The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) |
Texto Completo: | https://revista.uepb.edu.br/PBOCI/article/view/972 |
Resumo: | Objective: To describe and evaluate the xylitol products’ applicability and its effects in the health area worldwide utilizing a bibliometric analysis from randomized controlled trials (RCT) with humans. Material and Methods: Electronic searches were carried out in Medline/PubMed, Scopus, Cochrane Library, Web of Science, and VHL databases. The main data extracted were: year, area of applicability, type of treatment, country, journal, xylitol posology and concentration, presentation form, outcomes, and effects. Results: From 1476 studies, 257 were included. These studies were published between 1973-2021. The majority was carried out in dentistry (73.9%) and under preventive treatment (67.4%). These studies were developed in the USA (15.4%) and published in Caries Research (6.6%). The posology and concentration ranged between 0.004-67 g/day and 0.002-100%, respectively. The xylitol is usually used in the chewing gum form (44.0%), and for antimicrobial activity evaluation (38.5%). A positive effect was observed in 204 studies (79.3%) and was associated with xylitol concentration ≥ 15% (p=0.007). Side effects were reported in 8.2% and were associated with posology ≥ 5 g/day (p=0.03). Conclusion: Most studies with xylitol were conducted to prevent diseases in the dentistry field. The chewing gum form and antimicrobial activity evaluation were more frequent. Most xylitol products have a positive effect, and few studies report side effects. |
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The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled TrialsXylitolTherapeuticsRandomized Controlled Trials as TopicBibliometricsObjective: To describe and evaluate the xylitol products’ applicability and its effects in the health area worldwide utilizing a bibliometric analysis from randomized controlled trials (RCT) with humans. Material and Methods: Electronic searches were carried out in Medline/PubMed, Scopus, Cochrane Library, Web of Science, and VHL databases. The main data extracted were: year, area of applicability, type of treatment, country, journal, xylitol posology and concentration, presentation form, outcomes, and effects. Results: From 1476 studies, 257 were included. These studies were published between 1973-2021. The majority was carried out in dentistry (73.9%) and under preventive treatment (67.4%). These studies were developed in the USA (15.4%) and published in Caries Research (6.6%). The posology and concentration ranged between 0.004-67 g/day and 0.002-100%, respectively. The xylitol is usually used in the chewing gum form (44.0%), and for antimicrobial activity evaluation (38.5%). A positive effect was observed in 204 studies (79.3%) and was associated with xylitol concentration ≥ 15% (p=0.007). Side effects were reported in 8.2% and were associated with posology ≥ 5 g/day (p=0.03). Conclusion: Most studies with xylitol were conducted to prevent diseases in the dentistry field. The chewing gum form and antimicrobial activity evaluation were more frequent. Most xylitol products have a positive effect, and few studies report side effects.EDUEPB - EDITORA DA UNIVERSIDADE ESTADUAL DA PARAÍBA2022-02-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revista.uepb.edu.br/PBOCI/article/view/972Pesquisa Brasileira em Odontopediatria e Clínica Integrada; Vol. 22 (2022); e210046Pesquisa Brasileira em Odontopediatria e Clínica Integrada; v. 22 (2022); e2100461983-46321519-0501reponame:Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online)instname:Universidade Estadual da Paraíba (UEPB)instacron:UEPBenghttps://revista.uepb.edu.br/PBOCI/article/view/972/640Copyright (c) 2022 Pesquisa Brasileira em Odontopediatria e Clínica Integradahttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessMartins, Mariana Leonel Leite, Karla Lorene de França Magno, Marcela Baraúna Masterson, Daniele Vicente-Gomila, José Miguel Cavalcanti, Yuri Wanderley Maia, Lucianne Cople Fonseca-Gonçalves, Andréa 2022-07-13T17:49:12Zoai:ojs.pkp.sfu.ca:article/972Revistahttps://revista.uepb.edu.br/PBOCI/PUBhttps://revista.uepb.edu.br/PBOCI/oaipboci.editoria@gmail.com || alessandrouepb@gmail.com1983-46321519-0501opendoar:2022-07-13T17:49:12Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) - Universidade Estadual da Paraíba (UEPB)false |
dc.title.none.fl_str_mv |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
title |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
spellingShingle |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials Martins, Mariana Leonel Xylitol Therapeutics Randomized Controlled Trials as Topic Bibliometrics |
title_short |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
title_full |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
title_fullStr |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
title_full_unstemmed |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
title_sort |
The Xylitol Applicability and its Effects in Health Area Worldwide: A Bibliometric Analysis Based on Randomized Controlled Trials |
author |
Martins, Mariana Leonel |
author_facet |
Martins, Mariana Leonel Leite, Karla Lorene de França Magno, Marcela Baraúna Masterson, Daniele Vicente-Gomila, José Miguel Cavalcanti, Yuri Wanderley Maia, Lucianne Cople Fonseca-Gonçalves, Andréa |
author_role |
author |
author2 |
Leite, Karla Lorene de França Magno, Marcela Baraúna Masterson, Daniele Vicente-Gomila, José Miguel Cavalcanti, Yuri Wanderley Maia, Lucianne Cople Fonseca-Gonçalves, Andréa |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Martins, Mariana Leonel Leite, Karla Lorene de França Magno, Marcela Baraúna Masterson, Daniele Vicente-Gomila, José Miguel Cavalcanti, Yuri Wanderley Maia, Lucianne Cople Fonseca-Gonçalves, Andréa |
dc.subject.por.fl_str_mv |
Xylitol Therapeutics Randomized Controlled Trials as Topic Bibliometrics |
topic |
Xylitol Therapeutics Randomized Controlled Trials as Topic Bibliometrics |
description |
Objective: To describe and evaluate the xylitol products’ applicability and its effects in the health area worldwide utilizing a bibliometric analysis from randomized controlled trials (RCT) with humans. Material and Methods: Electronic searches were carried out in Medline/PubMed, Scopus, Cochrane Library, Web of Science, and VHL databases. The main data extracted were: year, area of applicability, type of treatment, country, journal, xylitol posology and concentration, presentation form, outcomes, and effects. Results: From 1476 studies, 257 were included. These studies were published between 1973-2021. The majority was carried out in dentistry (73.9%) and under preventive treatment (67.4%). These studies were developed in the USA (15.4%) and published in Caries Research (6.6%). The posology and concentration ranged between 0.004-67 g/day and 0.002-100%, respectively. The xylitol is usually used in the chewing gum form (44.0%), and for antimicrobial activity evaluation (38.5%). A positive effect was observed in 204 studies (79.3%) and was associated with xylitol concentration ≥ 15% (p=0.007). Side effects were reported in 8.2% and were associated with posology ≥ 5 g/day (p=0.03). Conclusion: Most studies with xylitol were conducted to prevent diseases in the dentistry field. The chewing gum form and antimicrobial activity evaluation were more frequent. Most xylitol products have a positive effect, and few studies report side effects. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-02-02 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revista.uepb.edu.br/PBOCI/article/view/972 |
url |
https://revista.uepb.edu.br/PBOCI/article/view/972 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revista.uepb.edu.br/PBOCI/article/view/972/640 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Pesquisa Brasileira em Odontopediatria e Clínica Integrada https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Pesquisa Brasileira em Odontopediatria e Clínica Integrada https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
EDUEPB - EDITORA DA UNIVERSIDADE ESTADUAL DA PARAÍBA |
publisher.none.fl_str_mv |
EDUEPB - EDITORA DA UNIVERSIDADE ESTADUAL DA PARAÍBA |
dc.source.none.fl_str_mv |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada; Vol. 22 (2022); e210046 Pesquisa Brasileira em Odontopediatria e Clínica Integrada; v. 22 (2022); e210046 1983-4632 1519-0501 reponame:Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) instname:Universidade Estadual da Paraíba (UEPB) instacron:UEPB |
instname_str |
Universidade Estadual da Paraíba (UEPB) |
instacron_str |
UEPB |
institution |
UEPB |
reponame_str |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) |
collection |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) |
repository.name.fl_str_mv |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) - Universidade Estadual da Paraíba (UEPB) |
repository.mail.fl_str_mv |
pboci.editoria@gmail.com || alessandrouepb@gmail.com |
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1803387862916268032 |