Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)

Detalhes bibliográficos
Autor(a) principal: Frollini, Anelena Bueno
Data de Publicação: 2008
Outros Autores: Dias, Rodrigo, Prestes, Jonato, Baganha, Ronaldo Júlio, Cereja, Denise Martins Paneto, Gomes, Leandro Paschoali Rodrigues, Cavaglieri, Cláudia Regina
Tipo de documento: Artigo
Idioma: por
Título da fonte: Journal of Physical Education (Maringá)
Texto Completo: https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/6007
Resumo: Studies demonstrate the existance of de 14 monocarboxylate transporters isoforms (MCTs), proteins of membrane which transport lactate and H+. In contrast, informations concerning the specific function of these several transporters are not specific. On the other hand, others are already well defined. So, the objective of this review was to clarify the effects of exercise on lactate transport and regulation by MCTs. MCT1 and MCT4 are found in muscle, suggesting, thus, distinct functions in the same tissue due to differences of lactate transport and, therefore, may respond differently to modifications in exercise intensities. In addition, its known that endurance training can increase MCT1 muscle content as well as the intense interval training may induce increase in MCT1 and MCT4. These alterations in MCTs contribute to pH control and improve of oxidative capacity.
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spelling Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)EXERCÍCIO FÍSICO E REGULAÇÃO DO LACTATO: PAPEL DOS TRANSPORTADORES DE MONOCARBOXILATO (PROTEÍNAS MCT) - DOI: 10.4025/reveducfis.v19i3.6007Monocarboxylate transportersLactatePerformance.Tranportadores de monocarboxilatosLactatoPerformance4.09.00.00-2 Educação FísicaStudies demonstrate the existance of de 14 monocarboxylate transporters isoforms (MCTs), proteins of membrane which transport lactate and H+. In contrast, informations concerning the specific function of these several transporters are not specific. On the other hand, others are already well defined. So, the objective of this review was to clarify the effects of exercise on lactate transport and regulation by MCTs. MCT1 and MCT4 are found in muscle, suggesting, thus, distinct functions in the same tissue due to differences of lactate transport and, therefore, may respond differently to modifications in exercise intensities. In addition, its known that endurance training can increase MCT1 muscle content as well as the intense interval training may induce increase in MCT1 and MCT4. These alterations in MCTs contribute to pH control and improve of oxidative capacity.Estudos mostram a existência de 14 isoformas de tranportadores de monocarboxilatos (MCTs), proteínas de membana que transportam lactato e H+. Embora muitos desses transportadores ainda não possuam uma função determinada, outros já estão bem descritos. Assim, o objetivo desta revisão foi esclarecer os efeitos do exercício no transporte e regulação do lactato por meio dos MCTs. Os MCT1 e MCT4 são encontrados no músculo, sugerindo, assim, funções distintas no mesmo tecido, devido a diferenças de transporte do lactato, motivo pelo qual podem responder de formas distintas a alterações nas intensidades de exercício. Ademais, é sabido que o treinamento de endurance pode aumentar a concentração de MCT1 muscular, ao passo que o treinamento intervalado intenso pode induzir a aumentos tanto no MCT1 como no MCT4. Tais alterações nos MCTs contribuem para o controle do pH e melhora da capacidade oxidativa.Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil2008-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/6007Journal of Physical Education; Vol 19 No 3 (2008); 453-463Journal of Physical Education; Vol. 19 Núm. 3 (2008); 453-463Journal of Physical Education; v. 19 n. 3 (2008); 453-4632448-2455reponame:Journal of Physical Education (Maringá)instname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/6007/3697Frollini, Anelena BuenoDias, RodrigoPrestes, JonatoBaganha, Ronaldo JúlioCereja, Denise Martins PanetoGomes, Leandro Paschoali RodriguesCavaglieri, Cláudia Reginainfo:eu-repo/semantics/openAccess2023-01-10T15:37:42Zoai:periodicos.uem.br/ojs:article/6007Revistahttp://periodicos.uem.br/ojs/index.php/RevEducFis/indexPUBhttps://old.scielo.br/oai/scielo-oai.php||revdef@uem.br2448-24552448-2455opendoar:2023-01-10T15:37:42Journal of Physical Education (Maringá) - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
EXERCÍCIO FÍSICO E REGULAÇÃO DO LACTATO: PAPEL DOS TRANSPORTADORES DE MONOCARBOXILATO (PROTEÍNAS MCT) - DOI: 10.4025/reveducfis.v19i3.6007
title Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
spellingShingle Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
Frollini, Anelena Bueno
Monocarboxylate transporters
Lactate
Performance.
Tranportadores de monocarboxilatos
Lactato
Performance
4.09.00.00-2 Educação Física
title_short Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
title_full Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
title_fullStr Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
title_full_unstemmed Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
title_sort Physical exercise and regulation of lactate: role of monocarboxylate transports (mct proteins)
author Frollini, Anelena Bueno
author_facet Frollini, Anelena Bueno
Dias, Rodrigo
Prestes, Jonato
Baganha, Ronaldo Júlio
Cereja, Denise Martins Paneto
Gomes, Leandro Paschoali Rodrigues
Cavaglieri, Cláudia Regina
author_role author
author2 Dias, Rodrigo
Prestes, Jonato
Baganha, Ronaldo Júlio
Cereja, Denise Martins Paneto
Gomes, Leandro Paschoali Rodrigues
Cavaglieri, Cláudia Regina
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Frollini, Anelena Bueno
Dias, Rodrigo
Prestes, Jonato
Baganha, Ronaldo Júlio
Cereja, Denise Martins Paneto
Gomes, Leandro Paschoali Rodrigues
Cavaglieri, Cláudia Regina
dc.subject.por.fl_str_mv Monocarboxylate transporters
Lactate
Performance.
Tranportadores de monocarboxilatos
Lactato
Performance
4.09.00.00-2 Educação Física
topic Monocarboxylate transporters
Lactate
Performance.
Tranportadores de monocarboxilatos
Lactato
Performance
4.09.00.00-2 Educação Física
description Studies demonstrate the existance of de 14 monocarboxylate transporters isoforms (MCTs), proteins of membrane which transport lactate and H+. In contrast, informations concerning the specific function of these several transporters are not specific. On the other hand, others are already well defined. So, the objective of this review was to clarify the effects of exercise on lactate transport and regulation by MCTs. MCT1 and MCT4 are found in muscle, suggesting, thus, distinct functions in the same tissue due to differences of lactate transport and, therefore, may respond differently to modifications in exercise intensities. In addition, its known that endurance training can increase MCT1 muscle content as well as the intense interval training may induce increase in MCT1 and MCT4. These alterations in MCTs contribute to pH control and improve of oxidative capacity.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/6007
url https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/6007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/6007/3697
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil
publisher.none.fl_str_mv Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil
dc.source.none.fl_str_mv Journal of Physical Education; Vol 19 No 3 (2008); 453-463
Journal of Physical Education; Vol. 19 Núm. 3 (2008); 453-463
Journal of Physical Education; v. 19 n. 3 (2008); 453-463
2448-2455
reponame:Journal of Physical Education (Maringá)
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Journal of Physical Education (Maringá)
collection Journal of Physical Education (Maringá)
repository.name.fl_str_mv Journal of Physical Education (Maringá) - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||revdef@uem.br
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