Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) |
Texto Completo: | https://revista.uepb.edu.br/PBOCI/article/view/1122 |
Resumo: | Objective: To perform an in vitro analysis of antibacterial and antifungal potential of an alcoholic extract from the leaves of Guapira Graciliflora Mart. against oral microorganisms and determine its chemical composition. Material and Methods: A hydroalcoholic extract of the leaves form G. graciliflora was obtained through maceration, vacuum concentration and freeze-drying. Antibacterial and antifungal activities were evaluated against Streptococcus mutans, Streptococcus salivarius, Streptococcus oralis, Streptococcus parasanguinis, Streptococcus mitis and strains of Candida albicans using broth microdilution method. Phytochemical analysis determined the total phenolic compounds, protein concentration and total of sugars present in the extract. Results: G. Graciliflora demonstrated antifungal activity against the LM 11 and LM 410 clinical isolates of C. albicans (MIC 0.5 mg/mL and 2 mg/mL, respectively). The other microorganisms tested were resistant to the extract. The phytochemical analysis revealed 3% proteins, 13% total sugars and 17% phenolic compounds. Conclusion: G. Graciliflora has antifungal activity against clinical strains of C. albicans and exhibits proteins, sugars and phenolic compounds in its chemical composition. |
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Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental InterestPlants, MedicinalPlant ExtractsPhytotherapyAnti-Infective AgentsObjective: To perform an in vitro analysis of antibacterial and antifungal potential of an alcoholic extract from the leaves of Guapira Graciliflora Mart. against oral microorganisms and determine its chemical composition. Material and Methods: A hydroalcoholic extract of the leaves form G. graciliflora was obtained through maceration, vacuum concentration and freeze-drying. Antibacterial and antifungal activities were evaluated against Streptococcus mutans, Streptococcus salivarius, Streptococcus oralis, Streptococcus parasanguinis, Streptococcus mitis and strains of Candida albicans using broth microdilution method. Phytochemical analysis determined the total phenolic compounds, protein concentration and total of sugars present in the extract. Results: G. Graciliflora demonstrated antifungal activity against the LM 11 and LM 410 clinical isolates of C. albicans (MIC 0.5 mg/mL and 2 mg/mL, respectively). The other microorganisms tested were resistant to the extract. The phytochemical analysis revealed 3% proteins, 13% total sugars and 17% phenolic compounds. Conclusion: G. Graciliflora has antifungal activity against clinical strains of C. albicans and exhibits proteins, sugars and phenolic compounds in its chemical composition.EDUEPB - EDITORA DA UNIVERSIDADE ESTADUAL DA PARAÍBA2022-03-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revista.uepb.edu.br/PBOCI/article/view/1122Pesquisa Brasileira em Odontopediatria e Clínica Integrada; Vol. 20 (2020); e5165Pesquisa Brasileira em Odontopediatria e Clínica Integrada; v. 20 (2020); e51651983-46321519-0501reponame:Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online)instname:Universidade Estadual da Paraíba (UEPB)instacron:UEPBenghttps://revista.uepb.edu.br/PBOCI/article/view/1122/838Copyright (c) 2020 Pesquisa Brasileira em Odontopediatria e Clínica Integradahttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessde Araújo, Thiara Karine Costa, Edja Maria Melo de Brito Maia, Carolina Medeiros de Almeida Alves, Pollianna Muniz Nonaka, Cassiano Francisco Weege Silva, Priscilla Guimarães Lima, Rennaly de Freitas Godoy, Gustavo Pina 2022-03-19T19:32:24Zoai:ojs.pkp.sfu.ca:article/1122Revistahttps://revista.uepb.edu.br/PBOCI/PUBhttps://revista.uepb.edu.br/PBOCI/oaipboci.editoria@gmail.com || alessandrouepb@gmail.com1983-46321519-0501opendoar:2022-03-19T19:32:24Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) - Universidade Estadual da Paraíba (UEPB)false |
dc.title.none.fl_str_mv |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest |
title |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest |
spellingShingle |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest de Araújo, Thiara Karine Plants, Medicinal Plant Extracts Phytotherapy Anti-Infective Agents |
title_short |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest |
title_full |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest |
title_fullStr |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest |
title_full_unstemmed |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest |
title_sort |
Chemical Composition, Antibacterial and Antifungal Potential of an Extract From the Leaves of Guapira Graciliflora Mart. Against Oral Microorganisms of Dental Interest |
author |
de Araújo, Thiara Karine |
author_facet |
de Araújo, Thiara Karine Costa, Edja Maria Melo de Brito Maia, Carolina Medeiros de Almeida Alves, Pollianna Muniz Nonaka, Cassiano Francisco Weege Silva, Priscilla Guimarães Lima, Rennaly de Freitas Godoy, Gustavo Pina |
author_role |
author |
author2 |
Costa, Edja Maria Melo de Brito Maia, Carolina Medeiros de Almeida Alves, Pollianna Muniz Nonaka, Cassiano Francisco Weege Silva, Priscilla Guimarães Lima, Rennaly de Freitas Godoy, Gustavo Pina |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
de Araújo, Thiara Karine Costa, Edja Maria Melo de Brito Maia, Carolina Medeiros de Almeida Alves, Pollianna Muniz Nonaka, Cassiano Francisco Weege Silva, Priscilla Guimarães Lima, Rennaly de Freitas Godoy, Gustavo Pina |
dc.subject.por.fl_str_mv |
Plants, Medicinal Plant Extracts Phytotherapy Anti-Infective Agents |
topic |
Plants, Medicinal Plant Extracts Phytotherapy Anti-Infective Agents |
description |
Objective: To perform an in vitro analysis of antibacterial and antifungal potential of an alcoholic extract from the leaves of Guapira Graciliflora Mart. against oral microorganisms and determine its chemical composition. Material and Methods: A hydroalcoholic extract of the leaves form G. graciliflora was obtained through maceration, vacuum concentration and freeze-drying. Antibacterial and antifungal activities were evaluated against Streptococcus mutans, Streptococcus salivarius, Streptococcus oralis, Streptococcus parasanguinis, Streptococcus mitis and strains of Candida albicans using broth microdilution method. Phytochemical analysis determined the total phenolic compounds, protein concentration and total of sugars present in the extract. Results: G. Graciliflora demonstrated antifungal activity against the LM 11 and LM 410 clinical isolates of C. albicans (MIC 0.5 mg/mL and 2 mg/mL, respectively). The other microorganisms tested were resistant to the extract. The phytochemical analysis revealed 3% proteins, 13% total sugars and 17% phenolic compounds. Conclusion: G. Graciliflora has antifungal activity against clinical strains of C. albicans and exhibits proteins, sugars and phenolic compounds in its chemical composition. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revista.uepb.edu.br/PBOCI/article/view/1122 |
url |
https://revista.uepb.edu.br/PBOCI/article/view/1122 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revista.uepb.edu.br/PBOCI/article/view/1122/838 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Pesquisa Brasileira em Odontopediatria e Clínica Integrada https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Pesquisa Brasileira em Odontopediatria e Clínica Integrada https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
EDUEPB - EDITORA DA UNIVERSIDADE ESTADUAL DA PARAÍBA |
publisher.none.fl_str_mv |
EDUEPB - EDITORA DA UNIVERSIDADE ESTADUAL DA PARAÍBA |
dc.source.none.fl_str_mv |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada; Vol. 20 (2020); e5165 Pesquisa Brasileira em Odontopediatria e Clínica Integrada; v. 20 (2020); e5165 1983-4632 1519-0501 reponame:Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) instname:Universidade Estadual da Paraíba (UEPB) instacron:UEPB |
instname_str |
Universidade Estadual da Paraíba (UEPB) |
instacron_str |
UEPB |
institution |
UEPB |
reponame_str |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) |
collection |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) |
repository.name.fl_str_mv |
Pesquisa Brasileira em Odontopediatria e Clínica Integrada (Online) - Universidade Estadual da Paraíba (UEPB) |
repository.mail.fl_str_mv |
pboci.editoria@gmail.com || alessandrouepb@gmail.com |
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1803387863410147328 |