Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738

Detalhes bibliográficos
Autor(a) principal: Souza Junior, Tácito Pessoa
Data de Publicação: 2012
Outros Autores: Asano, Ricardo Yukio, Prestes, Jonato, Sales, Marcelo Magalhães, Coelho, João Maurício, Simões, Herbert Gustavo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Journal of Physical Education (Maringá)
Texto Completo: https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738
Resumo: Nitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise.
id UEM-9_84ce60b5209ba737fa07a673efc58038
oai_identifier_str oai:periodicos.uem.br/ojs:article/11738
network_acronym_str UEM-9
network_name_str Journal of Physical Education (Maringá)
repository_id_str
spelling Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738Óxido nítrico e exercício: uma revisão - doi: 10.4025/reveducfis.v23i3.11738Nitric oxideExerciseExercisePhysiologyHealth.Óxido nítricoExercício.ExercícioSaúdeFisiologiaNitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise.O óxido nítrico (NO) é um potente vasodilatador com papel importante no controle do tônus vascular. Estudos têm demonstrado a função do NO na preservação da capacidade funcional do endotélio, prevenindo aterosclerose, lesão vascular, hipertensão, entre outras. Por outro lado, fatores genotípicos e/ou fenotípicos podem diminuir sua biodisponibilidade, resultando em disfunção endotelial grave, aumentando a resistência vascular periférica. Recentes estudos têm demonstrado que o exercício aumenta a biodisponibilidade do NO de forma aguda e crônica. Porém a produção do conhecimento relacionado ao NO mediado pelo exercício ainda apresenta lacunas. Neste sentido, o objetivo desta revisão é tentar elucidar os mecanismos celulares envolvidos na síntese e regulação do NO, e demonstrar o avanço do conhecimento cientifico relacionado à biodisponibilidade de NO mediado pelo exercício. Para tanto, esta revisão foram utilizados livros e periódicos das bases de dados PubMed, HIGWIRE, SciELO e LILACS utilizando as palavras chaves “nitric oxide” e “exercise” para a busca de publicações. As principais considerações do estudo foram que o exercício físico pode aumentar a biodisponibilidade de NO de forma aguda, e as adaptações crônicas do exercício em relação aos parâmetros  cardiovasculares são dependentes do aumento da biodisponibilidade de NO induzida pelo exercício.Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil2012-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionReview of literatureRevisão de literaturaapplication/pdfhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738Journal of Physical Education; Vol 23 No 3 (2012); 469-481Journal of Physical Education; Vol. 23 Núm. 3 (2012); 469-481Journal of Physical Education; v. 23 n. 3 (2012); 469-4812448-2455reponame:Journal of Physical Education (Maringá)instname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttps://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738/10467Souza Junior, Tácito PessoaAsano, Ricardo YukioPrestes, JonatoSales, Marcelo MagalhãesCoelho, João MaurícioSimões, Herbert Gustavoinfo:eu-repo/semantics/openAccess2023-01-10T15:38:06Zoai:periodicos.uem.br/ojs:article/11738Revistahttp://periodicos.uem.br/ojs/index.php/RevEducFis/indexPUBhttps://old.scielo.br/oai/scielo-oai.php||revdef@uem.br2448-24552448-2455opendoar:2023-01-10T15:38:06Journal of Physical Education (Maringá) - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
Óxido nítrico e exercício: uma revisão - doi: 10.4025/reveducfis.v23i3.11738
title Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
spellingShingle Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
Souza Junior, Tácito Pessoa
Nitric oxide
Exercise
Exercise
Physiology
Health.
Óxido nítrico
Exercício.
Exercício
Saúde
Fisiologia
title_short Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
title_full Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
title_fullStr Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
title_full_unstemmed Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
title_sort Nitric oxide and exercise: a review - doi: 10.4025/reveducfis.v23i3.11738
author Souza Junior, Tácito Pessoa
author_facet Souza Junior, Tácito Pessoa
Asano, Ricardo Yukio
Prestes, Jonato
Sales, Marcelo Magalhães
Coelho, João Maurício
Simões, Herbert Gustavo
author_role author
author2 Asano, Ricardo Yukio
Prestes, Jonato
Sales, Marcelo Magalhães
Coelho, João Maurício
Simões, Herbert Gustavo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Souza Junior, Tácito Pessoa
Asano, Ricardo Yukio
Prestes, Jonato
Sales, Marcelo Magalhães
Coelho, João Maurício
Simões, Herbert Gustavo
dc.subject.por.fl_str_mv Nitric oxide
Exercise
Exercise
Physiology
Health.
Óxido nítrico
Exercício.
Exercício
Saúde
Fisiologia
topic Nitric oxide
Exercise
Exercise
Physiology
Health.
Óxido nítrico
Exercício.
Exercício
Saúde
Fisiologia
description Nitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise.
publishDate 2012
dc.date.none.fl_str_mv 2012-09-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Review of literature
Revisão de literatura
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738
url https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738/10467
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil
publisher.none.fl_str_mv Department of Physical Education - State University of Maringá (UEM), Maringá-PR, Brazil
dc.source.none.fl_str_mv Journal of Physical Education; Vol 23 No 3 (2012); 469-481
Journal of Physical Education; Vol. 23 Núm. 3 (2012); 469-481
Journal of Physical Education; v. 23 n. 3 (2012); 469-481
2448-2455
reponame:Journal of Physical Education (Maringá)
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Journal of Physical Education (Maringá)
collection Journal of Physical Education (Maringá)
repository.name.fl_str_mv Journal of Physical Education (Maringá) - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||revdef@uem.br
_version_ 1754732543333105664