Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Journal of Physical Education (Maringá) |
Texto Completo: | https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738 |
Resumo: | Nitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise. |
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Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738Óxido nítrico e exercício: uma revisão - doi: 10.4025/reveducfis.v23i3.11738Nitric oxideExerciseExercisePhysiologyHealth.Óxido nítricoExercício.ExercícioSaúdeFisiologiaNitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise.O óxido nítrico (NO) é um potente vasodilatador com papel importante no controle do tônus vascular. Estudos têm demonstrado a função do NO na preservação da capacidade funcional do endotélio, prevenindo aterosclerose, lesão vascular, hipertensão, entre outras. Por outro lado, fatores genotípicos e/ou fenotípicos podem diminuir sua biodisponibilidade, resultando em disfunção endotelial grave, aumentando a resistência vascular periférica. Recentes estudos têm demonstrado que o exercício aumenta a biodisponibilidade do NO de forma aguda e crônica. Porém a produção do conhecimento relacionado ao NO mediado pelo exercício ainda apresenta lacunas. Neste sentido, o objetivo desta revisão é tentar elucidar os mecanismos celulares envolvidos na síntese e regulação do NO, e demonstrar o avanço do conhecimento cientifico relacionado à biodisponibilidade de NO mediado pelo exercício. Para tanto, esta revisão foram utilizados livros e periódicos das bases de dados PubMed, HIGWIRE, SciELO e LILACS utilizando as palavras chaves “nitric oxide” e “exercise” para a busca de publicações. As principais considerações do estudo foram que o exercício físico pode aumentar a biodisponibilidade de NO de forma aguda, e as adaptações crônicas do exercício em relação aos parâmetros cardiovasculares são dependentes do aumento da biodisponibilidade de NO induzida pelo exercício.Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil2012-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionReview of literatureRevisão de literaturaapplication/pdfhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738Journal of Physical Education; Vol 23 No 3 (2012); 469-481Journal of Physical Education; Vol. 23 Núm. 3 (2012); 469-481Journal of Physical Education; v. 23 n. 3 (2012); 469-4812448-2455reponame:Journal of Physical Education (Maringá)instname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738/10467Souza Junior, Tácito PessoaAsano, Ricardo YukioPrestes, JonatoSales, Marcelo MagalhãesCoelho, João MaurícioSimões, Herbert Gustavoinfo:eu-repo/semantics/openAccess2023-01-10T15:38:06Zoai:periodicos.uem.br/ojs:article/11738Revistahttp://periodicos.uem.br/ojs/index.php/RevEducFis/indexPUBhttps://old.scielo.br/oai/scielo-oai.php||revdef@uem.br2448-24552448-2455opendoar:2023-01-10T15:38:06Journal of Physical Education (Maringá) - Universidade Estadual de Maringá (UEM)false |
dc.title.none.fl_str_mv |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 Óxido nítrico e exercício: uma revisão - doi: 10.4025/reveducfis.v23i3.11738 |
title |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 |
spellingShingle |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 Souza Junior, Tácito Pessoa Nitric oxide Exercise Exercise Physiology Health. Óxido nítrico Exercício. Exercício Saúde Fisiologia |
title_short |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 |
title_full |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 |
title_fullStr |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 |
title_full_unstemmed |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 |
title_sort |
Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738 |
author |
Souza Junior, Tácito Pessoa |
author_facet |
Souza Junior, Tácito Pessoa Asano, Ricardo Yukio Prestes, Jonato Sales, Marcelo Magalhães Coelho, João Maurício Simões, Herbert Gustavo |
author_role |
author |
author2 |
Asano, Ricardo Yukio Prestes, Jonato Sales, Marcelo Magalhães Coelho, João Maurício Simões, Herbert Gustavo |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Souza Junior, Tácito Pessoa Asano, Ricardo Yukio Prestes, Jonato Sales, Marcelo Magalhães Coelho, João Maurício Simões, Herbert Gustavo |
dc.subject.por.fl_str_mv |
Nitric oxide Exercise Exercise Physiology Health. Óxido nítrico Exercício. Exercício Saúde Fisiologia |
topic |
Nitric oxide Exercise Exercise Physiology Health. Óxido nítrico Exercício. Exercício Saúde Fisiologia |
description |
Nitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-09-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Review of literature Revisão de literatura |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738 |
url |
https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738/10467 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil |
publisher.none.fl_str_mv |
Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil |
dc.source.none.fl_str_mv |
Journal of Physical Education; Vol 23 No 3 (2012); 469-481 Journal of Physical Education; Vol. 23 Núm. 3 (2012); 469-481 Journal of Physical Education; v. 23 n. 3 (2012); 469-481 2448-2455 reponame:Journal of Physical Education (Maringá) instname:Universidade Estadual de Maringá (UEM) instacron:UEM |
instname_str |
Universidade Estadual de Maringá (UEM) |
instacron_str |
UEM |
institution |
UEM |
reponame_str |
Journal of Physical Education (Maringá) |
collection |
Journal of Physical Education (Maringá) |
repository.name.fl_str_mv |
Journal of Physical Education (Maringá) - Universidade Estadual de Maringá (UEM) |
repository.mail.fl_str_mv |
||revdef@uem.br |
_version_ |
1754732543333105664 |