ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care

Detalhes bibliográficos
Autor(a) principal: Machado, Leandro César Teixeira
Data de Publicação: 2022
Outros Autores: Medeiros, Mateus, Stival, Marina Morato, de Sousa Barbalho, Yuri Gustavo, de Lima, Filipe Dinato, de Lima, Luciano Ramos, Silva, Alessandro de Oliveira, da Silva, Izabel Cristina Rodrigues, Funghetto, Silvana Schwerz
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Revista da Educação física/UEM (Online)
Texto Completo: https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/61375
Resumo: Objective: to analyze the potential influences of the R/X genetic polymorphism of the ACTN3 gene and of anthropometric and metabolic characteristics on the functional performance of elderly women assisted in primary health care. Method: One hundred and forty-one elderly women were evaluated in relation to anthropometric, metabolic, functional, clinical, cognitive and demographic characteristics. The frequencies of alleles and genotypes of the ACTN3 gene polymorphism were determined. Results: 141 elderly women (68.30 ± 6.18 years) were evaluated. There were no significant differences (p > 0.05) between the RR and RX/XX genotypes in the functional performance, anthropometric or metabolic characteristics of the elderly women. The duration of the TUG test showed positive correlations with age, body mass index, waist circumference and fat percentage (s = 0.315; p < 0.001; s = 0.238; p = 0.005; s = 0.174; p = 0.039; s = 0.207; p = 0.014) respectively. Negative correlations were observed between the TUG with absolute (s = - 0.314; p < 0.001) and relative (s = - 0.380; p < 0.001) handgrip strength. Conclusion: In our study, no influences of ACTN3 gene polymorphisms were observed on the functional performance of elderly women, which was influenced by other factors.
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spelling ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health carePolimorfismo do gene ACTN3 e os fatores associados ao desempenho funcional de idosas atendidas na atenção primária em saúdeFunctional performanceGenetic variationAgingMuscle strenghDesempenho FuncionalVariação GenéticaEnvelhecimentoForça muscularObjective: to analyze the potential influences of the R/X genetic polymorphism of the ACTN3 gene and of anthropometric and metabolic characteristics on the functional performance of elderly women assisted in primary health care. Method: One hundred and forty-one elderly women were evaluated in relation to anthropometric, metabolic, functional, clinical, cognitive and demographic characteristics. The frequencies of alleles and genotypes of the ACTN3 gene polymorphism were determined. Results: 141 elderly women (68.30 ± 6.18 years) were evaluated. There were no significant differences (p > 0.05) between the RR and RX/XX genotypes in the functional performance, anthropometric or metabolic characteristics of the elderly women. The duration of the TUG test showed positive correlations with age, body mass index, waist circumference and fat percentage (s = 0.315; p < 0.001; s = 0.238; p = 0.005; s = 0.174; p = 0.039; s = 0.207; p = 0.014) respectively. Negative correlations were observed between the TUG with absolute (s = - 0.314; p < 0.001) and relative (s = - 0.380; p < 0.001) handgrip strength. Conclusion: In our study, no influences of ACTN3 gene polymorphisms were observed on the functional performance of elderly women, which was influenced by other factors.Objetivo: analisar as potenciais influências do polimorfismo genético R/X do gene ACTN3 e das características antropométricas e metabólicas no desempenho funcional de mulheres idosas atendidas na atenção primária em saúde. Método: Cento e quarenta e uma idosas foram avaliadas em relação as características antropométricas, metabólicas, funcionais, aspectos clínicos, cognitivos e demográficos. Foram determinadas as frequências de alelos e genótipos do polimorfismo do gene ACTN3. Resultados: 141 idosas (68,30 ± 6,18 anos) foram avaliadas. Não foram observadas diferenças significativas (p > 0,05) entre os genótipos RR e RX/XX no desempenho funcional, características antropométricas ou metabólicas das idosas. O tempo de realização do TUG apresentou correlações positivas com idade, índice de massa corporal, circunferência da cintura e percentual de gordura (s = 0,315; p < 0,001; s = 0,238; p = 0,005; s = 0,174; p = 0,039; s = 0,207; p = 0,014) respectivamente. Correlações negativas foram observadas entre o TUG com força de preensão manual absoluta (s = - 0,314; p < 0,001) e relativa (s = - 0,380; p < 0,001). Conclusão: Em nosso estudo, não foram observadas influências dos polimorfismos do gene ACTN3 no desempenho funcional das idosas, sendo este, influenciado por outros fatores.Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil2022-09-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/6137510.4025/jphyseduc.v33i1.3351Journal of Physical Education; Vol 33 No 1 (2022): Journal of Physical Education; e-3351Journal of Physical Education; Vol. 33 Núm. 1 (2022): Journal of Physical Education; e-3351Journal of Physical Education; v. 33 n. 1 (2022): Journal of Physical Education; e-33512448-2455reponame:Revista da Educação física/UEM (Online)instname:Universidade Estadual de Maringá (UEM)instacron:UEMengporhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/61375/751375154728https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/61375/751375154727Copyright (c) 2022 Machado et alhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMachado, Leandro César Teixeira Medeiros, MateusStival, Marina Moratode Sousa Barbalho, Yuri Gustavode Lima, Filipe Dinatode Lima, Luciano RamosSilva, Alessandro de Oliveirada Silva, Izabel Cristina RodriguesFunghetto, Silvana Schwerz 2023-08-04T19:22:22Zoai:periodicos.uem.br/ojs:article/61375Revistahttps://periodicos.uem.br/ojs/index.php/RevEducFis/PUBhttps://periodicos.uem.br/ojs/index.php/RevEducFis/oai||revdef@uem.br1983-30830103-3948opendoar:2023-08-04T19:22:22Revista da Educação física/UEM (Online) - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
Polimorfismo do gene ACTN3 e os fatores associados ao desempenho funcional de idosas atendidas na atenção primária em saúde
title ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
spellingShingle ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
Machado, Leandro César Teixeira
Functional performance
Genetic variation
Aging
Muscle strengh
Desempenho Funcional
Variação Genética
Envelhecimento
Força muscular
title_short ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
title_full ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
title_fullStr ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
title_full_unstemmed ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
title_sort ACTN 3 gene polymorphism and factors associated with functional performance in elderly women assisted in primary health care
author Machado, Leandro César Teixeira
author_facet Machado, Leandro César Teixeira
Medeiros, Mateus
Stival, Marina Morato
de Sousa Barbalho, Yuri Gustavo
de Lima, Filipe Dinato
de Lima, Luciano Ramos
Silva, Alessandro de Oliveira
da Silva, Izabel Cristina Rodrigues
Funghetto, Silvana Schwerz
author_role author
author2 Medeiros, Mateus
Stival, Marina Morato
de Sousa Barbalho, Yuri Gustavo
de Lima, Filipe Dinato
de Lima, Luciano Ramos
Silva, Alessandro de Oliveira
da Silva, Izabel Cristina Rodrigues
Funghetto, Silvana Schwerz
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Machado, Leandro César Teixeira
Medeiros, Mateus
Stival, Marina Morato
de Sousa Barbalho, Yuri Gustavo
de Lima, Filipe Dinato
de Lima, Luciano Ramos
Silva, Alessandro de Oliveira
da Silva, Izabel Cristina Rodrigues
Funghetto, Silvana Schwerz
dc.subject.por.fl_str_mv Functional performance
Genetic variation
Aging
Muscle strengh
Desempenho Funcional
Variação Genética
Envelhecimento
Força muscular
topic Functional performance
Genetic variation
Aging
Muscle strengh
Desempenho Funcional
Variação Genética
Envelhecimento
Força muscular
description Objective: to analyze the potential influences of the R/X genetic polymorphism of the ACTN3 gene and of anthropometric and metabolic characteristics on the functional performance of elderly women assisted in primary health care. Method: One hundred and forty-one elderly women were evaluated in relation to anthropometric, metabolic, functional, clinical, cognitive and demographic characteristics. The frequencies of alleles and genotypes of the ACTN3 gene polymorphism were determined. Results: 141 elderly women (68.30 ± 6.18 years) were evaluated. There were no significant differences (p > 0.05) between the RR and RX/XX genotypes in the functional performance, anthropometric or metabolic characteristics of the elderly women. The duration of the TUG test showed positive correlations with age, body mass index, waist circumference and fat percentage (s = 0.315; p < 0.001; s = 0.238; p = 0.005; s = 0.174; p = 0.039; s = 0.207; p = 0.014) respectively. Negative correlations were observed between the TUG with absolute (s = - 0.314; p < 0.001) and relative (s = - 0.380; p < 0.001) handgrip strength. Conclusion: In our study, no influences of ACTN3 gene polymorphisms were observed on the functional performance of elderly women, which was influenced by other factors.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-02
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/61375
10.4025/jphyseduc.v33i1.3351
url https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/61375
identifier_str_mv 10.4025/jphyseduc.v33i1.3351
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/61375/751375154728
https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/61375/751375154727
dc.rights.driver.fl_str_mv Copyright (c) 2022 Machado et al
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Machado et al
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil
publisher.none.fl_str_mv Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil
dc.source.none.fl_str_mv Journal of Physical Education; Vol 33 No 1 (2022): Journal of Physical Education; e-3351
Journal of Physical Education; Vol. 33 Núm. 1 (2022): Journal of Physical Education; e-3351
Journal of Physical Education; v. 33 n. 1 (2022): Journal of Physical Education; e-3351
2448-2455
reponame:Revista da Educação física/UEM (Online)
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Revista da Educação física/UEM (Online)
collection Revista da Educação física/UEM (Online)
repository.name.fl_str_mv Revista da Educação física/UEM (Online) - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||revdef@uem.br
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