MACROSCOPIC AND MICROSCOPIC INJURIES OF PATIENTS AFFECT-ED BY COVID-19

• Autor(a) principal: Evangelista Bezerril, Juliana
• Data de Publicação: 2020
• Outros Autores: Machado, João Paulo, Albino Silva, Samara, Tatiana Granja-Salcedo, Yury
• Tipo de documento: Artigo
• Idioma: eng; spa; por
• Título da fonte: Revista de Ciência Veterinária e Saúde Pública
• Texto Completo: https://periodicos.uem.br/ojs/index.php/RevCiVet/article/view/55500
• topic: necroscopy findings; histopathology; pneumonia

After the first report of an outbreak of acute respiratory syndrome in China in December 2019, a new coronavirus, severe acute respiratory syndrome - coronavirus 2 (SARS-CoV-2) was identified. Despite to the high number of cases and deaths, limited information is available regarding the pathogenesis and injuries caused by the new coronavirus. This study aims to carry out a literature review concerning the macroscopic and microscopic aspects of the disease, since the progression of the disease is closely related to the viral action and the cellular and tissue response in the lesions caused by it. In conclusion COVID-19 is a disease that can affect all types of body tissues. The lesions affect mainly the pulmonary parenchyma and are usually macroscopically observed as consolidation areas, and histologically as plasmacytic lymphoid interstitial pneumonia and with neutrophil infiltration, already observed lesions outside the lung are mainly due to the inflammatory action of lymphocytes and histiocytes, and to the intense production of cytokines with systemic action