Morphological study of splenic megakaryocytopoiesis in White New Zealand rabbits in the end of gestation and postnatal period - DOI: 10.4025/actascianimsci.v25i1.2126

• Autor(a) principal: Pacheco, Maria Rita
• Data de Publicação: 2008
• Outros Autores: Nakaghi, Laura Satiko Okada, Artoni, Silvana Martinez Baraldi, Ganeco, Luciana Nakaghi, Carvalho, Alessandra C. Francischini de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Acta Scientiarum. Animal Sciences (Online)
• Texto Completo: https://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/2126
• topic: megacariocitopoiese esplênica; coelhos; 5.04.00.00-2 Zootecnia

Splenic megakaryocytopoiesis was studied in White New Zealand rabbits in the fetal and postnatal phase. The spleen was collected at the 28th fetal day and at 4th, 8th, 12th, 28th, 56th and 84th days after birth. Morphologically, the megakaryocytic cells presented cytoplasm scarce to abundant, lightly basophilc to acidophilic, with large nucleus, reddish and irregular and variable amounts of chromatin loose to dense; the visible number of nucleoli varied depending on the chromatin pattern. It was evidenced megakaryocytopoietic activity and sequence all over the period of the study, by the presence of mature cells, in the 28th day of fetal life and in the 84th day of postnatal, presupposing a subsequent platelets production. It was individualized, sequentially, by megakaryoblast, promegakaryocyte, caryokinetic megakaryocyte, megakaryocite and metamegakaryocyte. We conclude that splenic megakaryocytopoiesis in rabbits produced platelets by presence of stimulator environment of hemocytopoiesis, or more specifically, by inductor microenvironment of megakaryocytopoiesis and thrombocytopoiesis.