str_mv Acta Scientiarum. Biological Sciences; Vol 38 No 1 (2016); 1-6
Acta Scientiarum. Biological Sciences; v. 38 n. 1 (2016); 1-6
1807-863X
1679-9283
reponame:Acta Scientiarum Biological Sciences
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Acta Scientiarum Biological Sciences
collection Acta Scientiarum Biological Sciences
repository.name.fl_str_mv Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||actabiol@uem.br
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